November 2009
Critical role of s465 in protein kinase C-increased rat glutamate transporter type 3 activity.
Baik HJ, Huang Y, Washington JM, Zuo Z.
Int J Neurosci 2009. [Abstract] [Full Text] [PDF]
Transcription factor REST negatively influences the protein kinase C-dependent up-regulation of human mu-opioid receptor gene transcription.
Bedini A, Baiula M, Carbonari G, Spampinato S.
Neurochem Int 2009. [Full Text] [PDF]
Synaptic activity-related classical protein kinase C isoform localization in the adult rat neuromuscular synapse.
Besalduch N, Tomas M, Santafe MM, Garcia N, Tomas J, Lanuza MA.
J Comp Neurol 2009. [Abstract] [Full Text] [PDF]
Protein kinases A and C and phosphatidylinositol 3 kinase regulate glycogen synthase kinase-3A serine 21 phosphorylation in boar spermatozoa.
Bragado MJ, Aparicio IM, Gil MC, Garcia-Marin LJ.
J Cell Biochem 2009. [Abstract] [Full Text] [PDF]
Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCvarepsilon) knockout mice.
Budas GR, Disatnik MH, Chen CH, Mochly-Rosen D.
J Mol Cell Cardiol 2009. [Full Text] [PDF]
Protein kinase C - A family of protein kinases, allosteric effectors or both?
Cameron AJ, Parker PJ.
Adv Enzyme Regul 2009. [Full Text] [PDF]
Conventional protein kinase C plays a critical role in negative regulation of CD98-induced homotypic aggregation.
Cho JY, Katz DR, Skubitz KM, Chain BM.
Tissue Antigens 2009. [Abstract] [Full Text] [PDF]
Protein kinase C as a peripheral biomarker for Alzheimer's disease.
de Barry J, Liegeois CM, Janoshazi A.
Exp Gerontol 2009. [Full Text] [PDF]
The neuropathy-protective agent acetyl-l-carnitine activates protein kinase C-
gamma and MAPKs in a rat model of neuropathic pain.
Di Cesare Mannelli L, Ghelardini C, Toscano A, Pacini A, Bartolini A.
Neuroscience 2009. [Full Text] [PDF]
A role for the phosphatidylinositol 3-kinase--protein kinase C zeta--Sp1
pathway in the 1,25-dihydroxyvitamin D3 induction of the 25-hydroxyvitaminD3 24-hydroxylase gene in human kidney cells.
Dwivedi PP, Gao XH, Tan JC, Evdokiou A, Ferrante A, Morris HA, et al.
Cell Signal 2009. [Full Text] [PDF]
Upregulation of Cytoplasmic Gelsolin, an Amyloid-beta-Binding Protein, Under
Oxidative Stress Conditions: Involvement of Protein Kinase C.
Ji L, Chauhan A, Chauhan V.
J Alzheimers Dis 2009. [Abstract]
Protein Kinase C-alpha Activation Induces NF-kappaB-Dependent VCAM-1
Expression in Cultured Human Umbilical Vein Endothelial Cells Treated with
Sera from Preeclamptic Patients.
Jiang R, Teng Y, Huang Y, Gu J, Li M.
Gynecol Obstet Invest 2009. [Abstract]
High molecular weight FGF-2 promotes postconditioning-like cardioprotection
linked to activation of the protein kinase C isoforms Akt and p70 S6 kinase.
Jiang ZS, Wen GB, Tang ZH, Srisakuldee W, Fandrich RR, Kardami E.
Can J Physiol Pharmacol 2009. [PDF]
Mutation of the hydrophobic motif in a phosphorylation-deficient mutant
renders protein kinase C delta more apoptotically active.
Karmacharya MB, Jang JI, Lee YJ, Lee YS, Soh JW.
Arch Biochem Biophys 2009. [Full Text] [PDF]
Effects of protein kinase Cdelta and phospholipase C-gamma1 on monocyte
chemoattractant protein-1 expression in taxol-induced breast cancer cell death.
Kim YS, An HT, Kim J, Ko J.
Int J Mol Med 2009. [Abstract]
Shear stress stimulates nitric oxide signaling in pulmonary arterial endothelial
cells via a reduction in catalase activity: role of protein kinase C delta.
Kumar S, Sud N, Fonseca FV, Hou Y, Black SM.
Am J Physiol Lung Cell Mol Physiol 2009. [Abstract]
p34SEI-1 inhibits doxorubicin-induced senescence through a pathway
mediated by protein kinase C-delta and c-Jun-NH2-kinase 1 activation in
human breast cancer MCF7 cells.
Lee SL, Hong SW, Shin JS, Kim JS, Ko SG, Hong NJ, et al.
Mol Cancer Res 2009. [Abstract]
The role of protein kinase C in the synergistic interaction of safingol and
irinotecan in colon cancer cells.
Ling LU, Lin H, Tan KB, Chiu GN.
Int J Oncol 2009. [Abstract]
c-Jun regulates phosphoinositide-dependent kinase 1 transcription:
implication for Akt and protein kinase C activities and melanoma
tumorigenesis.
Lopez-Bergami P, Kim H, Dewing A, Goydos J, Aaronson S, Ronai Z.
