Modulation of PKC signaling alters the shear stress-mediated increases in endothelial nitric oxide synthase transcription: role of STAT3
Neetu Sud, Sanjiv Kumar, Stephen Wedgwood, and Stephen M. Black
Am J Physiol Lung Cell Mol Physiol. 2009; 296:L519-L526.  [Abstract] [Full Text] [PDF]

SARS-CoV proteins decrease levels and activity of human ENaC via activation of distinct PKC isoforms
Hong-Long Ji, Weifeng Song, Zhiqian Gao, Xue-Feng Su, Hong-Guang Nie, Yi Jiang, Ji-Bin Peng, Yu-Xian He, Ying Liao, Yong-Jian Zhou, Albert Tousson, and Sadis Matalon
Am J Physiol Lung Cell Mol Physiol. 2009; 296:L372-L383.  [Abstract] [Full Text] [PDF]

Involvement of nuclear PLCβ1 in lamin B1 phosphorylation and G₂/M cell cycle progression
Roberta Fiume, Giulia Ramazzotti, Gabriella Teti, Francesca Chiarini, Irene Faenza, Giovanni Mazzotti, Anna Maria Billi, and Lucio Cocco
FASEB J. 2009; 23:957-966.  [Abstract] [Full Text] [PDF]

Angiotensin II Induces Renal Plasminogen Activator Inhibitor-1 and Cyclooxygenase-2 Expression Posttranscriptionally via Activation of the mRNA-Stabilizing Factor Human-Antigen R
Anke Doller, Stefan Gauer, Ewelina Sobkowiak, Helmut Geiger, Josef Pfeilschifter, and Wolfgang Eberhardt
Am. J. Pathol. published 26 February 2009, 10.2353/ajpath.2009.080652  [Abstract]

Overexpression of Carnitine Palmitoyltransferase-1 in Skeletal Muscle Is Sufficient to Enhance Fatty Acid Oxidation and Improve High-Fat Diet–Induced Insulin Resistance
Clinton R. Bruce, Andrew J. Hoy, Nigel Turner, Matthew J. Watt, Tamara L. Allen, Kevin Carpenter, Gregory J. Cooney, Mark A. Febbraio, and Edward W. Kraegen
Diabetes. 2009; 58:550-558.  [Abstract] [Full Text] [PDF]

Hypoxia-Regulated Activity of PKC in the Lens
Vladimir Akoyev, Satyabrata Das, Snehalata Jena, Laura Grauer, and Dolores J. Takemoto
Invest. Ophthalmol. Vis. Sci. 2009; 50:1271-1282.  [Abstract] [Full Text] [PDF]

Role of Protein Kinase C in the Expression of Endothelin Converting Enzyme-1
Mogher Khamaisi, Rachel Dahan, Saher Hamed, Zaid Abassi, Samuel N. Heyman, and Itamar Raz
Endocrinology. 2009; 150:1440-1449.  [Abstract] [Full Text] [PDF]

Role of NADPH Oxidase in Retinal Microvascular Permeability Increase by RAGE Activation
Christina M. Warboys, Hong-Boon Toh, and Paul A. Fraser
Invest. Ophthalmol. Vis. Sci. 2009; 50:1319-1328.  [Abstract] [Full Text] [PDF]

Exogenous Brain-Derived Neurotrophic Factor (BDNF) Reverts Phenotypic Changes in the Retinas of Transgenic Mice Lacking the bdnf Gene
Blanca Arango-González, Alessandro Cellerino, and Konrad Kohler
Invest. Ophthalmol. Vis. Sci. 2009; 50:1416-1422.  [Abstract] [Full Text] [PDF]

