Enhancement of calcium transport in Caco-2 monolayer through PKC-dependent Ca_v1.3-mediated transcellular and rectifying paracellular pathways by prolactin
Narongrit Thongon, La-iad Nakkrasae, Jirawan Thongbunchoo, Nateetip Krishnamra, and Narattaphol Charoenphandhu
Am J Physiol Cell Physiol. 2009; 296:C1373-C1382.  [Abstract] [Full Text] [PDF]

FXYD1 phosphorylation in vitro and in adult rat cardiac myocytes: threonine 69 is a novel substrate for protein kinase C
William Fuller, Jacqueline Howie, Linda M. McLatchie, Roberta J. Weber, C. James Hastie, Kerry Burness, Davor Pavlovic, and Michael J. Shattock
Am J Physiol Cell Physiol. 2009; 296:C1346-C1355.  [Abstract] [Full Text] [PDF]

Sprouty2 interacts with protein kinase C {delta} and disrupts phosphorylation of protein kinase D 1.
Soah Yee Chow, Chye Yun Yu, and Graeme R Guy
J Biol Chem. 2009. [MEDLINE Citation]

Nefiracetam activation of CaM kinase II and Protein kinase C mediated by NMDA and metabotropic glutamate receptors in olfactory bulbectomized mice.
Shigeki Moriguchi, Feng Han, Norifumi Shioda, Yui Yamamoto, Takeharu Nakajima, Osamu Nakagawasai, Takeshi Tadano, Jay Z Yeh, Toshio Narahashi, and Kohji Fukunaga
J Neurochem. 2009. [MEDLINE Citation]

Titanium implants alter endothelial function and vasoconstriction via a protein kinase C-regulated pathway.
Rong Sen Yang, Huei Ping Tzeng, Feng Ming Ho, Chia Chi Chuang, Bo Lin Chen, Chun-Fa Huang, Ya-Wen Chen, Ruei Ming Chen, and Shing Hwa Liu
Acta Biomater. 2009. [MEDLINE Citation]

Synthesis and evaluation of novel 7-azaindazolyl-indolyl-maleimide derivatives as antitumor agents and protein kinase C inhibitors.
Qing Ye, Ji Cao, Xinglu Zhou, Dan Lv, Qiaojun He, Bo Yang, and Yongzhou Hu
Bioorg Med Chem. 2009. [MEDLINE Citation]

Inhibition of superoxide anion generation by CHS-111 via blockade of the p21-activated kinase, protein kinase B/Akt and protein kinase C signaling pathways in rat neutrophils.
Ling-Chu Chang, Ruey-Hseng Lin, Li-Jiau Huang, Chi-Sen Chang, Sheng-Chu Kuo, and Jih-Pyang Wang
Eur J Pharmacol. 2009. [MEDLINE Citation]

A Simple Analogue of Tumor-Promoting Aplysiatoxin Is an Antineoplastic Agent Rather Than a Tumor Promoter: Development of a Synthetically Accessible Protein Kinase C Activator with Bryostatin-like Activity.
Yu Nakagawa, Ryo C Yanagita, Naoko Hamada, Akira Murakami, Hideyuki Takahashi, Naoaki Saito, Hiroshi Nagai, and Kazuhiro Irie
J Am Chem Soc. 2009. [MEDLINE Citation]

Common Polymorphism in the Phosphatase PHLPP2 Results in Reduced Regulation of Akt and Protein Kinase C
John Brognard, Matthew Niederst, Gloria Reyes, Noel Warfel, and Alexandra C. Newton
J. Biol. Chem. 2009; 284:15215-15223.  [Abstract] [Full Text] [PDF]

Knockout of the predominant conventional PKC isoform, PKC, in mouse skeletal muscle does not affect contraction-stimulated glucose uptake
Thomas Elbenhardt Jensen, Stine J. Maarbjerg, Adam J Rose, Michael Leitges, and Erik A. Richter
Am J Physiol Endocrinol Metab. published 19 May 2009, 10.1152/ajpendo.90610.2008  [Abstract] [PDF]

