Functional suppression of E-cadherin by protein kinase C
Chien-Lin Chen and Hong-Chen Chen
J. Cell Sci. published 27 January 2009, 10.1242/jcs.035469  [Abstract] [PDF]

Role of cPKC and nPKC in EGF-Stimulated Goblet Cell Proliferation
Marie A. Shatos, Robin R. Hodges, Yoshia Oshi, Jeffrey A. Bair, Driss Zoukhri, Claire Kublin, Kameran Lashkari, and Darlene A. Dartt
Invest. Ophthalmol. Vis. Sci. 2009; 50:614-620.  [Abstract] [Full Text] [PDF]

PKC is essential for the development of CLL in the TCL1 transgenic mouse model: Validation of PKC as a therapeutic target in CLL
Claudia Holler, Josefina D Pinon, Ursula Denk, Christoph Heyder, Sebastian Hofbauer, Richard Greil, and Alexander Egle
Blood. published 23 January 2009, 10.1182/blood-2008-06-160713  [Abstract] [PDF]

Peroxide Generation by p47^phox-Src Activation of Nox2 Has a Key Role in Protein Kinase C-Induced Arterial Smooth Muscle Contraction
Sachin A Gupte, Pawel M Kaminski, Shimran George, Lioubov Kouznestova, Susan C Olson, Rajamma Matthew, Thomas H Hintze, and Michael S. Wolin
Am J Physiol Heart Circ Physiol. published 23 January 2009, 10.1152/ajpheart.00491.2008  [Abstract] [PDF]

Protein kinase C in heart failure: a therapeutic target?
Suresh Selvaraj Palaniyandi, Lihan Sun, Julio Cesar Batista Ferreira, and Daria Mochly-Rosen
Cardiovasc Res. published 24 January 2009, 10.1093/cvr/cvp001  [Abstract] [PDF]

Impaired activation of platelets lacking protein kinase C isoform
Bela Nagy, Jr., Kamala Bhavaraju, Todd Getz, Yamini S. Bynagari, Soochong Kim, and Satya P. Kunapuli
Blood. published 22 January 2009, 10.1182/blood-2008-07-169268  [Abstract] [PDF]

Role of Protein Kinase C and Calcium Entry in KCl-Induced Vascular Smooth Muscle Calcium Sensitization and Feedback Control of Cellular Calcium Levels
Paul H. Ratz and Amy S. Miner
J. Pharmacol. Exp. Ther. 2009; 328:399-408.  [Abstract] [Full Text] [PDF]

Crucial implication of protein kinase C (PKC)-, PKC-, ERK-1/2, and p38 MAPK in migration of human asthmatic eosinophils
Anick Langlois, Francois Chouinard, Nicolas Flamand, Claudine Ferland, Marek Rola-Pleszczynski, and Michel Laviolette
J. Leukoc. Biol. published 21 January 2009, 10.1189/jlb.0808492  [Abstract]

Phosphorylation of Fli1 at threonine 312 by protein kinase C- promotes its interaction with p300/CREB-binding protein-associated factor and subsequent acetylation in response to transforming growth factor-
Yoshihide Asano and Maria Trojanowska
Mol. Cell. Biol. published 21 January 2009, 10.1128/MCB.01320-08  [Abstract] [PDF]

Protein kinase C-β inhibition attenuates the progression of nephropathy in non-diabetic kidney disease
Darren J. Kelly, Amanda J. Edgley, Yuan Zhang, Kerri Thai, Sih Min Tan, Alison J. Cox, Andrew Advani, Kim A. Connelly, Catharine I. Whiteside, and Richard E. Gilbert
Nephrol. Dial. Transplant. published 20 January 2009, 10.1093/ndt/gfn729  [Abstract] [Full Text] [PDF]

Protein kinase C betaII and PKCiota/lambda: collaborating partners in colon cancer promotion and progression.
NR Murray, J Weems, U Braun, M Leitges, and AP Fields
Cancer Res. 2009; 69: 656. [MEDLINE Citation]

