2008-06

June 2008

Protein Kinase C Function in Muscle, Liver, and β-Cells and Its Therapeutic Implications for Type 2 Diabetes
Carsten Schmitz-Peiffer and Trevor J. Biden
Diabetes. 2008; 57:1774-1783. [Extract] [Full Text] [PDF]

Tauroursodeoxycholic acid exerts anticholestatic effects by a cooperative cPKC-/PKA-dependent mechanism in rat liver
Ralf Wimmer, Simon Hohenester, Thomas Pusl, Gerald U Denk, Christian Rust, and Ulrich Beuers
Gut. published 26 June 2008, 10.1136/gut.2007.140871 [Abstract]

PKC mutations in spinocerebellar ataxia type 14 affect C1 domain accessibility and kinase activity leading to aberrant MAPK signaling
Dineke S. Verbeek, Joachim Goedhart, Laurie Bruinsma, Richard J. Sinke, and Eric A. Reits
J. Cell Sci. published 24 June 2008, 10.1242/jcs.027698 [Abstract] [PDF]

CD44-EGFR interaction mediates hyaluronic acid-promoted cell motility by activating PKC signaling involving Akt, Rac1, Phox, ROS, FAK, and MMP-2
Youngmi Kim, Yun Sil Lee, Jongseon Choe, Hansoo Lee, Young Myeong Kim, and Dooil Jeoung
J. Biol. Chem. published 24 June 2008, 10.1074/jbc.M708319200 [Abstract] [PDF]

PKC-mediated phosphorylation controls budding of the pre-chylomicron transport vesicle
Shadab A. Siddiqi and Charles M. Mansbach II
J. Cell Sci. published 24 June 2008, 10.1242/jcs.022780 [Abstract] [PDF]

TOLL-LIKE RECEPTOR 3 TRIGGERS APOPTOSIS OF HUMAN PROSTATE CANCER CELLS THROUGH A PKC- DEPENDENT MECHANISM
Alessio Paone, Donatella Starace, Roberta Galli, Fabrizio Padula, Paola De Cesaris, Antonio Filippini, Elio Ziparo, and Anna Riccioli
Carcinogenesis. published 19 June 2008, 10.1093/carcin/bgn149 [Abstract] [PDF]

A Critical Role for Protein Kinase C--Mediated T Cell Survival in Cardiac Allograft Rejection
Santhakumar Manicassamy, Dengping Yin, Zheng Zhang, Luciana L. Molinero, Marisa-Luisa Alegre, and Zuoming Sun
J. Immunol. 2008; 181:513-520. [Abstract] [Full Text] [PDF]

Protein kinase C epsilon mediation of CRF- and ethanol-induced GABA release in central amygdala
Michal Bajo, Maureen T. Cruz, George R. Siggins, Robert Messing, and Marisa Roberto
PNAS. 2008; 105:8410-8415. [Abstract] [Full Text] [PDF]

CalDAG-GEFI and protein kinase C (PKC) represent alternative pathways leading to activation of integrin {alpha}IIb{beta}3 in platelets.
Stephen M Cifuni, Denisa D Wagner, and Wolfgang Bergmeier
Blood. 2008. [MEDLINE Citation]

Protein kinase C modulates inactivation of Kv3.3 channels.
Rooma Desai, Jack Kronengold, Jianfeng Mei, Stuart A Forman, and Leonard K Kaczmarek
J Biol Chem. 2008. [MEDLINE Citation]

Involvement of TTX-resistant Na+ current and protein kinase C in the action of GHRH on primary cultured somatotropes from GH-GFP transgenic mice.
Seung-Kwon Yang, Kun Wang, Helena Parkington, and Chen Chen
Endocrinology. 2008. [MEDLINE Citation]

Effects of corticosterone, cAMP, cGMP, Ca2+, and protein kinase C on apoptosis of mouse thymocytes induced by X-ray irradiation.
SL Gong, LH Dong, GW Liu, PS Gong, WT Lu, HG Zhao, XJ Jia, and Y Zhao
Biomed Environ Sci. 2008; 21: 167. [MEDLINE Citation]