Protein kinase C-β inhibition attenuates the progression of nephropathy in non-diabetic kidney disease
Darren J. Kelly, Amanda J. Edgley, Yuan Zhang, Kerri Thai, Sih Min Tan, Alison J. Cox, Andrew Advani, Kim A. Connelly, Catharine I. Whiteside, and Richard E. Gilbert
Nephrol. Dial. Transplant. 2009; 24:1782-1790.  [Abstract] [Full Text] [PDF]

A 20 amino acid module of PKC{varepsilon} involved in translocation and selective targeting at cell-cell contacts.
Barthelemy Diouf, Alejandra Collazos, Gilles Labesse, Francoise Macari, Armelle Choquet, Philippe Clair, Cecile Gauthier-Rouviere, Nathalie C Guerineau, Philippe Jay, Frederic Hollande, and Dominique Joubert
J Biol Chem. 2009. [MEDLINE Citation]

Endothelin I and angiotensin II inhibit arterial voltage-gated K+ channels through different PKC isoenzymes.
Richard D Rainbow, Robert I Norman, Diane E Everitt, Jennifer L Brignell, Noel W Davies, and Nicholas B Standen
Cardiovasc Res. 2009. [MEDLINE Citation]

Relaxin alters cardiac myofilament function through a PKC-dependent pathway.
Erynn E Shaw, Philip Wood, Justyna Kulpa, Feng Hua Yang, Alastair J Summerlee, and W Glen Pyle
Am J Physiol Heart Circ Physiol. 2009. [MEDLINE Citation]

Formation of endothelial lumens requires a coordinated PKC{epsilon}-, Src-, Pak- and Raf-kinase-dependent signaling cascade downstream of Cdc42 activation.
Wonshill Koh, Kamakshi Sachidanandam, Amber N Stratman, Anastasia Sacharidou, Anne M Mayo, Eric A Murphy, David A Cheresh, and George E Davis
J Cell Sci. 2009. [MEDLINE Citation]

PKC epsilon has an alcohol binding site in its second cysteine rich regulatory domain.
Joydip Das, Satyabrata Pany, Ghazi M Rahman, and Simon J Slater
Biochem J. 2009. [MEDLINE Citation]

Differential involvement of PKC-Dependent MAPKs activation in Lipopolysaccharide-Induced AP-1 expression in human tracheal smooth muscle cells.
Wei-Ning Lin, Shue-Fen Luo, Chih-Chung Lin, Li-Der Hsiao, and Chuen-Mao Yang
Cell Signal. 2009. [MEDLINE Citation]

Bee venom suppresses LPS-mediated NO/iNOS induction through inhibition of PKC-alpha expression.
KG Lee, HJ Cho, YS Bae, KK Park, JY Choe, IK Chung, M Kim, JH Yeo, KH Park, YS Lee, CH Kim, and YC Chang
J Ethnopharmacol. 2009; 123: 15. [MEDLINE Citation]

Activation of corticotropin-releasing factor 2 receptor inhibits Purkinje neuron P-type calcium currents via G(o)alpha-dependent PKC eposilon pathway.
Jin Tao, Yuan Zhang, Hua Huang, and Xinghong Jiang
Cell Signal. 2009. [MEDLINE Citation]

Phorbol 12-myristate 13-acetate potentiation of N-Methyl-D-aspartate-induced currents in primary cultured cerebellar granule cells is mediated by Protein Kinase C{alpha}
Jason C Reneau, Mary E Reyland, Jonathan Phillips, Carissa Kindy, and Roseanna Lisa Popp
J Pharmacol Exp Ther. 2009. [MEDLINE Citation]

Formation of endothelial lumens requires a coordinated PKC-, Src-, Pak- and Raf-kinase-dependent signaling cascade downstream of Cdc42 activation
Wonshill Koh, Kamakshi Sachidanandam, Amber N. Stratman, Anastasia Sacharidou, Anne M. Mayo, Eric A. Murphy, David A. Cheresh, and George E. Davis
J. Cell Sci. published 12 May 2009, 10.1242/jcs.045799  [Abstract] [PDF]