Dextromethorphan reduces oxidative stress and inhibits atherosclerosis and neointima formation in mice
Shu-Lin Liu, Yi-Heng Li, Guey-Yueh Shi, Sei-Hui Tang, Shinn-Jong Jiang, Chia-Wei Huang, Ping-Yen Liu, Jau-Shyong Hong, and Hua-Lin Wu
Cardiovasc Res. published 24 February 2009, 10.1093/cvr/cvp043  [Abstract] [Full Text] [PDF]

miR-205 Exerts Tumor-Suppressive Functions in Human Prostate through Down-regulation of Protein Kinase C
Paolo Gandellini, Marco Folini, Nicole Longoni, Marzia Pennati, Mara Binda, Maurizio Colecchia, Roberto Salvioni, Rosanna Supino, Roberta Moretti, Patrizia Limonta, Riccardo Valdagni, Maria Grazia Daidone, and Nadia Zaffaroni
Cancer Res. published 24 February 2009, 10.1158/0008-5472.CAN-08-2894  [Abstract]

Cytomegaloviral proteins that associate with the nuclear lamina: components of a postulated nuclear egress complex.
J Milbradt, S Auerochs, H Sticht, and M Marschall
J Gen Virol. 2009; 90: 579. [MEDLINE Citation]

TNF induced activation of pulmonary microvessel endothelial cells: a role for GSK3{beta}
Arnold Johnson
Am J Physiol Lung Cell Mol Physiol. 2009. [MEDLINE Citation]

Up-regulation of voltage-gated Na+ channels by long-term activation of the ghrelin-growth hormone secretagogue receptor in clonal GC somatotropes.
Belisario Dominguez, Ricardo Felix, and Eduardo Monjaraz
Am J Physiol Endocrinol Metab. 2009. [MEDLINE Citation]

Regulation of the Ras-GTPase activating protein neurofibromin by C-tail phosphorylation; implications for protein kinase C/Ras/extracellular signal-regulated kinase 1/2 pathway signalling and neuronal differentiation.
George Leondaritis, Loizos Petrikkos, and Dimitra Mangoura
J Neurochem. 2009. [MEDLINE Citation]

Clinical characteristics of paroxysmal kinesigenic choreoathetosis: Diagnosis, treatment and prognosis.
H Kang, Q Hu, X Liu, F Xu, L Chen, and S Zhu
J Huazhong Univ Sci Technolog Med Sci. 2009; 29: 118. [MEDLINE Citation]

Effect of Phorbol Esters on the Macrophage-Mediated Biodegradation of Polyurethanes via Protein Kinase C Activation and Other Pathways.
JE McBane, JP Santerre, and R Labow
J Biomater Sci Polym Ed. 2009; 20: 437. [MEDLINE Citation]

Differential kinase requirement for enhancement of FcgammaR-mediated phagocytosis in alveolar macrophages by leukotriene B(4) vs. D(4).
M R M Campos, C H Serezani, M Peters-Golden, and S Jancar
Mol Immunol. 2009. [MEDLINE Citation]

The role of PKA and PKCepsilon pathways in prostaglandin E-mediated hypernociception.
D Sachs, C F Villarreal, F Q Cunha, C A Parada, and S H Ferreira
Br J Pharmacol. 2009. [MEDLINE Citation]

Protein kinase Cepsilon: an oncogene and emerging tumor biomarker.
Michael A Gorin and Quintin Pan
Mol Cancer. 2009; 8: 9. [MEDLINE Citation]

Meta-analysis of Oncogenic Protein Kinase C{iota} Signaling in Lung Adenocarcinoma.
Eda Erdogan, Eric W Klee, E Aubrey Thompson, and Alan P Fields
Clin Cancer Res. 2009. [MEDLINE Citation]

Protein kinase Cbeta is an effective target for chemoprevention of colon cancer.
AP Fields, SR Calcagno, M Krishna, S Rak, M Leitges, and NR Murray
Cancer Res. 2009; 69: 1643. [MEDLINE Citation]

Role of protein kinase C epsilon (PKCvarepsilon) in the reduction of ethanol reinforcement due to mGluR5 antagonism in the nucleus accumbens shell.
Justin T Gass and M Foster Olive
Psychopharmacology (Berl). 2009. [MEDLINE Citation]