Protein kinase C-dependent {alpha}-secretory processing of the amyloid precursor protein is mediated by phosphorylation of myosin II-B.
Francesca Argellati, Cinzia Domenicotti, Mario Passalacqua, Elzbieta Janda, Edon Melloni, Umberto M Marinari, Maria A Pronzato, and Roberta Ricciarelli
FASEB J. 2008. [MEDLINE Citation]

Protein kinase C{beta} is a critical regulator of dopamine transporter trafficking and regulates the behavioral response to amphetamine in mice.
Rong Chen, Cheryse A Furman, Minjia Zhang, Myung N Kim, Robert W Gereau, Michael Leitges, and Margaret E Gnegy
J Pharmacol Exp Ther. 2008. [MEDLINE Citation]

A Protein Kinase C{delta}-Dependent Protein Kinase D Pathway Modulates ERK1/2 and JNK1/2 Phosphorylation and Bim-Associated Apoptosis by Asbestos.
Sylke A Buder-Hoffmann, Arti Shukla, Trisha F Barrett, Maximilian B Macpherson, Karen M Lounsbury, and Brooke T Mossman
Am J Pathol. 2008. [MEDLINE Citation]

Role of protein kinase Calpha in regulation of [Ca2+](I) and force in human myometrium.
VP Fomin, A Kronbergs, S Gunst, D Tang, V Simirskii, M Hoffman, and RL Duncan
Reprod Sci. 2009; 16: 71. [MEDLINE Citation]

Ethanol for cardiac ischemia: the role of protein kinase c.
EN Churchill, MH Disatnik, GR Budas, and D Mochly-Rosen
Ther Adv Cardiovasc Dis. 2008; 2: 469. [MEDLINE Citation]

Phosphoinositide 3-kinase Akt signaling pathway interacts with protein kinase C{beta}2 in the regulation of physiologic developmental hypertrophy and heart function.
Debra L Rigor, Natalya Bodyak, Soochan Bae, Jun H Choi, Li Zhang, Dmitry Ter-Ovanesyan, Zhiheng He, Julie R McMullen, Tetsuo Shioi, Seigo Izumo, George L King, and Peter M Kang
Am J Physiol Heart Circ Physiol. 2009. [MEDLINE Citation]

The chaperones Hsp90 and Cdc37 mediate the maturation and stabilization of protein kinase C through a conserved PXXP motif in the C-terminal tail.
Christine M Gould, Natarajan Kannan, Susan S Taylor, and Alexandra C Newton
J Biol Chem. 2008. [MEDLINE Citation]

Regulation of Human Organic Anion Transporter 1 by Angiotensin II: Involvement of Protein Kinase C{alpha}
Shanshan Li, Peng Duan, and Guofeng You
Am J Physiol Endocrinol Metab. 2008. [MEDLINE Citation]

Epac and Phospholipase C{epsilon} Regulate Ca2+ Release in the Heart by Activation of Protein Kinase C{epsilon} and Calcium-Calmodulin Kinase II.
EA Oestreich, S Malik, SA Goonasekera, BC Blaxall, GG Kelley, RT Dirksen, and AV Smrcka
J Biol Chem. 2009; 284: 1514. [MEDLINE Citation]

PKC eta regulates occludin phosphorylation and epithelial tight junction integrity.
T Suzuki, BC Elias, A Seth, L Shen, JR Turner, F Giorgianni, D Desiderio, R Guntaka, and R Rao
Proc Natl Acad Sci U S A. 2009; 106: 61. [MEDLINE Citation]

Two PKC consensus sites on human Acid- Sensing Ion Channel 1b (hASIC1b) differentially regulate its function.
Edlira Bashari, Yawar Qadri, Zhen-Hong Zhou, Niren Kapoor, Susan Anderson, Robert Meltzer, Catherine M Fuller, and Dale J Benos
Am J Physiol Cell Physiol. 2008. [MEDLINE Citation]