Protein Kinase D Mediates Mitogenic Signaling by G_q-coupled Receptors through Protein Kinase C-independent Regulation of Activation Loop Ser⁷⁴⁴ and Ser⁷⁴⁸ Phosphorylation
James Sinnett-Smith, Rodrigo Jacamo, Robert Kui, YunZu M. Wang, Steven H. Young, Osvaldo Rey, Richard T. Waldron, and Enrique Rozengurt
J. Biol. Chem. 2009; 284:13434-13445.  [Abstract] [Full Text] [PDF]

Endothelin I and angiotensin II inhibit arterial voltage-gated K⁺ channels through different PKC isoenzymes
Richard D. Rainbow, Robert I. Norman, Diane E. Everitt, Jennifer L. Brignell, Noel W. Davies, and Nicholas B. Standen
Cardiovasc Res. published 8 May 2009, 10.1093/cvr/cvp143  [Abstract] [PDF]

Phosphorylation of connexin-43 at serine 262 promotes a cardiac injury-resistant state
Wattamon Srisakuldee, Maya M. Jeyaraman, Barbara E. Nickel, Stéphane Tanguy, Zhisheng Jiang, and Elissavet Kardami
Cardiovasc Res. published 7 May 2009, 10.1093/cvr/cvp142  [Abstract] [PDF]

Activation of protein kinase C alpha by EPAC1 is required for the ERK- and C/EBPbeta-dependent induction of the SOCS-3 gene by cyclic AMP in COS1 cells
Gillian Borland, Rebecca J. Bird, Timothy M. Palmer, and Stephen J. Yarwood
J. Biol. Chem. published 7 May 2009, 10.1074/jbc.M109.015370  [Abstract] [PDF]

Protein kinase C signalling during miracidium to mother sporocyst development in the helminth parasite, Schistosoma mansoni.
Marthe H R Ludtmann, David Rollinson, Aidan M Emery, and Anthony J Walker
Int J Parasitol. 2009. [MEDLINE Citation]

The protein kinase C agonist PEP005 increases NF-kappaB expression, induces differentiation and increases constitutive chemokine release by primary acute myeloid leukaemia cells.
Astrid Marta Olsnes, Elisabeth Ersvaer, Anita Ryningen, Kristin Paulsen, Peter Hampson, Janet M Lord, Bjorn Tore Gjertsen, Einar Klaeboe Kristoffersen, and Oystein Bruserud
Br J Haematol. 2009. [MEDLINE Citation]

Interactions between mitogen-activated protein kinase and protein kinase C signaling during oocyte maturation and fertilization in a marine worm.
Stephen A Stricker
Mol Reprod Dev. 2009. [MEDLINE Citation]

Receptor-induced phasic activity of newborn mouse bladders is inhibited by protein kinase C and involves T-type Ca channels.
Mari Ekman, Karl-Erik Andersson, and Anders Arner
BJU Int. 2009. [MEDLINE Citation]

Acute memory phase of sevoflurane preconditioning is associated with sustained translocation of protein kinase C-alpha and ϵ, but not delta, in isolated guinea pig hearts.
Chika Okusa, Masami Miyamae, Shingo Sugioka, Kazuhiro Kaneda, Yoshitaka Inamura, Anna Onishi, Naochika Domae, Junichiro Kotani, and Vincent M Figueredo
Eur J Anaesthesiol. 2009. [MEDLINE Citation]

Deletion of PKC{varepsilon} selectively enhances the amplifying pathways of glucose-stimulated insulin secretion via increased lipolysis in mouse {beta}-cells.
James Cantley, James G Burchfield, Gemma L Pearson, Carsten Schmitz-Peiffer, Michael Leitges, and Trevor J Biden
Diabetes. 2009. [MEDLINE Citation]

Chronic hypoxia increases pressure-dependent myogenic tone of the uterine artery in pregnant sheep: role of ERK/PKC pathway.
Katherine Chang, Daliao Xiao, Xiaohui Huang, Lawrence D Longo, and Lubo Zhang
Am J Physiol Heart Circ Physiol. 2009. [MEDLINE Citation]