The overexpression and altered localization of the atypical protein kinase C lambda/iota in breast cancer correlates with the pathologic type of these tumors.
Y Kojima, K Akimoto, Y Nagashima, H Ishiguro, S Shirai, T Chishima, Y Ichikawa, T Ishikawa, T Sasaki, Y Kubota, Y Inayama, I Aoki, S Ohno, and H Shimada
Hum Pathol. 2008; 39: 824. [MEDLINE Citation]

Resveratrol attenuates adenosine diphosphate-induced platelet activation by reducing protein kinase C activity.
YM Yang, XX Wang, JZ Chen, SJ Wang, H Hu, and HQ Wang
Am J Chin Med. 2008; 36: 603. [MEDLINE Citation]

MARCKS Regulation of Mucin Secretion by Airway Epithelium in Vitro: Interaction with Chaperones
Joungjoa Park, Shijing Fang, Anne L. Crews, Ko-Wei Lin, and Kenneth B. Adler
Am. J. Respir. Cell Mol. Biol. 2008; 39:68-76. [Abstract] [Full Text] [PDF]

Protein Kinase D Links G_q-coupled Receptors to cAMP Response Element-binding Protein (CREB)-Ser¹³³ Phosphorylation in the Heart
Nazira Ozgen, Maria Obreztchikova, Jianfen Guo, Hasnae Elouardighi, Gerald W. Dorn, II, Brenda A. Wilson, and Susan F. Steinberg
J. Biol. Chem. 2008; 283:17009-17019. [Abstract] [Full Text] [PDF]

Tyrosine phosphorylation modifies PKC-dependent phosphorylation of cardiac troponin I
Marius P. Sumandea, Vitalyi O. Rybin, Aaron C. Hinken, Chaojian Wang, Tomoyoshi Kobayashi, Erin Harleton, Gail Sievert, C. William Balke, Steven J. Feinmark, R. John Solaro, and Susan F. Steinberg
J. Biol. Chem. published 12 June 2008, 10.1074/jbc.M802396200 [Abstract] [PDF]

The major chemical detoxifying system of UDP- glucuronosyltransferases requires regulated phosphorylation supported by protein kinase C
Nikhil K. Basu, Labanyamoy Kole, Mousumi Basu, Kushal Chakraborty, Partha S. Mitra, and Ida S. Owens
J. Biol. Chem. published 13 June 2008, 10.1074/jbc.M800032200 [Abstract] [PDF]

HMG-CoA reductase inhibitors activate the unfolded protein response and induce cytoprotective GRP78 expression
Jui-Ching Chen, Mei-Lin Wu, Kuo-Chin Huang, and Wan-Wan Lin
Cardiovasc Res. published 12 June 2008, 10.1093/cvr/cvn160 [Abstract] [PDF]

Signaling and Cross-talk by C5a and UDP in Macrophages Selectively Use PLCβ3 to Regulate Intracellular Free Calcium
Tamara I. A. Roach, Robert A. Rebres, Iain D. C. Fraser, Dianne L. DeCamp, Keng-Mean Lin, Paul C. Sternweis, Mel I. Simon, and William E. Seaman
J. Biol. Chem. 2008; 283:17351-17361. [Abstract] [Full Text] [PDF]

Phosphorylation of Protein Kinase C on Distinct Tyrosine Residues Induces Sustained Activation of Erk1/2 via Down-regulation of MKP-1: ROLE IN THE APOPTOTIC EFFECT OF ETOPOSIDE
Stephanie L. Lomonaco, Sarit Kahana, Michal Blass, Yehuda Brody, Hana Okhrimenko, Cunli Xiang, Susan Finniss, Peter M. Blumberg, Hae-Kyung Lee, and Chaya Brodie
J. Biol. Chem. 2008; 283:17731-17739. [Abstract] [Full Text] [PDF]

PKC acts upstream of SPAK in the activation of NKCC1 by hyperosmomtic stress in airway epithelial cells
Laura Smith, Nicole Smallwood, Amnon Altman, and Carole M. Liedtke
J. Biol. Chem. published 11 June 2008, 10.1074/jbc.M801752200 [Abstract] [PDF]