J Biol Chem 2009. [Abstract]
Serine 649 phosphorylation within the protein kinase C-regulated domain
down-regulates CARMA1 activity in lymphocytes.
Moreno-Garcia ME, Sommer K, Haftmann C, Sontheimer C, Andrews SF, Rawlings DJ.
J Immunol 2009. [Abstract] [Full Text] [PDF]
Protein Kinase C: Poised to Signal.
Alexandra Newton
Am J Physiol Endocrinol Metab. published 24 November 2009, 10.1152/ajpendo.00477.2009 [Abstract] [PDF]
Oxidative stress in MCF-7 cells is involved in the effects of retinoic acid-induced activation of protein kinase C-delta on insulin-like growth factor-I
secretion and synthesis.
Oh YI, Kim JH, Kang CW.
Growth Horm IGF Res 2009. [Full Text] [PDF]
Protein kinase C activators as synaptogenic and memory therapeutics.
Sun MK, Alkon DL.
Arch Pharm (Weinheim) 2009. [Abstract] [PDF]
Protein kinase C is inhibited by bisphosphonates in prostate cancer PC-3 cells.
Tatsuda Y, Iguchi K, Usui S, Suzui M, Hirano K.
Eur J Pharmacol 2009. [Full Text] [PDF]
Enzastaurin (LY317615), a Protein Kinase C Beta Selective Inhibitor, Enhances
Antiangiogenic Effect of Radiation.
Willey CD, Xiao D, Tu T, Woon Kim K, Moretti L, Niermann KJ, et al. Int J Radiat
Oncol Biol Phys 2009. [Full Text] [PDF]
Rac/ROS-related protein kinase C and phosphatidylinositol-3-kinase signaling
are involved in a negative regulating cascade in B cell activation by antibody-mediated cross-linking of MHC class II molecules.
Yang HY, Kim J, Lee KY, Jang YS.
Mol Immunol 2009. [Full Text] [PDF]
Synergistic Anti-Fibrotic Efficacy of Statin and Protein Kinase C Inhibitor in
Hepatic Fibrosis.
Yang JI, Yoon JH, Bang YJ, Lee SH, Lee SM, Byun HJ, et al.
Am J Physiol Gastrointest Liver Physiol 2009. [Abstract]
Adenosine A(1) receptors selectively target protein kinase C isoforms to the
caveolin-rich plasma membrane in cardiac myocytes.
Yang Z, Sun W, Hu K.
Biochim Biophys Acta 2009. [Full Text] [PDF]
Claudin-1 acts through c-Abl-protein kinase Cdelta (PKCdelta) signaling and
has a causal role in the acquisition of invasive capacity in human liver cells.
Yoon CH, Kim MJ, Park MJ, Park IC, Hwang SG, An S, et al.
J Biol Chem 2009. [Abstract]
The IGF-I Receptor Can Alter the Matrix Metalloproteinase Repertoire of Tumor Cells through Transcriptional Regulation of PKC-{alpha}
Shun Li, Donglei Zhang, Long Yang, Julia V. Burnier, Ni Wang, Rongtuan Lin, Eunice R. Lee, Robert I. Glazer, and Pnina Brodt
Mol. Endocrinol. 2009; 23:2013-2025. [Abstract] [Full Text] [PDF]
Maturation and the role of PKC-mediated contractility in ovine cerebral arteries
Ravi Goyal, Ashwani Mittal, Nina Chu, Lijun Shi, Lubo Zhang, and Lawrence D. Longo
Am J Physiol Heart Circ Physiol. 2009; 297:H2242-H2252. [Abstract] [Full Text] [PDF]
Caspase-mediated protein kinase C{delta}- cleavage is necessary for apoptosis of vascular smooth muscle cells
Kaori Kato, Dai Yamanouchi, Karla Esbona, Kentaro Kamiya, Fan Zhang, K. Craig Kent, and Bo Liu
Am J Physiol Heart Circ Physiol. 2009; 297:H2253-H2261. [Abstract] [Full Text] [PDF]
Atypical Protein Kinase C Activity in the Hypothalamus Is Required for Lipopolysaccharide-Mediated Sickness Responses
Joshua P. Thaler, Sun Ju Choi, Mini P. Sajan, Kayoko Ogimoto, Hong T. Nguyen, Miles Matsen, Stephen C. Benoit, Brent E. Wisse, Robert V. Farese, and Michael W. Schwartz
Endocrinology. 2009; 150:5362-5372. [Abstract] [Full Text] [PDF]
Androgens Induce Dopaminergic Neurotoxicity via Caspase-3-Dependent Activation of Protein Kinase C{delta}
Rebecca L. Cunningham, Andrea Giuffrida, and James L. Roberts
Endocrinology. 2009; 150:5539-5548. [Abstract] [Full Text] [PDF]
Protein Kinase C{delta} Supports Survival of MDA-MB-231 Breast Cancer Cells by Suppressing the ERK1/2 Pathway
Gry Kalstad Lønne, Katarzyna Chmielarska Masoumi, Johan Lennartsson, and Christer Larsson
J. Biol. Chem. 2009; 284:33456-33465. [Abstract] [Full Text] [PDF]