Searching for Disease Modifiers-PKC Activation and HDAC Inhibition-A Dual Drug Approach to Alzheimer's Disease that Decreases Abeta Production while Blocking Oxidative Stress.
Alan P Kozikowski, Yihua Chen, Tapadar Subhasish, Nancy E Lewin, Peter M Blumberg, Zhenyu Zhong, Melissa A D'Annibale, Weng-Long Wang, Yong Shen, and Brett Langley
ChemMedChem. 2009. [MEDLINE Citation]

Tamoxifen inhibits tumor cell invasion and metastasis in mouse melanoma through suppression of PKC/MEK/ERK and PKC/PI3K/Akt pathways.
Hiroshi Matsuoka, Masanobu Tsubaki, Yuzuru Yamazoe, Mitsuhiko Ogaki, Takao Satou, Tatsuki Itoh, Takashi Kusunoki, and Shozo Nishida
Exp Cell Res. 2009. [MEDLINE Citation]

The modulation of aquaporin-4 by using PKC-activator (phorbol myristate acetate) and V1a receptor antagonist (SR49059) following middle cerebral artery occlusion/reperfusion in the rat.
K Okuno, K Taya, CR Marmarou, P Ozisik, G Fazzina, A Kleindienst, S Gulsen, and A Marmarou
Acta Neurochir Suppl. 2008; 102: 431. [MEDLINE Citation]

Paclitaxel and vinorelbine, evoked the release of substance P from cultured rat dorsal root ganglion cells through different PKC isoform-sensitive ion channels.
Kanako Miyano, He-Bin Tang, Yoki Nakamura, Norimitsu Morioka, Atsuko Inoue, and Yoshihiro Nakata
Neuropharmacology. 2009. [MEDLINE Citation]

The mechanism of HTLV-1 LTR activation by TPA varies in different human T-cell lines: Role of specific PKC isoforms.
Rachel Chamias, Mahmoud Huleihel, and Mordechai Aboud
Leuk Res. 2009. [MEDLINE Citation]

Prenatal cocaine exposure abolished ischemic preconditioning-induced protection in adult male rat hearts: role of PKC
Kurt D. Meyer, Haitao Zhang, and Lubo Zhang
Am J Physiol Heart Circ Physiol. 2009; 296:H1566-H1576.  [Abstract] [Full Text] [PDF]

CapZ dynamics are altered by endothelin-1 and phenylephrine via PIP2- and PKC-dependent mechanisms
Thomas J. Hartman, Jody L. Martin, R. John Solaro, Allen M. Samarel, and Brenda Russell
Am J Physiol Cell Physiol. 2009; 296:C1034-C1039.  [Abstract] [Full Text] [PDF]

Effects of thapsigargin and phenylephrine on calcineurin and protein kinase C signaling functions in cardiac myocytes
Anand Mohan Prasad and Giuseppe Inesi
Am J Physiol Cell Physiol. 2009; 296:C992-C1002.  [Abstract] [Full Text] [PDF]

Rottlerin induces apoptosis via death receptor 5 (DR5) upregulation through CHOP-dependent and PKC -independent mechanism in human malignant tumor cells
Jun Hee Lim, Jong-Wook Park, Kyeong Sook Choi, Yong Bok Park, and Taeg Kyu Kwon
Carcinogenesis. 2009; 30:729-736.  [Abstract] [Full Text] [PDF]

Involvement of Acid β-Glucosidase 1 in the Salvage Pathway of Ceramide Formation
Kazuyuki Kitatani, Kely Sheldon, Vinodh Rajagopalan, Viviana Anelli, Russell W. Jenkins, Ying Sun, Gregory A. Grabowski, Lina M. Obeid, and Yusuf A. Hannun
J. Biol. Chem. 2009; 284:12972-12978.  [Abstract] [Full Text] [PDF]

Acid β-Glucosidase 1 Counteracts p38-dependent Induction of Interleukin-6: POSSIBLE ROLE FOR CERAMIDE AS AN ANTI-INFLAMMATORY LIPID
Kazuyuki Kitatani, Kely Sheldon, Viviana Anelli, Russell W. Jenkins, Ying Sun, Gregory A. Grabowski, Lina M. Obeid, and Yusuf A. Hannun
J. Biol. Chem. 2009; 284:12979-12988.  [Abstract] [Full Text] [PDF]