August 2009Inhibition of protein kinase C is not sufficient to prevent or reverse effects of VEGF165 on claudin-1 and permeability in microvascular retinal endothelial cells.
Deissler HL, Deissler H, Lang GE.
Invest Ophthalmol Vis Sci,2009. [Abstract] [Full Text] [PDF]

Excitatory roles of protein kinase C in striatal cholinergic interneurons.
Deng P, Pang ZP, Lei Z, Xu ZC.
J Neurophysiol 2009. [Abstract]

Losartan metabolite EXP3179 blocks NADPH oxidase-mediated superoxide production by inhibiting protein kinase C: potential clinical implications in hypertension.
Fortuno A, Bidegain J, Robador PA, Hermida J, Lopez-Sagaseta J, Beloqui O, et al.
Hypertension 2009. [Abstract] [Full Text] [PDF]

Activation of ERK1/2 by protein kinase C-alpha in response to hydrogen peroxide-induced cell death in human gingival fibroblasts.
Gutierrez-Venegas G, Arreguin-Cano JA, Arroyo-Cruz R, Villeda-Navarro M, Mendez-Mejia JA.
Toxicol In Vitro 2009. [Full Text] [PDF]

Reciprocal regulation between M3 muscarinic acetylcholine receptor and protein kinase C-epsilon in ventricular myocytes during myocardial ischemia in rats.
Hang PZ, Zhao J, Wang YP, Sun LH, Zhang Y, Yang LL, et al.
Naunyn Schmiedebergs Arch Pharmacol 2009. [Abstract] [Full Text] [PDF]

Protein kinase C alpha-dependent signaling mediates endometrial cancer cell growth and tumorigenesis.
Haughian JM, Reno EM, Thorne AM, Bradford AP.
Int J Cancer 2009,125:2556-2564. [Abstract] [Full Text] [PDF]

Involvement of protein kinase C and Src tyrosine kinase in acute tolerance to ethanol inhibition of spinal NMDA-induced pressor responses in rats.
Hsieh WK, Lin HH, Lai CC.
Br J Pharmacol 2009. [Abstract] [Full Text] [PDF]

Plasma protein kinase C (PKC)alpha as a biomarker for the diagnosis of cancers.
Kang JH, Asai D, Toita R, Kitazaki H, Katayama Y.
Carcinogenesis 2009.

Protein kinase C alpha and epsilon phosphorylation of troponin and myosin binding protein C reduce Ca2+ sensitivity in human myocardium.
Kooij V, Boontje N, Zaremba R, Jaquet K, dos Remedios C, Stienen GJ, van der Velden J.
Basic Res Cardiol, 2009. [Abstract] [Full Text] [PDF]

Differential fading of inhibitory and excitatory B2 bradykinin receptor responses in rat sympathetic neurons: a role for protein kinase C.
Kosenburger K, Schicker KW, Drobny H, Boehm S.
J Neurochem 2009. [Abstract] [Full Text] [PDF]

The roles of MCP-1 and protein kinase C delta activation in human eosinophilic leukemia EoL-1 cells.
Lee JS, Yang EJ, Kim IS.
Cytokine 2009. [Full Text] [PDF]

Regulation of the substrate preference of p190RhoGAP by protein kinase C-mediated phosphorylation of a phospholipid binding site.
Levay M, Settleman J, Ligeti E.
Biochemistry 2009. [Abstract] [Full Text] [PDF]

Identification of novel cell wall destabilizing antifungal compounds using a conditional Aspergillus nidulans protein kinase C mutant.
Mircus G, Hagag S, Levdansky E, Sharon H, Shadkchan Y, Shalit I, Osherov N.
J Antimicrob Chemother 2009. [Abstract] [Full Text] [PDF]

Supraspinal role of protein kinase C in oxaliplatin-induced neuropathy in rat.
Norcini M, Vivoli E, Galeotti N, Bianchi E, Bartolini A, Ghelardini C.
Pain 2009. [Full Text] [PDF]