The novel protein kinase C isoforms - and - modulate caerulein-induced zymogen activation in pancreatic acinar cells
Edwin C. Thrower, Sara Osgood, Christine A. Shugrue, Thomas R. Kolodecik, Anamika M. Chaudhuri, Joseph R. Reeve, Jr, Stephen J. Pandol, and Fred S. Gorelick
Am J Physiol Gastrointest Liver Physiol. 2008; 294:G1344-G1353. [Abstract] [Full Text] [PDF]

Complex regulation of store-operated Ca²⁺ entry pathway by PKC- in vascular SMCs
Tarik Smani, Tina Patel, and Victoria M. Bolotina
Am J Physiol Cell Physiol. 2008; 294:C1499-C1508. [Abstract] [Full Text] [PDF]

Hypothalamic PKC regulates Glucose Production.
Rachel Ross, Penny Y T Wang, Madhu Chari, Carol K L Lam, Liora Caspi, Hiraku Ono, Evan D Muse, Xiaosong Li, Roger Gutierrez-Juarez, Peter E Light, Gary J Schwartz, Luciano Rossetti, and Tony K T Lam
Diabetes. 2008. [MEDLINE Citation]

Novel PKC signaling is required for LPS-induced soluble Flt-1 expression in macrophages.
Ming-Cheng Lee, Shu-Chen Wei, Jyy-Jih Tsai-Wu, C H Herbert Wu, and Po-Nien Tsao
J Leukoc Biol. 2008. [MEDLINE Citation]

Rosiglitazone Improves Aortic Arginine Transport, Through Inhibition of PKC{alpha}, in Uremic Rats.
Merav Ingbir, Idit F Schwartz, Alexander Shtabsky, Irina Filip, Ran Reshef, Tamara Chernichovski, Naumi Levine Iaina, Uri Rozovski, Yoram Levo, and Doron Schwartz
Am J Physiol Renal Physiol. 2008. [MEDLINE Citation]

PKC isotype functions in T lymphocytes.
G Baier
Ernst Schering Found Symp Proc. 2007; : 29. [MEDLINE Citation]

PKC putative phosphorylation site Ser235 is required for MIP/AQP0 translocation to the plasma membrane.
N Golestaneh, J Fan, P Zelenka, and AB Chepelinsky
Mol Vis. 2008; 14: 1006. [MEDLINE Citation]

Protein Kinase C Binds Peripherin and Induces Its Aggregation, Which Is Accompanied by Apoptosis of Neuroblastoma Cells
Lovisa Sunesson, Ulf Hellman, and Christer Larsson
J. Biol. Chem. 2008; 283:16653-16664. [Abstract] [Full Text] [PDF]

Interaction of ₁-Adrenoceptor Subtypes With Different G Proteins Induces Opposite Effects on Cardiac L-type Ca²⁺ Channel
Jin O-Uchi, Hiroyuki Sasaki, Satoshi Morimoto, Yoichiro Kusakari, Hitomi Shinji, Toru Obata, Kenichi Hongo, Kimiaki Komukai, and Satoshi Kurihara
Circ. Res. 2008; 102:1378-1388. [Abstract] [Full Text] [PDF]

Original Research: Role of phosphodiesterases in modulation of BK_Ca channels in hypertensive pulmonary arterial smooth muscle
Shu Zhu, Richard E. White, and Scott A. Barman
Therapeutic Advances in Respiratory Disease. 2008; 2:119-127. [Abstract] [PDF]

Involvement of TTX-resistant Na⁺ current and protein kinase C in the action of GHRH on primary cultured somatotropes from GH-GFP transgenic mice
Seung-Kwon Yang, Kun Wang, Helena Parkington, and Chen Chen
Endocrinology. published 5 June 2008, 10.1210/en.2008-0405 [Abstract]

Coordinated phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 and protein kinase CβII in the diabetic fat tissue
Ziva Liberman, Batya Plotkin, Tamar Tennenbaum, and Hagit Eldar-Finkelman
Am J Physiol Endocrinol Metab. 2008; 294:E1169-E1177. [Abstract] [Full Text] [PDF]

