June 2009
Relaxin alters cardiac myofilament function through a PKC-dependent
pathway
Erynn E. Shaw, Philip Wood, Justyna Kulpa, Feng Hua Yang, Alastair J. Summerlee,
and W. Glen Pyle
Am J Physiol Heart Circ Physiol. 2009; 297:H29-H36.
[Abstract] [Full
Text] [PDF]
Periadventitial adipose tissue impairs coronary endothelial function
via PKC-モ-dependent phosphorylation of nitric oxide synthase
Gregory A. Payne, H. Glenn Bohlen, Ü. Deniz Dincer, Léna Borbouse, and Johnathan
D. Tune
Am J Physiol Heart Circ Physiol. 2009; 297:H460-H465.
[Abstract] [Full
Text] [PDF]
Phosphorylation of endothelial nitric oxide synthase by atypical PKC
contributes to angiopoietin-1-dependent inhibition of VEGF-induced endothelial
permeability in vitro
Malika Oubaha and Jean-Philippe Gratton
Blood. published 29 June 2009, 10.1182/blood-2008-12-196584
[Abstract] [PDF]
Protein kinase C
,
a protein causative for dominant ataxia, negatively regulates nuclear import of
recessive-ataxia-related aprataxin
Hirohide Asai, Makito Hirano, Keiji Shimada, Takao Kiriyama, Yoshiko Furiya,
Masanori Ikeda, Takaaki Iwamoto, Toshio Mori, Kazuto Nishinaka, Noboru Konishi,
Fukashi Udaka, and Satoshi Ueno
Hum. Mol. Genet. published 26 June 2009, 10.1093/hmg/ddp298
[Abstract] [PDF]
Serine proteases decrease intestinal epithelial ion permeability by
activation of protein kinase C
Veronica A. Swystun, Bernard Renaux, France Moreau, Shoubin Wen, Michael A.
Peplowski, Morley D. Hollenberg, and Wallace K. MacNaughton
Am J Physiol Gastrointest Liver Physiol. 2009; 297:G60-G70.
[Abstract] [Full
Text] [PDF]
GnRH Stimulates Expression of PACAP in the Pituitary Gonadotropes via
Both the PKA and PKC Signaling Systems
Constance M. Grafer, Robin Thomas, Litsa Lambrakos, Ignacio Montoya, Sheryl
White, and Lisa M. Halvorson
Mol. Endocrinol. 2009; 23:1022-1032.
[Abstract] [Full
Text] [PDF]
Protein
Kinase C
,
but Not PKC
or PKC
,
Regulates Contractility and Heart Failure Susceptibility. Implications for
Ruboxistaurin As a Novel Therapeutic Approach
Qinghang Liu, Xiongwen Chen, Scott M. MacDonnell, Evangelia G. Kranias, John N.
Lorenz, Michael Leitges, Steven R. Houser, and Jeffery D. Molkentin
Circ. Res. published 25 June 2009, 10.1161/CIRCRESAHA.109.195313
[Abstract] [PDF]
Excretory-secretory
products from Paragonimus westermani increase nitric oxide production in
microglia in PKC-dependent and -independent manners.
Youngnam Jin, In Young Choi, Chunsook Kim, Suyoung Hong, and Won-Ki Kim
Neurosci Res. 2009. [MEDLINE
Citation]
Protein
kinase Cgamma mediates regulation of proliferation by the serotonin 5-HT2B
receptor.
Mira M Wouters, Jaime L Roeder, Vivek S Tharayil, Jennifer E Stanich, Peter R
Strege, Sha Lei, Michael R Bardsley, Tamas Ordog, Simon J Gibbons, and Gianrico
Farrugia
J Biol Chem. 2009. [MEDLINE
Citation]
Role of protein kinase C delta in angiotensin II induced cardiac
fibrosis.
Vishnu Chintalgattu and Laxmansa C Katwa
Biochem Biophys Res Commun. 2009. [MEDLINE
Citation]
Mechanisms of Protein Kinase C Signaling in the Modulation of
3',5'-Cyclic Adenosine Monophosphate-Mediated Steroidogenesis in Mouse Gonadal
Cells
Pulak R. Manna, Ilpo T. Huhtaniemi, and Douglas M. Stocco
Endocrinology. 2009; 150:3308-3317.