Phase I study of bryostatin 1, a protein kinase C modulator, preceding cisplatin in patients with refractory non-hematologic tumors.
Anna C Pavlick, Jennifer Wu, John Roberts, Mark A Rosenthal, Anne Hamilton, Scott Wadler, Kathleen Farrell, Michelle Carr, David Fry, Anthony J Murgo, Ruth Oratz, Howard Hochster, Leonard Liebes, and Franco Muggia
Cancer Chemother Pharmacol. 2009. [MEDLINE Citation]

Effect of Phorbol Esters on the Macrophage-Mediated Biodegradation of Polyurethanes via Protein Kinase C Activation and Other Pathways.
JE McBane, JP Santerre, and R Labow
J Biomater Sci Polym Ed. 2009; 20: 437. [MEDLINE Citation]

Regulation of the Ras-GTPase activating protein neurofibromin by C-tail phosphorylation; implications for protein kinase C/Ras/extracellular signal-regulated kinase 1/2 pathway signalling and neuronal differentiation.
George Leondaritis, Loizos Petrikkos, and Dimitra Mangoura
J Neurochem. 2009. [MEDLINE Citation]

Long-term extracellular signal-related kinase activation following cadmium intoxication is negatively regulated by a protein kinase C-dependent pathway affecting cadmium transport.
Patrick Martin, Kim E Boulukos, Marie C Poggi, and Philippe Pognonec
FEBS J. 2009. [MEDLINE Citation]

[Effect of ionising irradiation on outward K+ current in rat aorta smooth muscle cells: the role of protein kinase C]
Fiziol Zh. 2008; 54: 30. [MEDLINE Citation]

Glucose-Dependent Enhancement of Diabetic Bladder Contraction Is Associated with a Rho Kinase-Regulated Protein Kinase C Pathway
Koji Nobe, Taigi Yamazaki, Naoki Tsumita, Terumasa Hashimoto, and Kazuo Honda
J. Pharmacol. Exp. Ther. 2009; 328:940-950.  [Abstract] [Full Text] [PDF]

Protein Kinase Cβ Is a Critical Regulator of Dopamine Transporter Trafficking and Regulates the Behavioral Response to Amphetamine in Mice
Rong Chen, Cheryse A. Furman, Minjia Zhang, Myung N. Kim, Robert W. Gereau, IV, Michael Leitges, and Margaret E. Gnegy
J. Pharmacol. Exp. Ther. 2009; 328:912-920.  [Abstract] [Full Text] [PDF]

Rab2 Utilizes Glyceraldehyde-3-phosphate Dehydrogenase and Protein Kinase C to Associate with Microtubules and to Recruit Dynein
Ellen J. Tisdale, Fouad Azizi, and Cristina R. Artalejo
J. Biol. Chem. 2009; 284:5876-5884.  [Abstract] [Full Text] [PDF]

Protein kinase C-theta is required for NK cell activation and in vivo control of tumor progression.
JI Aguilo, J Garaude, J Pardo, M Villalba, and A Anel
J Immunol. 2009; 182: 1972. [MEDLINE Citation]

Protein Kinase C{delta} Differentially Regulates Platelet Functional Responses.
Ramya Chari, Todd Getz, Bela Nagy Jr, Kamala Bhavaraju, Yingying Mao, Yamini Saraswathy Bynagari, Swaminathan Murugappan, Keiko Nakayama, and Satya P Kunapuli
Arterioscler Thromb Vasc Biol. 2009. [MEDLINE Citation]

Activation of protein kinase C eta (PKCeta ) by type I interferons (IFNs).
Amanda J Redig, Antonella Sassano, Beata Majchrzak-Kita, Efstratios Katsoulidis, Hui Liu, Jessica K Altman, Eleanor N Fish, Amittha Wickrema, and Leonidas C Platanias
J Biol Chem. 2009. [MEDLINE Citation]

Critical role of atypical protein kinase C in activating hepatic SREBP-1c and NFkappa B in obesity.
Mini P Sajan, Mary L Standaert, Sonali Nimal, Usha Varanasi, Tina Pastoor, Steven Mastorides, Ursula Braun, Michael Leitges, and Robert Farese
J Lipid Res. 2009. [MEDLINE Citation]

Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling.
AS Baer, YA Syed, SU Kang, D Mitteregger, R Vig, C Ffrench-Constant, RJ Franklin, F Altmann, G Lubec, and MR Kotter
Brain. 2009; 132: 465. [MEDLINE Citation]

Involvement of protein kinase C isoenzymes in Trypanosoma cruzi metacyclogenesis induced by oleic acid.
Maria Laura Belaunzaran, Estela Maria Lammel, Guadalupe Gimenez, Marisa Judith Wainszelbaum, and Elvira Luisa Durante de Isola
Parasitol Res. 2009. [MEDLINE Citation]

Involvement of Protein Kinase C in the Regulation of Na(+)/Ca(2+) Exchanger in Bovine Adrenal Chromaffin Cells.
Shin Soma, Haruhiro Kuwashima, Chiaki Matsumura, and Tomohiko Kimura
Clin Exp Pharmacol Physiol. 2009. [MEDLINE Citation]

Role of protein kinase C and mu-opioid receptor (MOPr) desensitization in tolerance to morphine in rat locus coeruleus neurons.
CP Bailey, J Llorente, BH Gabra, FL Smith, WL Dewey, E Kelly, and G Henderson
Eur J Neurosci. 2009; 29: 307. [MEDLINE Citation]

Temperature and protein kinase C modulation of gonadotropin-releasing hormone receptors in pituitary cells from intact or castrated male rats.
P Leblanc, F Haour, A I'heritier, F Mounier, and C Kordon
J Neuroendocrinol. 1990; 2: 509. [MEDLINE Citation]

Modulation of Neuropeptide-lnduced Membrane Currents by Protein Kinase C in Xenopus Oocytes Injected with GH Pituitary Cell Poly(A) RNA.
S Mahlmann, JR Schwarz, and W Meyerhof
J Neuroendocrinol. 1989; 1: 65. [MEDLINE Citation]

PKC-{beta}1 Mediates Glucose-Induced Akt Activation and TGF-{beta}1 Upregulation in Mesangial Cells.
Dongcheng Wu, Fangfang Peng, Baifang Zhang, Alistair J Ingram, Darren J Kelly, Richard E Gilbert, Bo Gao, and Joan C Krepinsky
J Am Soc Nephrol. 2009. [MEDLINE Citation]

Pivotal Advance: PKC{zeta} is required for migration of macrophages.
Hua Guo, Yongjie Ma, Baogang Zhang, Baocun Sun, Ruifang Niu, Guoguang Ying, and Ning Zhang
J Leukoc Biol. 2009. [MEDLINE Citation]

The signal transduction pathway of PKC/NF-kappa B/c-fos may be involved in the influence of high glucose on the cardiomyocytes of neonatal rats.
Wang Min, Zhang Wen Bin, Zhou Bin Quan, Zhu Jun Hui, and Fu Guo Sheng
Cardiovasc Diabetol. 2009; 8: 8. [MEDLINE Citation]

Safingol (L-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway.
J Coward, G Ambrosini, E Musi, JP Truman, A Haimovitz-Friedman, JC Allegood, E Wang, AH Merrill Jr, and GK Schwartz
Autophagy. 2009; 5: 184. [MEDLINE Citation]

Adenosine A2A receptors enhance GABA transport into nerve terminals by restraining PKC inhibition of GAT-1.
Sofia Cristovao-Ferreira, Sandra H Vaz, Joaquim A Ribeiro, and Ana M Sebastiao
J Neurochem. 2009. [MEDLINE Citation]

Protein kinase C-theta is required for NK cell activation and in vivo control of tumor progression.
JI Aguilo, J Garaude, J Pardo, M Villalba, and A Anel
J Immunol. 2009; 182: 1972. [MEDLINE Citation]

Arachidonic acid release by H(2)O(2) mediated proliferation of mouse embryonic stem cells: Involvement of Ca(2+)/PKC and MAPKs-induced EGFR transactivation.
Sang Hun Lee, Sun Im Na, Jung Sun Heo, Min Hee Kim, Yun Hee Kim, Min Young Lee, Seong Hong Kim, Yun Jung Lee, and Ho Jae Han
J Cell Biochem. 2009. [MEDLINE Citation]