A role for Syndecan-4 in neural induction involving ERK- and PKC-dependent pathways.
Sei Kuriyama and Roberto Mayor
Development. 2009. [MEDLINE Citation]

OAG induces an additional PKC-, PI-3K-, and Rac2-mediated signaling pathway up-regulating NOX2 activity, independently of Ca2+ entry.
Sabrina Brechard, Alexandre Salsmann, and Eric J Tschirhart
J Leukoc Biol. 2008. [MEDLINE Citation]

Sphingosine kinase as an oncogene: autocrine sphingosine 1-phoshate modulates ML-1 thyroid carcinoma cell migration by a mechanism dependent on PKC-{alpha} and ERK1/2.
N Bergelin, T Blom, J Heikkila, C Lof, C Alam, S Balthasar, J P Slotte, A Hinkkanen, and K Tornquist
Endocrinology. 2008. [MEDLINE Citation]

MODULATION OF PKC{sigma} SIGNALING ALTERS THE SHEAR STRESS MEDIATED INCREASES IN ENDOTHELIAL NITRIC OXIDE SYNTHASE TRANSCRIPTION: ROLE OF STAT3.
Neetu Sud, Sanjiv Kumar, Stephen Wedgwood, and Stephen M Black
Am J Physiol Lung Cell Mol Physiol. 2008. [MEDLINE Citation]

SARS-CoV Proteins Decrease Levels and Activity of Human ENaC via Activation of Distinct PKC Isoforms.
Hong-Long Ji, Weifeng Song, Zhiqian Gao, Xue-Feng Su, Hong-Guang Nie, Yi Jiang, Ji-Bin Peng, Yu-Xian He, Ying Liao, Yong-Jian Zhou, Albert Tousson, and Sadis Matalon
Am J Physiol Lung Cell Mol Physiol. 2008. [MEDLINE Citation]

Loss of PKC{lambda}/{iota} impairs Th2 establishment and allergic airway inflammation in vivo.
Jun-Qi Yang, Michael Leitges, Angeles Duran, Maria T Diaz-Meco, and Jorge Moscat
Proc Natl Acad Sci U S A. 2009. [MEDLINE Citation]

Activation of dual oxidases (duox1 and duox2): Differential regulation mediated by PKA and PKC-dependent phosphorylation.
Sabrina Rigutto, Candice Hoste, Helmut Grasberger, Milutin Milenkovic, David Communi, Jacques E Dumont, Bernard Corvilain, Francoise Miot, and Xavier De Deken
J Biol Chem. 2009. [MEDLINE Citation]

Detecting PKC phosphorylation as part of the Wnt/calcium pathway in cutaneous melanoma.
SK Dissanayake and AT Weeraratna
Methods Mol Biol. 2008; 468: 157. [MEDLINE Citation]

Protein Kinase C Negatively Regulates Hedgehog Signaling by Inhibition of Gli1 Activity
Qingsong Cai, Jing Li, Tianyan Gao, Jingwu Xie, and B. Mark Evers
J. Biol. Chem. 2009; 284:2150-2158.  [Abstract] [Full Text] [PDF]

Protein Kinase C (PKC)-dependent Phosphorylation of PDK1 at Ser⁵⁰⁴ and Ser⁵³² Contributes to Palmitate-induced Insulin Resistance
Changhua Wang, Meilian Liu, Ramon A. Riojas, Xiaoban Xin, Zhanguo Gao, Rong Zeng, Jiarui Wu, Lily Q. Dong, and Feng Liu
J. Biol. Chem. 2009; 284:2038-2044.  [Abstract] [Full Text] [PDF]

A role for Syndecan-4 in neural induction involving ERK- and PKC-dependent pathways
Sei Kuriyama and Roberto Mayor
Development. published 14 January 2009, 10.1242/dev.027334  [Abstract] [PDF]

