October 2008

October 2008

Negative Regulation of Class IA Phosphoinositide 3-kinase by Protein Kinase C ${delta}$ Limits Fc ${gamma}$ Receptor-mediated Phagocytosis in Macrophages
Kaoru Hazeki, Kazumi Inoue, Kiyomi Nigorikawa, and Osamu Hazeki
J. Biochem. published 30 October 2008, 10.1093/jb/mvn142 [Abstract] [PDF]

Phosphorylation of Farnesoid X Receptor by Protein Kinase C Promotes Its Transcriptional Activity
Romain Gineste, Audrey Sirvent, Réjane Paumelle, Stéphane Helleboid, Alexis Aquilina, Raphaël Darteil, Dean W. Hum, Jean-Charles Fruchart, and Bart Staels
Mol. Endocrinol. 2008; 22:2433-2447. [Abstract] [Full Text] [PDF]

PKC ${zeta}$ represses the IL-6 promoter and impairs tumorigenesis in vivo
Anita S. Galvez, Angeles Duran, Juan F. Linares, Peterson Pathrose, Elias A. Castilla, Shadi Abu-Baker, Michael Leitges, Maria T. Diaz-Meco, and Jorge Moscat
Mol. Cell. Biol. published 27 October 2008, 10.1128/MCB.01294-08 [Abstract] [PDF]

Protein kinase C activation stabilizes LDL receptor mRNA via the JNK pathway in HepG2 cells.
Noelle B Vargas, Brandy Y Brewer, Terry B Rogers, and Gerald M Wilson
J Lipid Res. 2008. [MEDLINE Citation]

The Effect of Protein Kinase C {beta} Inhibition on Renal Hemodynamic Function and Urinary Biomarkers in Humans with Type 1 Diabetes Mellitus: A Pilot Study.
David Z I Cherney, Ana Konvalinka, Bernard Zinman, Eleftherios P Diamandis, Anton Soosaipillai, Heather Reich, Joanne Lorraine, Vesta Lai, James W Scholey, and Judith A Miller
Diabetes Care. 2008. [MEDLINE Citation]

Protein Kinase C-related Kinase and ROCK Are Required for Thrombin-induced Endothelial Cell Permeability Downstream from G ${alpha}$ 12/13 and G ${alpha}$ _11/q
Julie Gavard and J. Silvio Gutkind
J. Biol. Chem. 2008; 283:29888-29896. [Abstract] [Full Text] [PDF]

Delta Protein Kinase C Interacts with the d Subunit of the F₁F₀ ATPase in Neonatal Cardiac Myocytes Exposed to Hypoxia or Phorbol Ester: IMPLICATIONS FOR F₁F₀ ATPase REGULATION
Tiffany Nguyen, Mourad Ogbi, and John A. Johnson
J. Biol. Chem. 2008; 283:29831-29840. [Abstract] [Full Text] [PDF]

Direct Association of Calponin with Specific Domains of PKC ${alpha}$
Sita Somara and Khalil N. Bitar
Am J Physiol Gastrointest Liver Physiol. published 23 October 2008, 10.1152/ajpgi.90461.2008 [Abstract] [PDF]

PKC ${eta}$ directs induction of IRF-4 expression and Ig ${kappa}$ gene rearrangement in pre-BCR signaling pathway
Akihisa Oda, Tomohiro Ono, Mutsumi Yamamoto, Ryo Goitsuka, and Daisuke Kitamura
Int. Immunol. 2008; 20:1417-1426. [Abstract] [Full Text] [PDF]

Modulation of transient and persistent inward currents by activation of protein kinase C in spinal ventral neurons of the neonatal rat
Yue Dai, Larry M. Jordan, and Brent Fedirchuk
J Neurophysiol. published 22 October 2008, 10.1152/jn.01373.2007 [Abstract] [PDF]

The Effect of Protein Kinase C β Inhibition on Renal Hemodynamic Function and Urinary Biomarkers in Humans with Type 1 Diabetes Mellitus: A Pilot Study
David Z.I. Cherney, Ana Konvalinka, Bernard Zinman, Eleftherios P. Diamandis, Anton Soosaipillai, Heather Reich, Joanne Lorraine, Vesta Lai, James W. Scholey, and Judith A. Miller
Diabetes Care. published 22 October 2008, 10.2337/dc08-1609 [Abstract] [PDF]

Nonclassical Mechanisms of Progesterone Action in the Brain: I. Protein Kinase C Activation in the Hypothalamus of Female Rats
Bhuvana Balasubramanian, Wendy Portillo, Andrea Reyna, Jian Zhong Chen, Anthony N. Moore, Pramod K. Dash, and Shaila K. Mani
Endocrinology. 2008; 149:5509-5517. [Abstract] [Full Text] [PDF]