Protein Kinase C{delta} Differentially Regulates Platelet Functional Responses.
Ramya Chari, Todd Getz, Bela Nagy Jr, Kamala Bhavaraju, Yingying Mao, Yamini Saraswathy Bynagari, Swaminathan Murugappan, Keiko Nakayama, and Satya P Kunapuli
Arterioscler Thromb Vasc Biol. 2009. [MEDLINE Citation]

Activation of protein kinase C eta (PKCeta ) by type I interferons (IFNs).
Amanda J Redig, Antonella Sassano, Beata Majchrzak-Kita, Efstratios Katsoulidis, Hui Liu, Jessica K Altman, Eleanor N Fish, Amittha Wickrema, and Leonidas C Platanias
J Biol Chem. 2009. [MEDLINE Citation]

Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling.
AS Baer, YA Syed, SU Kang, D Mitteregger, R Vig, C Ffrench-Constant, RJ Franklin, F Altmann, G Lubec, and MR Kotter
Brain. 2009; 132: 465. [MEDLINE Citation]

Insulin Receptor Substrate-2 Mediated Insulin-like Growth Factor-I Receptor Overexpression in Pancreatic Adenocarcinoma through Protein Kinase C
Junhye Kwon, Susann Stephan, Ananya Mukhopadhyay, Michael H. Muders, Shamit K. Dutta, Julie S. Lau, and Debabrata Mukhopadhyay
Cancer Res. 2009; 69:1350-1357.  [Abstract] [Full Text] [PDF]

Wnt5a Is Required for Endothelial Differentiation of Embryonic Stem Cells and Vascularization via Pathways Involving Both Wnt/β-Catenin and Protein Kinase C
Dong-Hwa Yang, Ju-Young Yoon, Soung-Hoon Lee, Vitezslav Bryja, Emma R. Andersson, Ernest Arenas, Young-Guen Kwon, and Kang-Yell Choi
Circ. Res. 2007; 104:372-379.  [Abstract] [Full Text] [PDF]

Protein Kinase Cβ Is an Effective Target for Chemoprevention of Colon Cancer
Alan P. Fields, Shelly R. Calcagno, Murli Krishna, Sofija Rak, Michael Leitges, and Nicole R. Murray
Cancer Res. 2009; 69:1643-1650.  [Abstract] [Full Text] [PDF]

Protein Kinase C Differentially Regulates Platelet Functional Responses
Ramya Chari, Todd Getz, Bela Nagy, Jr, Kamala Bhavaraju, Yingying Mao, Yamini Saraswathy Bynagari, Swaminathan Murugappan, Keiko Nakayama, and Satya P. Kunapuli
Arterioscler. Thromb. Vasc. Biol. published 12 February 2009, 10.1161/ATVBAHA.109.184010  [Abstract] [PDF]

Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling
Marc S. Raab, Iris Breitkreutz, Giovanni Tonon, Jing Zhang, Patrick J. Hayden, Thu Nguyen, Johannes H. Fruehauf, Boris K. Lin, Dharminder Chauhan, Teru Hideshima, Nikhil C. Munshi, Kenneth C. Anderson, and Klaus Podar
Blood. 2009; 113:1513-1521.  [Abstract] [Full Text] [PDF]

Wnt5a Is Required for Endothelial Differentiation of Embryonic Stem Cells and Vascularization via Pathways Involving Both Wnt/β-Catenin and Protein Kinase C
Dong-Hwa Yang, Ju-Young Yoon, Soung-Hoon Lee, Vitezslav Bryja, Emma R. Andersson, Ernest Arenas, Young-Guen Kwon, and Kang-Yell Choi
Circ. Res. 2007; 104:372-379.  [Abstract] [Full Text] [PDF]

Protein kinase C activation stabilizes LDL receptor mRNA via the JNK pathway in HepG2 cells
Noelle B. Vargas, Brandy Y. Brewer, Terry B. Rogers, and Gerald M. Wilson
J. Lipid Res. 2009; 50:386-397.  [Abstract] [Full Text] [PDF]