[Abstract] [Full
Text] [PDF]
Protein Kinase C
Activates RelA/p65 and Nuclear Factor-
B
Signaling in Response to Tumor Necrosis Factor-
Zheng-Guang Lu, Hanshao Liu, Tomoko Yamaguchi, Yoshio Miki, and Kiyotsugu
Yoshida
Cancer Res. published 23 June 2009, 10.1158/0008-5472.CAN-08-4786
[Abstract]
Etoposide Induces Protein Kinase C
-
and Caspase-3-dependent Apoptosis in Neuroblastoma Cancer Cells
Travis W. Day, Ching-Huang Wu, and Ahmad R. Safa
Mol. Pharmacol. published 23 June 2009, 10.1124/mol.109.054999
[Abstract] [PDF]
PKC-
Modulates the Strength of T Cell Responses by Targeting Cbl-b for Ubiquitination
and Degradation
Sci. Signal., Vol. 2, Issue 76, pp. ra30
[Summary]
[Abstract]
[Full Text
Rescue of atypical protein kinase C in epithelia by the cytoskeleton
and Hsp70 family chaperones
Anastasia Mashukova, Andrea S. Oriolo, Flavia A. Wald, M. Llanos Casanova,
Cornelia Kröger, Thomas M. Magin, M. Bishr Omary, and Pedro J.I. Salas
J. Cell Sci. published 23 June 2009, 10.1242/jcs.046979
[Abstract] [PDF]
An adhesion-independent, aPKC-dependent function for cadherins in
morphogenetic movements
Karla Seifert, Hady Ibrahim, Torben Stodtmeister, Rudolf Winklbauer, and Carien
M. Niessen
J. Cell Sci. published 23 June 2009, 10.1242/jcs.042796
[Abstract] [PDF]
Activation
of Protein Kinase C
by EPAC1 Is Required for the ERK- and CCAAT/Enhancer-binding Protein モ-dependent
Induction of the SOCS-3 Gene by Cyclic AMP in COS1 Cells
Gillian Borland, Rebecca J. Bird, Timothy M. Palmer, and Stephen J. Yarwood
J. Biol. Chem. 2009; 284:17391-17403.
[Abstract] [Full
Text] [PDF]
Phosphorylation of
6-Tubulin
by Protein Kinase C
Activates Motility of Human Breast Cells
Thushara P. Abeyweera, Xiangyu Chen, and Susan A. Rotenberg
J. Biol. Chem. 2009; 284:17648-17656.
[Abstract] [Full
Text] [PDF]
Activation of Protein Kinase C
by EPAC1 Is Required for the ERK- and CCAAT/Enhancer-binding Protein モ-dependent
Induction of the SOCS-3 Gene by Cyclic AMP in COS1 Cells
Gillian Borland, Rebecca J. Bird, Timothy M. Palmer, and Stephen J. Yarwood
J. Biol. Chem. 2009; 284:17391-17403.
[Abstract] [Full
Text] [PDF]
Phosphorylation of
6-Tubulin
by Protein Kinase C
Activates Motility of Human Breast Cells
Thushara P. Abeyweera, Xiangyu Chen, and Susan A. Rotenberg
J. Biol. Chem. 2009; 284:17648-17656.
[Abstract] [Full
Text] [PDF]
Correlation between Apical Localization of Abcc2/Mrp2 and
Phosphorylation Status of Ezrin in Rat Intestine
Takafumi Nakano, Shuichi Sekine, Kousei Ito, and Toshiharu Horie
Drug Metab. Dispos. 2009; 37:1521-1527.
[Abstract] [Full
Text] [PDF]
Transforming Growth Factor-モ Promotes Recruitment of Bone Marrow
Cells and Bone Marrow-derived Mesenchymal Stem Cells through Stimulation of
MCP-1 Production in Vascular Smooth Muscle Cells
Fan Zhang, Shirling Tsai, Kaori Kato, Dai Yamanouchi, Chunjie Wang, Shahin Rafii,
Bo Liu, and K. Craig Kent
J. Biol. Chem. 2009; 284:17564-17574.
[Abstract] [Full
Text] [PDF]
Ca2+-independent contraction of longitudinal ileal smooth
muscle is potentiated by a zipper-interacting protein kinase pseudosubstrate
peptide
Eikichi Ihara, Lori Moffat, Meredith Alison Borman, Jennifer E Amon, Michael P.