Loss of PKC/ impairs Th2 establishment and allergic airway inflammation in vivo
Jun-Qi Yang, Michael Leitges, Angeles Duran, Maria T. Diaz-Meco, and Jorge Moscat
PNAS. published 14 January 2009, 10.1073/pnas.0805907106  [Abstract] [PDF]

Protein Kinase C βII and PKC/: Collaborating Partners in Colon Cancer Promotion and Progression
Nicole R. Murray, Justin Weems, Ursula Braun, Michael Leitges, and Alan P. Fields
Cancer Res. 2009; 69:656-662.  [Abstract] [Full Text] [PDF]

Activation of dual oxidases (duox1 and duox2): Differential regulation mediated by PKA and PKC-dependent phosphorylation
Sabrina Rigutto, Candice Hoste, Helmut Grasberger, Milutin Milenkovic, David Communi, Jacques E. Dumont, Bernard Corvilain, Françoise Miot, and Xavier De Deken
J. Biol. Chem. published 14 January 2009, 10.1074/jbc.M806893200  [Abstract] [PDF]

Modulation of Transient and Persistent Inward Currents by Activation of Protein Kinase C in Spinal Ventral Neurons of the Neonatal Rat
Yue Dai, Larry M. Jordan, and Brent Fedirchuk
J Neurophysiol. 2009; 101:112-128.  [Abstract] [Full Text] [PDF]

Epac and Phospholipase C Regulate Ca²⁺ Release in the Heart by Activation of Protein Kinase C and Calcium-Calmodulin Kinase II
Emily A. Oestreich, Sundeep Malik, Sanjeewa A. Goonasekera, Burns C. Blaxall, Grant G. Kelley, Robert T. Dirksen, and Alan V. Smrcka
J. Biol. Chem. 2009; 284:1514-1522.  [Abstract] [Full Text] [PDF]

Overexpression of Phospholipase D Enhances Matrix Metalloproteinase-2 Expression and Glioma Cell Invasion via Protein Kinase C and Protein Kinase A/NFB/Sp1-mediated Signaling Pathways
Mi Hee Park, Bong-Hyun Ahn, Yong-Kil Hong, and Do Sik Min
Carcinogenesis. published 6 January 2009, 10.1093/carcin/bgn287  [Abstract] [PDF]

PKC regulates occludin phosphorylation and epithelial tight junction integrity
Takuya Suzuki, Bertha C. Elias, Ankur Seth, Le Shen, Jerrold R. Turner, Francesco Giorgianni, Dominic Desiderio, Ramareddy Guntaka, and Radhakrishna Rao
PNAS. 2009; 106:61-66.  [Abstract] [Full Text] [PDF]

Phosphoinositide 3-kinase Akt signaling pathway interacts with protein kinase C2 in the regulation of physiologic developmental hypertrophy and heart function
Debra L. Rigor, Natalya Bodyak, Soochan Bae, Jun H. Choi, Li Zhang, Dmitry Ter-Ovanesyan, Zhiheng He, Julie R. McMullen, Tetsuo Shioi, Seigo Izumo, George L. King, and Peter M. Kang
Am J Physiol Heart Circ Physiol. published 2 January 2009, 10.1152/ajpheart.00562.2008  [Abstract] [PDF]

Protein Kinase C Contributes to the Maintenance of Contractile Force in Human Ventricular Cardiomyocytes
Andrea Molnár, Attila Borbély, Dániel Czuriga, Siket M. Ivetta, Szabolcs Szilágyi, Zita Hertelendi, Eniko T. Pásztor, Ágnes Balogh, Zoltán Galajda, Tamás Szerafin, Kornelia Jaquet, Zoltán Papp, István Édes, and Attila Tóth
J. Biol. Chem. 2009; 284:1031-1039.  [Abstract] [Full Text] [PDF]