PKC-1 Mediates Glucose-Induced Akt Activation and TGF-1 Upregulation in Mesangial Cells
Dongcheng Wu, Fangfang Peng, Baifang Zhang, Alistair J. Ingram, Darren J. Kelly, Richard E. Gilbert, Bo Gao, and Joan C. Krepinsky
J. Am. Soc. Nephrol. published 11 February 2009, 10.1681/ASN.2008040445  [Abstract]

Activation of protein kinase C eta (PKC) by type I interferons (IFNs)
Amanda J. Redig, Antonella Sassano, Beata Majchrzak-Kita, Efstratios Katsoulidis, Hui Liu, Jessica K. Altman, Eleanor N. Fish, Amittha Wickrema, and Leonidas C. Platanias
J. Biol. Chem. published 11 February 2009, 10.1074/jbc.M807254200  [Abstract] [PDF]

Inhibition of PKC-β by Ruboxistaurin Preserves Cardiac Function and Reduces Extra-Cellular Matrix Production in Diabetic Cardiomyopathy
Kim A. Connelly, Darren J. Kelly, Yuan Zhang, David L. Prior, Andrew Advani, Alison J. Cox, Kerri Thai, Henry Krum, and Richard E. Gilbert
Circ Heart Fail. published 10 February 2009, 10.1161/CIRCHEARTFAILURE.108.765750  [Abstract]

Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling
Alexandra S. Baer, Yasir A. Syed, Sung Ung Kang, Dieter Mitteregger, Raluca Vig, Charles ffrench-Constant, Robin J. M. Franklin, Friedrich Altmann, Gert Lubec, and Mark R. Kotter
Brain. 2009; 132:465-481.  [Abstract] [Full Text] [PDF]

Protein kinase C epsilon in cell division: Control of abscission.
Adrian T Saurin, Nicola Brownlow, and Peter J Parker
Cell Cycle. 2009; 8. [MEDLINE Citation]

Reduction of Protein kinase C zeta inhibits migration and invasion of human glioblastoma cells.
Hua Guo, Feng Gu, Wenliang Li, Baogang Zhang, Ruifang Niu, Li Fu, Ning Zhang, and Yongjie Ma
J Neurochem. 2009. [MEDLINE Citation]

Role of protein kinase C in 15-HETE-induced hypoxic pulmonary vasoconstriction.
Lei Guo, Xiaobo Tang, Xiaojie Chu, Lihua Sun, Lei Zhang, Zhaoping Qiu, Shuo Chen, Yumei Li, Xiaodong Zheng, and Daling Zhu
Prostaglandins Leukot Essent Fatty Acids. 2009. [MEDLINE Citation]

Involvement of protein kinase C signalling and mitogen-activated protein kinase in the amebocyte-producing organ of Biomphalaria glabrata (Mollusca).
Zahra Salamat and John T Sullivan
Dev Comp Immunol. 2009. [MEDLINE Citation]

Homocysteine decreases platelet NO level via protein kinase C activation.
MG Signorello, A Segantin, M Passalacqua, and G Leoncini
Nitric Oxide. 2009; 20: 104. [MEDLINE Citation]

Insulin Receptor Substrate-2 Mediated Insulin-like Growth Factor-I Receptor Overexpression in Pancreatic Adenocarcinoma through Protein Kinase C{delta}
Junhye Kwon, Susann Stephan, Ananya Mukhopadhyay, Michael H Muders, Shamit K Dutta, Julie S Lau, and Debabrata Mukhopadhyay
Cancer Res. 2009. [MEDLINE Citation]

Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis.
Lurong Lian, Yanfeng Wang, Matthew Flick, John Choi, Edward W Scott, Jay Degen, Mark A Lemmon, and Charles S Abrams
Blood. 2009. [MEDLINE Citation]