Walsh, and Justin A. MacDonald
Am J Physiol Gastrointest Liver Physiol. published 18 June 2009,
10.1152/ajpgi.00112.2009
[Abstract] [PDF]
Abscisic Acid Released by Human Monocytes Activates Monocytes and
Vascular Smooth Muscle Cell Responses Involved in Atherogenesis
Mirko Magnone, Santina Bruzzone, Lucrezia Guida, Gianluca Damonte, Enrico Millo,
Sonia Scarfì, Cesare Usai, Laura Sturla, Domenico Palombo, Antonio De Flora, and
Elena Zocchi
J. Biol. Chem. 2009; 284:17808-17818.
[Abstract] [Full
Text] [PDF]
The potent protein kinase C selective inhibitor AEB071 (Sotrastaurin)represents
a new class of immunosuppressive agents affecting early T cell activation.
Jean-Pierre Evenou, Juergen Wagner, Gerhard Zenke, Volker Brinkmann, Kathrin
Wagner, Jiri Kovarik, Karl Welzenbach, Gabriele Weitz-Schmidt, Christine
Guntermann, Harry Towbin, Sylvain Cottens, Sandra Kaminski, Thomas Letschka,
Christina Lutz-Nicoladoni, Thomas Gruber, Natascha Hermann-Kleiter, Nikolaus
Thuille, and Gottfried Baier
J Pharmacol Exp Ther. 2009. [MEDLINE
Citation]
Direct Chronic Effect of Steroid Hormones in Attenuating Uterine
Arterial Myogenic Tone. Role of Protein Kinase C/Extracellular Signal-Regulated
Kinase 1/2.
Daliao Xiao, Xiaohui Huang, Shumei Yang, and Lubo Zhang
Hypertension. 2009. [MEDLINE
Citation]
Protein kinase C epsilon activation delays neuronal depolarization
during cardiac arrest in the euthermic arctic ground squirrel.
Kunjan R Dave, R Anthony Defazio, Ami P Raval, Oleksandr Dashkin, Isabel Saul,
Kimberly E Iceman, Miguel A Perez-Pinzon, and Kelly L Drew
J Neurochem. 2009. [MEDLINE
Citation]
Atypical protein kinase C activity is required for extracellular
matrix degradation and invasion by Src-transformed cells.
Elena M Rodriguez, Elizabeth E Dunham, and G Steven Martin
J Cell Physiol. 2009. [MEDLINE
Citation]
Role of protein kinase C in NADPH oxidase derived O(2)(.-)-mediated
regulation of K(V) - LVOCC axis under U46619 induced increase in [Ca(2+)](i) in
pulmonary smooth muscle cells.
Sajal Chakraborti, Animesh Chaudhury, Pulak Kar, Partha Das, Soni Shaikh,
Soumitra Roy, and Tapati Chakraborti
Arch Biochem Biophys. 2009. [MEDLINE
Citation]
Role of protein kinase C in advanced glycation end products-induced
epithelial-mesenchymal transition in renal proximal tubular epithelial cells.
S Ge, R Zeng, Y Luo, L Liu, H Wei, J Zhang, H Zhou, and G Xu
J Huazhong Univ Sci Technolog Med Sci. 2009; 29: 281. [MEDLINE
Citation]
Design, Synthesis, and Investigation of Protein Kinase C Inhibitors:
Total Syntheses of (+)-Calphostin D, (+)-Phleichrome, Cercosporin, and New
Photoactive Perylenequinones.
Barbara J Morgan, Sangeeta Dey, Steven W Johnson, and Marisa C Kozlowski
J Am Chem Soc. 2009. [MEDLINE
Citation]
Synergistic anti-tumor efficacy of lovastatin and protein kinase
C-beta inhibitor in hepatocellular carcinoma.
