April 2009

April 2009

Phosphorylation of $alpha$ 6-tubulin by protein kinase C $alpha$ activates motility of human breast cells
Thushara P. Abeyweera, Xiangyu Chen, and Susan A. Rotenberg
J. Biol. Chem. published 29 April 2009, 10.1074/jbc.M902005200 [Abstract] [PDF]

Permissive action of protein kinase C- ${zeta}$ in insulin-induced CD36- and GLUT4 translocation in cardiac myocytes
Joost J F P Luiken, D Margriet Ouwens, Daphna D J Habets, Gerard C M van der Zon, Will A Coumans, Robert W Schwenk, Arend Bonen, and Jan F C Glatz
J. Endocrinol. 2009; 201:199-209. [Abstract] [Full Text] [PDF]

Protein Kinase C-mediated Phosphorylation and Activation of PDE3A Regulate cAMP Levels in Human Platelets
Roger W. Hunter, Carol MacKintosh, and Ingeborg Hers
J. Biol. Chem. 2009; 284:12339-12348. [Abstract] [Full Text] [PDF]

An Atypical Protein Kinase C (PKC ${zeta}$ ) Plays a Critical Role in Lipopolysaccharide-Activated NF- ${kappa}$ B in Human Peripheral Blood Monocytes and Macrophages
XueSong Huang, Ling-Yu Chen, Astrid M. Doerner, Warren W. Pan, Laura Smith, Shuang Huang, Thomas J. Papadimos, and Zhixing K. Pan
J. Immunol. 2009; 182:5810-5815. [Abstract] [Full Text] [PDF]

Chronic hypoxia increases pressure-dependent myogenic tone of the uterine artery in pregnant sheep: role of ERK/PKC pathway
Katherine Chang, Daliao Xiao, Xiaohui Huang, Lawrence D. Longo, and Lubo Zhang
Am J Physiol Heart Circ Physiol. published 17 April 2009, 10.1152/ajpheart.00090.2009 [Abstract] [PDF]

Perspectives of Protein Kinase C (PKC) Inhibitors as Anti-Cancer Agents.
A Gonelli, C Mischiati, R Guerrini, R Voltan, S Salvadori, and G Zauli
Mini Rev Med Chem. 2009; 9: 498. [MEDLINE Citation]

A PKC-dependent recruitment of MMP-2 controls semaphorin-3A growth-promoting effect in cortical dendrites.
B Gonthier, E Koncina, S Satkauskas, M Perraut, G Roussel, D Aunis, JP Kapfhammer, and D Bagnard
PLoS ONE. 2009; 4: e5099. [MEDLINE Citation]

Loss of Protein Kinase C ${gamma}$ in Knockout Mice and Increased Retinal Sensitivity to Hyperbaric Oxygen
Vladimir V. Yevseyenkov, Satyabrata Das, Dingbo Lin, Lloyd Willard, Harriet Davidson, Ari Sitaramayya, Frank J. Giblin, L. Dang, and Dolores J. Takemoto
Arch Ophthalmol. 2009; 127:500-506. [Abstract] [Full Text] [PDF]

Protein kinase C in heart failure: a therapeutic target?
Suresh Selvaraj Palaniyandi, Lihan Sun, Julio Cesar Batista Ferreira, and Daria Mochly-Rosen
Cardiovasc Res. 2009; 82:229-239. [Abstract] [Full Text] [PDF]

Connexin43 Potentiates Osteoblast Responsiveness to Fibroblast Growth Factor 2 via a Protein Kinase C-Delta/Runx2-dependent Mechanism.
Florence Lima, Corinne Niger, Carla Hebert, and Joseph P Stains
Mol Biol Cell. 2009. [MEDLINE Citation]

FXYD1 PHOSPHORYLATION IN VITRO AND IN ADULT RAT CARDIAC MYOCYTES: THREONINE 69 IS A NOVEL SUBSTRATE FOR PROTEIN KINASE C.
William Fuller, Jacqueline Howie, Linda McLatchie, Roberta Weber, C James Hastie, Kerry Burness, Davor Pavlovic, and Michael Jonathan Shattock
Am J Physiol Cell Physiol. 2009. [MEDLINE Citation]

Gonadotropin-releasing hormone (GnRH) stimulates expression of pituitary adenylate cyclase-activating polypeptide (PACAP) in the pituitary gonadotropes via both the protein kinase A (PKA) and protein kinase c (PKC) signaling systems.
Constance M Grafer, Robin Thomas, Litsa Lambrakos, Ignacio Montoya, Sheryl White, and Lisa M Halvorson
Mol Endocrinol. 2009. [MEDLINE Citation]

Activation of protein kinase C by phorbol 12-myristate 13-acetate suppresses the growth of lung cancer cells through KLF6 induction.
Eiji Tahara, Humam Kadara, Ludovic Lacroix, Dafna Lotan, and Reuben Lotan
Cancer Biol Ther. 2009; 8. [MEDLINE Citation]

Role for Protein Kinase C-alpha in Keratinocyte Growth Arrest.
Anita Jerome-Morais, Heidi R Rahn, Shalini S Tibudan, and Mitchell F Denning
J Invest Dermatol. 2009. [MEDLINE Citation]

Enhancement of calcium transport in Caco-2 monolayer through PKC{zeta}-dependent Cav1.3-mediated transcellular and rectifying paracellular pathways by prolactin.
Narongrit Thongon, La-Iad Nakkrasae, Jirawan Thongbunchoo, Nateetip Krishnamra, and Narattaphol Charoenphandhu
Am J Physiol Cell Physiol. 2009. [MEDLINE Citation]