Angiotensin II inhibits the Na+-K+ pump via PKC dependent activation of NADPH oxidase.
Caroline N White, Gemma A Figtree, Chia-Chi Liu, Alvaro Garcia, Elisha J Hamilton, Karin Km Chia, and Helge H Rasmussen
Am J Physiol Cell Physiol. 2009. [MEDLINE Citation]

PKC inhibitors: potential in T cell-dependent immune diseases.
Gottfried Baier and Jurgen Wagner
Curr Opin Cell Biol. 2009. [MEDLINE Citation]

5'-N-ethylcarboxamide induces IL-6 expression via MAPKs and NF-kappaB activation through Akt, Ca(2+)/PKC, cAMP signaling pathways in mouse embryonic stem cells.
Mi Ok Kim, Min Hee Kim, Sang Hun Lee, Han Na Suh, Yu Jin Lee, Min Yong Lee, and Ho Jae Han
J Cell Physiol. 2009. [MEDLINE Citation]

Protein Kinase C- Is Required for NK Cell Activation and In Vivo Control of Tumor Progression
Juan I. Aguiló, Johan Garaude, Julián Pardo, Martín Villalba, and Alberto Anel
J. Immunol. 2009; 182:1972-1981.  [Abstract] [Full Text] [PDF]

Protein Kinase C- and Phosphatidylinositol 3-Kinase/Akt Activate Mammalian Target of Rapamycin to Modulate NF-B Activation and Intercellular Adhesion Molecule-1 (ICAM-1) Expression in Endothelial Cells
Mohd Minhajuddin, Kaiser M. Bijli, Fabeha Fazal, Antonella Sassano, Keiichi I. Nakayama, Nissim Hay, Leonidas C. Platanias, and Arshad Rahman
J. Biol. Chem. 2009; 284:4052-4061.  [Abstract] [Full Text] [PDF]

Overexpression of phospholipase D enhances matrix metalloproteinase-2 expression and glioma cell invasion via protein kinase C and protein kinase A/NF-B/Sp1-mediated signaling pathways
Mi Hee Park, Bong-Hyun Ahn, Yong-Kil Hong, and Do Sik Min
Carcinogenesis. 2009; 30:356-365.  [Abstract] [Full Text] [PDF]

Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis
Lurong Lian, Yanfeng Wang, Matthew Flick, John Choi, Edward W. Scott, Jay Degen, Mark A. Lemmon, and Charles S. Abrams
Blood. published 3 February 2009, 10.1182/blood-2008-09-178913  [Abstract] [PDF]

Protein kinase C in heart failure: a therapeutic target?
Suresh Selvaraj Palaniyandi, Lihan Sun, Julio Cesar Batista Ferreira, and Daria Mochly-Rosen
Cardiovasc Res. 2009. [MEDLINE Citation]

Gonadotropin releasing hormone and protein kinase C signaling to ERK: Spatiotemporal regulation of ERK by docking domains and dual-specificity phosphatases.
Stephen Paul Armstrong, Christopher James Caunt, and Craig Alexander McArdle
Mol Endocrinol. 2009. [MEDLINE Citation]

Functional suppression of E-cadherin by protein kinase C{delta}
Chien-Lin Chen and Hong-Chen Chen
J Cell Sci. 2009. [MEDLINE Citation]

Phosphorylation of activation transcription factor-2 (ATF-2) at serine 121 by protein kinase C controls c-Jun-mediated activation of transcription.
Takahito Yamasaki, Akinori Takahashi, Jianzhi Pan, Naoto Yamaguchi, and Kazunari K Yokoyama
J Biol Chem. 2009. [MEDLINE Citation]

Peroxide Generation by p47phox-Src Activation of Nox2 Has a Key Role in Protein Kinase C-Induced Arterial Smooth Muscle Contraction.
Sachin A Gupte, Pawel M Kaminski, Shimran George, Lioubov Kouznestova, Susan C Olson, Rajamma Matthew, Thomas H Hintze, and Michael S Wolin
Am J Physiol Heart Circ Physiol. 2009. [MEDLINE Citation]