W Kim, JH Yoon, JR Kim, IJ Jang, YJ Bang, YJ Kim, and HS Lee
Cancer Chemother Pharmacol. 2009; 64: 497. [MEDLINE
Citation]
Antiapoptotic effects of vasopressin in the neuronal cell line H32
involve protein kinase C alpha and beta.
Jun Chen, Ying Liu, Jae-Won Soh, and Greti Aguilera
J Neurochem. 2009. [MEDLINE
Citation]
Adenoprotection of the Heart Involves Phospholipase C-Induced
Activation and Translocation of PKC{varepsilon} to RACK2 in Adult Rat and Mouse.
Richard A Fenton, Satoshi Komatsu, Mitsuo Ikebe, Lynne G Shea, and James G
Dobson Jr
Am J Physiol Heart Circ Physiol. 2009. [MEDLINE
Citation]
A new mechanism of SOX9 action to regulate PKC{alpha} expression in
the intestine epithelium.
Sebastien Dupasquier, Rana Abdel-Samad, Robert I Glazer, Pauline Bastide,
Philippe Jay, Dominique Joubert, Vincent Cavailles, Philippe Blache, and Corinne
Quittau-Prevostel
J Cell Sci. 2009. [MEDLINE
Citation]
Activation of Intracellular Signaling Pathways by the MCMV GPCR M33
Occurs Via PLC-{beta}/PKC Dependent and Independent Mechanisms.
Joseph D Sherrill, Melissa P Stropes, Olivia D Schneider, Diana E Koch, Fabiola
M Bittencourt, Jeanette L C Miller, and William E Miller
J Virol. 2009. [MEDLINE
Citation]
PKC Delta and Epsilon in Drug Targeting and Therapeutics.
T Yonezawa, R Kurata, M Kimura, and H Inoko
Recent Pat DNA Gene Seq. 2009; 3: 96. [MEDLINE
Citation]
PKC isoforms differentially phosphorylate Cav1.2 alpha1c.
Lin Yang, Darshan Doshi, John P Morrow, Alexander Katchman, Xiang Chen, and
Steven O Marx
Biochemistry. 2009. [MEDLINE
Citation]
DHEA improves impaired activation of Akt and PKC zeta/lambda-GLUT4
pathway in skeletal muscle and improves hyperglycemia in streptozotocin-induced
diabetes rats.
Koji Sato, Motoyuki Iemitsu, Katsuji Aizawa, and Ryuichi Ajisaka
Acta Physiol (Oxf). 2009. [MEDLINE
Citation]
Phosphorylation of the influenza A virus protein PB1-F2 by PKC is
crucial for apoptosis promoting functions in monocytes.
David Mitzner, Sabine Eva Dudek, Nicole Studtrucker, Darisuren Anhlan, Igor
Mazur, Josef Wissing, Lothar Jansch, Ludmilla Wixler, Karsten Bruns, Alok
Sharma, Victor Wray, Peter Henklein, Stephan Ludwig, and Ulrich Schubert
Cell Microbiol. 2009. [MEDLINE
Citation]
Direct Chronic Effect of Steroid Hormones in Attenuating Uterine
Arterial Myogenic Tone. Role of Protein Kinase C/Extracellular Signal-Regulated
Kinase 1/2.
Daliao Xiao, Xiaohui Huang, Shumei Yang, and Lubo Zhang
Hypertension. 2009. [MEDLINE
Citation]
Inhibition of protein kinase C in diabetic nephropathy—where do we
stand?
Jan Menne, Matthias Meier, Joon-Keun Park, and Hermann Haller
Nephrol. Dial. Transplant. 2009; 24:2021-2023.
[Extract] [Full
Text] [PDF]
Direct Chronic Effect of Steroid Hormones in Attenuating Uterine
Arterial Myogenic Tone. Role of Protein Kinase C/Extracellular Signal–Regulated
Kinase 1/2
Daliao Xiao, Xiaohui Huang, Shumei Yang, and Lubo Zhang
Hypertension. published 15 June 2009, 10.1161/HYPERTENSIONAHA.109.