Selective Sigma Receptor Agonist PRE084 Promotes Neuroprotection and Neurite Elongation Through PKC Signaling on Motoneurons.
Monica-Sofia Guzman-Lenis, Xavier Navarro, and Caty Casas
Neuroscience. 2009. [MEDLINE Citation]

ADAM-10-Mediated N-Cadherin Cleavage Is Protein Kinase C- ${alpha}$ Dependent and Promotes Glioblastoma Cell Migration
Zachary A. Kohutek, Charles G. diPierro, Gerard T. Redpath, and Isa M. Hussaini
J. Neurosci. 2009; 29:4605-4615. [Abstract] [Full Text] [PDF]

Shear Stress Induced Reorganization of the Keratin Intermediate Filament Network Requires Phosphorylation by PKC ${zeta}$
Sivaraj Sivaramakrishnan, Jaime L. Schneider, Albert Sitikov, Robert D. Goldman, and Karen M. Ridge
Mol. Biol. Cell. published 8 April 2009, 10.1091/mbc.E08-10-1028 [Abstract] [PDF]

PKC ${gamma}$ -induced trafficking of AMPA receptors in embryonic zebrafish depends on NSF and PICK1
Shunmoogum A. Patten and Declan W. Ali
PNAS. published 6 April 2009, 10.1073/pnas.0811171106 [Abstract] [PDF]

Inhibition of protein kinase C in diabetic nephropathy—where do we stand?
Jan Menne, Matthias Meier, Joon-Keun Park, and Hermann Haller
Nephrol. Dial. Transplant. published 6 April 2009, 10.1093/ndt/gfp150 [Extract] [Full Text] [PDF]

Crucial implication of protein kinase C (PKC)- ${delta}$ , PKC- ${zeta}$ , ERK-1/2, and p38 MAPK in migration of human asthmatic eosinophils
Anick Langlois, Francois Chouinard, Nicolas Flamand, Claudine Ferland, Marek Rola-Pleszczynski, and Michel Laviolette
J. Leukoc. Biol. 2009; 85:656-663. [Abstract] [Full Text] [PDF]

OAG induces an additional PKC-, PI3K-, and Rac2-mediated signaling pathway up-regulating NOX2 activity, independently of Ca²⁺ entry
Sabrina Bréchard, Alexandre Salsmann, and Eric J. Tschirhart
J. Leukoc. Biol. 2009; 85:638-647. [Abstract] [Full Text] [PDF]

Mice deficient in PKCβ and apolipoprotein E display decreased atherosclerosis
Evis Harja, Jong Sun Chang, Yan Lu, Michael Leitges, Yu Shan Zou, Ann Marie Schmidt, and Shi-Fang Yan
FASEB J. 2009; 23:1081-1091. [Abstract] [Full Text] [PDF]

Investigation of the marine compound spongistatin 1 links the inhibition of PKC ${alpha}$ translocation to nonmitotic effects of tubulin antagonism in angiogenesis
Andrea S. Rothmeier, Ivan Ischenko, Jos Joore, Dorota Garczarczyk, Robert Fürst, Christiane J. Bruns, Angelika M. Vollmar, and Stefan Zahler
FASEB J. 2009; 23:1127-1137. [Abstract] [Full Text] [PDF]

Peroxide generation by p47^phox-Src activation of Nox2 has a key role in protein kinase C-induced arterial smooth muscle contraction
Sachin A. Gupte, Pawel M. Kaminski, Shimran George, Lioubov Kouznestova, Susan C. Olson, Rajamma Mathew, Thomas H. Hintze, and Michael S. Wolin
Am J Physiol Heart Circ Physiol. 2009; 296:H1048-H1057. [Abstract] [Full Text] [PDF]

Gonadotropin-Releasing Hormone and Protein Kinase C Signaling to ERK: Spatiotemporal Regulation of ERK by Docking Domains and Dual-Specificity Phosphatases
Stephen Paul Armstrong, Christopher James Caunt, and Craig Alexander McArdle
Mol. Endocrinol. 2009; 23:510-519. [Abstract] [Full Text] [PDF]

Protein kinase C-dependent ${alpha}$ -secretory processing of the amyloid precursor protein is mediated by phosphorylation of myosin II-B
Francesca Argellati, Cinzia Domenicotti, Mario Passalacqua, Elzbieta Janda, Edon Melloni, Umberto M. Marinari, Maria A. Pronzato, and Roberta Ricciarelli
FASEB J. 2009; 23:1246-1251. [Abstract] [Full Text] [PDF]

Role of protein kinase C and phosphoinositide 3-kinase-Akt in substance P-induced proinflammatory pathways in mouse macrophages
Jia Sun, Raina Devi Ramnath, Ramasamy Tamizhselvi, and Madhav Bhatia
FASEB J. 2009; 23:997-1010. [Abstract] [Full Text] [PDF]

Regulation of the phagocyte NADPH oxidase activity: phosphorylation of gp91^phox/NOX2 by protein kinase C enhances its diaphorase activity and binding to Rac2, p67^phox, and p47^phox
Houssam Raad, Marie-Hélène Paclet, Tarek Boussetta, Yolande Kroviarski, Françoise Morel, Mark T. Quinn, Marie-Anne Gougerot-Pocidalo, Pham My-Chan Dang, and Jamel El-Benna
FASEB J. 2009; 23:1011-1022. [Abstract] [Full Text] [PDF]