Tumor necrosis factor-alpha inhibits Schwann cell proliferation by up-regulating Src-suppressed protein kinase C substrate expression.
Tao T, Ji Y, Cheng C, Yang H, Liu H, Sun L, et al.
J Neurochem 2009. [Abstract] [Full Text] [PDF]

Swiprosin-1 is expressed in mast cells and up-regulated through the protein kinase C beta I/eta pathway.
Thylur RP, Kim YD, Kwon MS, Oh HM, Kwon HK, Kim SH, et al.
J Cell Biochem 2009. [Abstract] [Full Text] [PDF]

Effects of ketamine on glucose uptake by glucose transporter type 3 expressed in Xenopus oocytes: The role of protein kinase C.
Tomioka S, Kaneko M, Satomura K, Mikyu T, Nakajo N.
Biochem Biophys Res Commun 2009. [Full Text] [PDF]

The activation of matrix metalloproteinase-2 induced by protein kinase C alpha in decidualization.
Tsai JH, Hwang JM, Ying TH, Shyu JC, Tsai CC, Hsieh YS, et al.
J Cell Biochem 2009. [Abstract] [Full Text] [PDF]

Cell invasion of Yersinia pseudotuberculosis by invasin and YadA requires protein kinase C, phospholipase C-gamma1 and Akt kinase.
Uliczka F, Kornprobst T, Eitel J, Schneider D, Dersch P.
Cell Microbiol 2009. [Abstract] [Full Text] [PDF]

Gamma-aminobutyric acid transporter 1 negatively regulates T cell activation and survival through protein kinase C-dependent signaling pathways.
Wang Y, Luo Q, Xu Y, Feng D, Fei J, Cheng Q, Xu L.
J Immunol 2009. [Abstract] [Full Text] [PDF]

Protein kinase C-inhibiting properties of the losartan metabolite EXP3179 make the difference.
Wenzel P, Schulz E, Munzel T.
Hypertension 2009. [Abstract] [Full Text] [PDF]

Closed-state inactivation in Kv4.3 isoforms is differentially modulated by protein kinase C.
Xie C, Bondarenko VE, Morales MJ, Strauss HC.
Am J Physiol Cell Physiol 2009. [Abstract]

Mediation of protein kinase C zeta in mu-opioid receptor activation for increase of glucose uptake into cultured myoblast C2C12 cells.
Yang TT, Liu IM, Wu HT, Cheng JT.
Neurosci Lett 2009,465:177-180. [Full Text] [PDF]

Protein kinase Cdelta stimulates proteasome-dependent degradation of C/EBPalpha during apoptosis induction of leukemic cells.
Zhao M, Duan XF, Zhao XY, Zhang B, Lu Y, Liu W, et al.
PLoS One 2009. [Abstract] [Full Text] [PDF]

Postischemic PKC activation rescues retrograde and anterograde long-term memory
Miao-Kun Sun, Jarin Hongpaisan, and Daniel L. Alkon
PNAS, Aug 2009; 106: 14676 - 14680. [Abstract] [Full Text] [PDF]

PKC Differentially Translocates during Spaced and Massed Training in Aplysia
Carole A. Farah, Daniel Weatherill, Tyler W. Dunn, and Wayne S. Sossin
J. Neurosci., Aug 2009; 29: 10281 - 10286. [Abstract] [Full Text] [PDF]

Modulation of ileal apical Na+-dependent bile acid transporter ASBT by protein kinase C
Zaheer Sarwar, Fadi Annaba, Alka Dwivedi, Seema Saksena, Ravinder K. Gill, and Waddah A. Alrefai
Am J Physiol Gastrointest Liver Physiol. 2009; 297:G532-G538. [Abstract]

Plasma protein kinase C (PKC) alpha as a biomarker for the diagnosis of cancers
Jeong-Hun Kang, Daisuke Asai, Riki Toita, Hirotaro Kitazaki, and Yoshiki Katayama
Carcinogenesis. published 26 August 2009, 10.1093/carcin/bgp210 [Abstract] [PDF]