1-AMP-Activated
Protein Kinase Regulates Hypoxia-Induced Na,K-ATPase Endocytosis via Direct
Phosphorylation of Protein Kinase C
Galina A. Gusarova, Laura A. Dada, Aileen M. Kelly, Chaya Brodie, Lee A. Witters,
Navdeep S. Chandel, and Jacob I. Sznajder
Mol. Cell. Biol. 2009; 29:3455-3464.
[Abstract] [Full
Text] [PDF]
Activation of Protein Kinase C
Is Necessary for Sorting the PDGF モ-Receptor to Rab4a-dependent Recycling
Carina Hellberg, Christian Schmees, Susann Karlsson, Aive Åhgren, and Carl-Henrik
Heldin
Mol. Biol. Cell. 2009; 20:2856-2863.
[Abstract] [Full
Text] [PDF]
Sustained Receptor Stimulation Leads to Sequestration of Recycling
Endosomes in a cPKC and PLD-Dependent Manner
Jolanta Idkowiak-Baldys, Aleksander Baldys, John R. Raymond, and Yusuf A. Hannun
J. Biol. Chem. published 11 June 2009, 10.1074/jbc.M109.026765
[Abstract] [PDF]
Protein kinase C
(PKC
)
expression as a potential diagnostic marker for KIT-negative GIST
D. A. Braggio, S. Romano, I. A. Small, F. A. Soares, C. G. Ferreira, and D. P.
Guimarães
ASCO Meeting Abstracts. 2009; 27:10561.
[Abstract]
Steel factor enhances supraoptimal antigen-induced IL-6 production
from mast cells via activation of protein kinase C-beta.
K Fehrenbach, E Lessmann, CN Zorn, M Kuhny, G Grochowy, G Krystal, M Leitges,
and M Huber
J Immunol. 2009; 182: 7897. [MEDLINE
Citation]
Role of protein kinase C in regulation of Na+- and K +-dependent
ATPase activity and pump function in corneal endothelial cells.
S Hatou, M Yamada, H Mochizuki, and T Nishida
Jpn J Ophthalmol. 2009; 53: 235. [MEDLINE
Citation]
Periadventitial adipose tissue impairs coronary endothelial function
via PKC-{beta} dependent phosphorylation of nitric oxide synthase.
Gregory A Payne, H Glenn Bohlen, U Deniz Dincer, Lena Borbouse, and Johnathan D
Tune
Am J Physiol Heart Circ Physiol. 2009. [MEDLINE
Citation]
Role of protein kinase C in regulation of Na+- and K +-dependent
ATPase activity and pump function in corneal endothelial cells.
S Hatou, M Yamada, H Mochizuki, and T Nishida
Jpn J Ophthalmol. 2009; 53: 235. [MEDLINE
Citation]
Pivotal
Advance: PKCzeta is required for migration of macrophages
Hua Guo, Yongjie Ma, Baogang Zhang, Baocun Sun, Ruifang Niu, Guoguang Ying, and
Ning Zhang
J. Leukoc. Biol. 2009; 85:911-918.
[Abstract] [Full
Text] [PDF]
Activation
of Intracellular Signaling Pathways by the MCMV GPCR M33 Occurs Via PLC-
/PKC
Dependent and Independent Mechanisms
Joseph D. Sherrill, Melissa P. Stropes, Olivia D. Schneider, Diana E. Koch,
Fabiola M. Bittencourt, Jeanette L.C. Miller, and William E. Miller
J. Virol. published 3 June 2009, 10.1128/JVI.02116-08
[Abstract] [PDF]
The potent
protein kinase C selective inhibitor AEB071 (Sotrastaurin)represents a new class
of immunosuppressive agents affecting early T cell activation
Jean-Pierre Evenou, Juergen Wagner, Gerhard Zenke, Volker Brinkmann, Kathrin
Wagner, Jiri Kovarik, Karl Welzenbach, Gabriele Weitz-Schmidt, Christine
Guntermann, Harry Towbin, Sylvain Cottens, Sandra Kaminski, Thomas Letschka,
Christina Lutz-Nicoladoni, Thomas Gruber, Natascha Hermann-Kleiter, Nikolaus
Thuille, and Gottfried Baier
J. Pharmacol. Exp. Ther. published 2 June 2009,
10.1124/jpet.109.153205
[Abstract] [PDF]