Rapid estrogen receptor-alpha activation improves ischemic tolerance in aged female rats through a novel protein kinase C epsilon-dependent mechanism.
JL Novotny, AM Simpson, NJ Tomicek, TS Lancaster, and DH Korzick
Endocrinology. 2009; 150: 889. [MEDLINE Citation]

Protein kinase C-Fyn kinase cascade mediates the oleic acid-induced disassembly of neonatal rat cardiomyocyte adherens junctions.
Kwan-Lih Hsu, Han-Jou Fan, Yung-Chia Chen, Yuahn-Sieh Huang, Chia-Huei Chen, Jiahn-Chun Wu, and Seu-Mei Wang
Int J Biochem Cell Biol. 2009. [MEDLINE Citation]

Signal transduction of constitutively active protein kinase C epsilon.
Dorota Garczarczyk, Ewa Toton, Verena Biedermann, Erika Rosivatz, Florian Rechfeld, Maria Rybczynska, and Johann Hofmann
Cell Signal. 2009. [MEDLINE Citation]

Epidermal growth factor-dependent cyclooxygenase-2 induction in gliomas requires protein kinase C-delta.
K Xu, C-M Chang, H Gao, and H-K G Shu
Oncogene. 2009. [MEDLINE Citation]

Synergistic effect of Sorafenib and Sunitinib with Enzastaurin, a selective protein kinase C inhibitor in renal cell carcinoma cell lines.
Ursula Maria Vogl, Walter Berger, Michael Micksche, Christine Pirker, Wolfgang Lamm, Oskar Pichelmeyer, Christoph C Zielinski, and Manuela Schmidinger
Cancer Lett. 2009. [MEDLINE Citation]

PKC{beta} is essential for the development of CLL in the TCL1 transgenic mouse model: Validation of PKC{beta} as a therapeutic target in CLL.
Claudia Holler, Josefina D Pinon, Ursula Denk, Christoph Heyder, Sebastian Hofbauer, Richard Greil, and Alexander Egle
Blood. 2009. [MEDLINE Citation]

EGFR Signals to mTOR Through PKC and Independently of Akt in Glioma.
QW Fan, C Cheng, ZA Knight, D Haas-Kogan, D Stokoe, CD James, F McCormick, KM Shokat, and WA Weiss
Sci Signal. 2009; 2: ra4. [MEDLINE Citation]

Peroxide Generation by p47phox-Src Activation of Nox2 Has a Key Role in Protein Kinase C-Induced Arterial Smooth Muscle Contraction.
Sachin A Gupte, Pawel M Kaminski, Shimran George, Lioubov Kouznestova, Susan C Olson, Rajamma Matthew, Thomas H Hintze, and Michael S Wolin
Am J Physiol Heart Circ Physiol. 2009. [MEDLINE Citation]

Functional suppression of E-cadherin by protein kinase C{delta}
Chien-Lin Chen and Hong-Chen Chen
J Cell Sci. 2009. [MEDLINE Citation]

2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: design and synthesis of a potent and isoform selective PKC-zeta inhibitor.
JI Trujillo, JR Kiefer, W Huang, A Thorarensen, L Xing, NL Caspers, JE Day, KJ Mathis, KK Kretzmer, BA Reitz, RA Weinberg, RA Stegeman, A Wrightstone, L Christine, R Compton, and X Li
Bioorg Med Chem Lett. 2009; 19: 908. [MEDLINE Citation]

IL-1 beta induces urokinase-plasminogen activator expression and cell migration through PKC alpha, JNK1/2, and NF-kappaB in A549 cells.
CY Cheng, HL Hsieh, CC Sun, CC Lin, SF Luo, and CM Yang
J Cell Physiol. 2009; 219: 183. [MEDLINE Citation]

Gonadotropin releasing hormone and protein kinase C signaling to ERK: Spatiotemporal regulation of ERK by docking domains and dual-specificity phosphatases.
Stephen Paul Armstrong, Christopher James Caunt, and Craig Alexander McArdle
Mol Endocrinol. 2009. [MEDLINE Citation]

Phosphorylation of activation transcription factor-2 (ATF-2) at serine 121 by protein kinase C controls c-Jun-mediated activation of transcription.
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