Characterization of the Differential Roles of the Twin C1a and C1b Domains of Protein Kinase C
Yongmei Pu, Susan H. Garfield, Noemi Kedei, and Peter M. Blumberg
J. Biol. Chem. 2009; 284:1302-1312.  [Abstract] [Full Text] [PDF]

A Feed-Forward Loop Involving Protein Kinase C and MicroRNAs Regulates Tumor Cell Cycle
Ezra E.W. Cohen, Hongyan Zhu, Mark W. Lingen, Leslie E. Martin, Wen-Liang Kuo, Eugene A. Choi, Masha Kocherginsky, Joel S. Parker, Christine H. Chung, and Marsha Rich Rosner
Cancer Res. 2009; 69:65-74.  [Abstract] [Full Text] [PDF]

PCPH/ENTPD5 Expression Confers to Prostate Cancer Cells Resistance against Cisplatin-Induced Apoptosis through Protein Kinase C–Mediated Bcl-2 Stabilization
Joaquín Villar, Humair S. Quadri, Insun Song, York Tomita, Oscar M. Tirado, and Vicente Notario
Cancer Res. 2009; 69:102-110.  [Abstract] [Full Text] [PDF]

Fibroblast growth factor receptor2 promotes osteogenic differentiation in mesenchymal cells via extracellular-related kinase and protein kinase c signalling
Hichem Miraoui, Karim Oudina, Hervé Petite, Yukiho Tanimoto, Keiji Moriyama, and Pierre J. Marie
J. Biol. Chem. published 30 December 2008, 10.1074/jbc.M805432200  [Abstract] [PDF]

High glucose-induced Nox1-derived superoxides downregulate PKC-βII, which subsequently decreases ACE2 expression and ANG(1-7) formation in rat VSMCs
Eduard N. Lavrentyev and Kafait U. Malik
Am J Physiol Heart Circ Physiol. 2009; 296:H106-H118.  [Abstract] [Full Text] [PDF]

OAG induces an additional PKC-, PI-3K-, and Rac2-mediated signaling pathway up-regulating NOX2 activity, independently of Ca²⁺ entry
Sabrina Bréchard, Alexandre Salsmann, and Eric J. Tschirhart
J. Leukoc. Biol. published 31 December 2008, 10.1189/jlb.0508330  [Abstract]

MODULATION OF PKC SIGNALING ALTERS THE SHEAR STRESS MEDIATED INCREASES IN ENDOTHELIAL NITRIC OXIDE SYNTHASE TRANSCRIPTION: ROLE OF STAT3
Neetu Sud, Sanjiv Kumar, Stephen Wedgwood, and Stephen M Black
Am J Physiol Lung Cell Mol Physiol. published 31 December 2008, 10.1152/ajplung.90534.2008  [Abstract] [PDF]

Sphingosine kinase as an oncogene: autocrine sphingosine 1-phoshate modulates ML-1 thyroid carcinoma cell migration by a mechanism dependent on PKC- and ERK1/2
N Bergelin, T Blom, J Heikkilä, C Löf, C Alam, S Balthasar, J P Slotte, A Hinkkanen, and K Törnquist
Endocrinology. published 30 December 2008, 10.1210/en.2008-0625  [Abstract]

Parathyroid hormone decreases endothelial osteoprotegerin secretion: role of protein kinase A and C
Gloria Rashid, Eleanora Plotkin, Osnat Klein, Janice Green, Jacques Bernheim, and Sydney Benchetrit
Am J Physiol Renal Physiol. 2009; 296:F60-F66.  [Abstract] [Full Text] [PDF]

A Protein Kinase C-Dependent Protein Kinase D Pathway Modulates ERK1/2 and JNK1/2 Phosphorylation and Bim-Associated Apoptosis by Asbestos
Sylke A. Buder-Hoffmann, Arti Shukla, Trisha F. Barrett, Maximilian B. MacPherson, Karen M. Lounsbury, and Brooke T. Mossman
Am. J. Pathol. published 30 December 2008, 10.2353/ajpath.2009.080180  [Abstract]