Etoposide Induces Protein Kinase C delta- and Caspase-3-Dependent Apoptosis in Neuroblastoma Cancer Cells
Travis W. Day, Ching-Huang Wu, and Ahmad R. Safa
Mol. Pharmacol. 2009; 76:632-640. [Abstract]

{gamma}-Aminobutyric Acid Transporter 1 Negatively Regulates T Cell Activation and Survival through Protein Kinase C-Dependent Signaling Pathways
Ying Wang, Qingqiong Luo, Yan Xu, Dechun Feng, Jian Fei, Qi Cheng, and Lingyun Xu
J. Immunol. 2009; 183:3488-3495. [Abstract] [Full Text] [PDF]

PPAR{beta}/{delta} Agonists Modulate Platelet Function via a Mechanism Involving PPAR Receptors and Specific Association/Repression of PKC{alpha}
Ferhana Y. Ali, Matthew G. Hall, Beatrice Desvergne, Timothy D. Warner, and Jane A. Mitchell
Arterioscler. Thromb. Vasc. Biol. published 20 August 2009, 10.1161/ATVBAHA.109.193367 [Abstract] [PDF]

EGFR-PLC{gamma}1 signaling mediates high glucose-induced PKCβ1-Akt activation and collagen I upregulation in mesangial cells
D. Wu, F. Peng, B. Zhang, A. J. Ingram, D. J. Kelly, R. E. Gilbert, B. Gao, S. Kumar, and J. C. Krepinsky
Am J Physiol Renal Physiol. 2009; 297:F822-F834. [Abstract]

PKC Phosphorylation of Titin's PEVK Element. A Novel and Conserved Pathway for Modulating Myocardial Stiffness
Carlos Hidalgo, Bryan Hudson, Julius Bogomolovas, Yi Zhu, Brian Anderson, Marion Greaser, Siegfried Labeit, and Henk Granzier
Circ. Res. published 13 August 2009, 10.1161/CIRCRESAHA.109.198465 [Abstract] [PDF]

Sustained Receptor Stimulation Leads to Sequestration of Recycling Endosomes in a Classical Protein Kinase C- and Phospholipase D-dependent Manner
Jolanta Idkowiak-Baldys, Aleksander Baldys, John R. Raymond, and Yusuf A. Hannun
J. Biol. Chem. 2009; 284:22322-22331. [Abstract]

GPD1L LINKS REDOX STATE TO CARDIAC EXCITABILITY BY PKC-DEPENDENT PHOSPHORYLATION OF THE NA CHANNEL SCN5A
Carmen R valdivia, Kazuo Ueda, Michael J. Ackerman, and Jonathan C. Makielski
Am J Physiol Heart Circ Physiol. published 7 August 2009, 10.1152/ajpheart.00513.2009 [Abstract]

Mechanoregulation of BK channel activity in the mammalian cortical collecting duct (CCD): role of protein kinases A and C
Wen Liu, Yuan Wei, Peng Sun, Wen-Hui Wang, Thomas R Kleyman, and Lisa M. Satlin
Am J Physiol Renal Physiol. published 5 August 2009, 10.1152/ajprenal.90685.2008 [Abstract]

Protein Kinase C{gamma} Mediates Regulation of Proliferation by the Serotonin 5-Hydroxytryptamine Receptor 2B
Mira M. Wouters, Jaime L. Roeder, Vivek S. Tharayil, Jennifer E. Stanich, Peter R. Strege, Sha Lei, Michael R. Bardsley, Tamas Ordog, Simon J. Gibbons, and Gianrico Farrugia
J. Biol. Chem. 2009; 284:21177-21184. [Abstract]

Neurotrophins induce neuregulin release through PKC delta activation
Raymond M. Esper and Jeffrey A. Loeb
J. Biol. Chem. published 31 July 2009, 10.1074/jbc.M109.002915 [Abstract] [PDF]