Rosiglitazone Improves Aortic Arginine Transport, Through Inhibition of PKC, in Uremic Rats
Merav Ingbir, Idit F Schwartz, Alexander Shtabsky, Irina Filip, Ran Reshef, Tamara Chernichovski, Naumi Levine Iaina, Uri Rozovski, Yoram Levo, and Doron Schwartz
Am J Physiol Renal Physiol. published 4 June 2008, 10.1152/ajprenal.00619.2007 [Abstract] [PDF]

Demonstration of the essential role of protein kinase C isoforms in hyperglycemia-induced embryonic malformations.
Zhiyong Zhao, YK Wu, and EA Reece
Reprod Sci. 2008; 15: 349. [MEDLINE Citation]

A PHYSIOLOGICAL ROLE FOR PHOSPHATIDIC ACID IN THE TRANSLOCATION OF THE NOVEL PROTEIN KINASE C APL II IN APLYSIA NEURONS.
Carole A Farah, Ikue Nagakura, Daniel Weatherill, Xiaotang Fan, and Wayne S Sossin
Mol Cell Biol. 2008. [MEDLINE Citation]

Comment on: Thallas-Bonke et al. (2008) Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product-Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-{alpha}-Dependent Pathway: Diabetes 57:460-469, 2008.
S Yamagishi
Diabetes. 2008; 57: e13. [MEDLINE Citation]

Response to Comment on: Thallas-Bonke et al. (2008) Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product-Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-{alpha}-Dependent Pathway: Diabetes 57:460-469, 2008.
Vicki Thallas-Bonke and Josephine M Forbes
Diabetes. 2008; 57: e14. [MEDLINE Citation]

PHLPPing the switch on Akt and protein kinase C signaling.
John Brognard and Alexandra C Newton
Trends Endocrinol Metab. 2008. [MEDLINE Citation]

Counter Regulatory Effects of PKC{beta}II and PKC{delta} on Coronary Endothelial Permeability.
Nathalie Gaudreault, Rachel M Perrin, Mingzang Guo, Chase P Clanton, Mack H Wu, and Sarah Y Yuan
Arterioscler Thromb Vasc Biol. 2008. [MEDLINE Citation]

PKC promotes proliferation of airway smooth muscle cells by regulating cyclinD1 expression in asthmatic rats.
LF Qiao, YJ Xu, XS Liu, SX Chen, JG Xie, J Wang, CL Du, J Zhang, W Ni, and SX Chen
Acta Pharmacol Sin. 2008; 29: 677. [MEDLINE Citation]

Modulation of erythrocyte deformability by PKC activity.
S de Oliveira, AS Silva-Herdade, and C Saldanha
Clin Hemorheol Microcirc. 2008; 39: 363. [MEDLINE Citation]

Inhibition of PKCalpha activation in human bone and soft tissue sarcoma cells by the selective PKC inhibitor PKC412.
T Kawamoto, T Akisue, K Kishimoto, H Hara, M Imabori, T Fujimoto, M Kurosaka, T Hitora, Y Kawaguchi, and T Yamamoto
Anticancer Res. 2008; 28: 825. [MEDLINE Citation]

PKC isotype functions in T lymphocytes.
G Baier
Ernst Schering Found Symp Proc. 2007; : 29. [MEDLINE Citation]

Signaling pathways involved in sphingosine kinase activation and sphingosine-1-phosphate release in rat myometrium in late pregnancy: role in the induction of COX2.
Martin Serrano-Sanchez, Zahra Tanfin, and Denis Leiber
Endocrinology. 2008. [MEDLINE Citation]

Fluid flow induces mechanosensitive ATP release, calcium signalling and Cl^– transport in biliary epithelial cells through a PKC-dependent pathway
Kangmee Woo, Amal K. Dutta, Vishal Patel, Charles Kresge, and Andrew P. Feranchak
J. Physiol. 2008; 586:2779-2798. [Abstract] [Full Text] [PDF]

Identifying the targets of the amplifying pathway for insulin secretion in pancreatic beta cells by kinetic modeling of granule exocytosis
Yi-der Chen, Shaokun Wang, and Arthur Sherman
Biophys. J. published 30 May 2008, 10.1529/biophysj.107.124990 [Abstract]