Loss of Protein Kinase C ${theta}$ , Bcl10, or Malt1 Selectively Impairs Proliferation and NF- ${kappa}$ B Activation in the CD4⁺ T Cell Subset
Lara M. Kingeter and Brian C. Schaefer
J. Immunol. 2008; 181:6244-6254. [Abstract] [Full Text] [PDF]

Locally generated methylseleninic acid induces specific inactivation of protein kinase C isoenzymes: Relevance to selenium-induced apoptosis in prostate cancer cells.
Usha Gundimeda, Jason Eric Schiffman, Divya Chhabra, Jourdan Wong, Adela Wu, and Rayudu Gopalakrishna
J Biol Chem. 2008. [MEDLINE Citation]

Nicotine Promotes Mammary Tumor Migration via a Signaling Cascade Involving Protein Kinase C and cdc42
Jinjin Guo, Soichiro Ibaragi, Tongbo Zhu, Ling-Yu Luo, Guo-Fu Hu, Petra S. Huppi, and Chang Yan Chen
Cancer Res. 2008; 68:8473-8481. [Abstract] [Full Text] [PDF]

Structural Basis of Protein Kinase C Isoform Function
Susan F. Steinberg
Physiol Rev. 2008; 88:1341-1378. [Abstract] [Full Text] [PDF]

Protein kinase c contributes to the maintenance of contractile force in human ventricular cardiomyocytes
Andrea Molnár, Attila Borbély, Dániel Czuriga, Ivetta M. Siket, Szabolcs Szilágyi, Zita Hertelendi, Eniko T. Pásztor, Zoltán Galajda, Tamás Szerafin, Kornelia Jaquet, Zoltán Papp, István Édes, and Attila Tóth
J. Biol. Chem. published 14 October 2008, 10.1074/jbc.M807600200 [Abstract] [PDF]

Protein kinase C- and reactive oxygen species-dependent stimulation of intracellular cAMP in human eosinophils. The role of extracellular signal-regulated protein kinases.
CI Ezeamuzie and N Taslim
Med Princ Pract. 2008; 17: 468. [MEDLINE Citation]

Differential requirement of PKC-theta in the development and function of natural regulatory T cells.
Sonal Gupta, Santhakumar Manicassamy, Chenthamarakshan Vasu, Anvita Kumar, Weirong Shang, and Zuoming Sun
Mol Immunol. 2008. [MEDLINE Citation]

Ca(2+) oscillation induced by P2Y2 receptor activation and its regulation by a neuron-specific subtype of PKC (gammaPKC).
Noriaki Ashida, Takehiko Ueyama, Kyoko Rikitake, Yasuhito Shirai, Mika Eto, Takeshi Kondoh, Eiji Kohmura, and Naoaki Saito
Neurosci Lett. 2008. [MEDLINE Citation]

Novel roles for protein kinase C $delta$ -dependent signaling pathways in acute hypoxic stress-induced autophagy
Jo-Lin Chen, Her H. Lin, Kwang-Jin Kim, Anning Lin, Henry J. Forman, and David K. Ann
J. Biol. Chem. published 3 October 2008, 10.1074/jbc.M804239200 [Abstract] [PDF]

Loss of protein kinase C{epsilon} results in impaired cutaneous wound closure and myofibroblast function.
Andrew Leask, Xu Shi-Wen, Korsa Khan, Yunliang Chen, Alan Holmes, Mark Eastwood, Christopher P Denton, Carol M Black, and David J Abraham
J Cell Sci. 2008. [MEDLINE Citation]

Organic anion transporter OAT1 undergoes constitutive and protein kinase C-regulated trafficking through a dynamin- and clathrin-dependent pathway.
Qiang Zhang, Mei Hong, Peng Duan, Zui Pan, Jianjie Ma, and Guofeng You
J Biol Chem. 2008. [MEDLINE Citation]

PRIMARY CLEARANCE OF MURINE GAMMAHERPESVIRUS-68 (MHV-68) BY PROTEIN KINASE C {theta} (PKC{theta}) -/- CD8 T CELLS IS COMPROMISED IN THE ABSENCE OF CD4 T CELL HELP.
Peter Dias, Ashley L Shea, Chandra Inglis, Francesca Giannoni, Lian Ni Lee, and Sally R Sarawar
J Virol. 2008. [MEDLINE Citation]

Interaction between protein kinase C and protein kinase A can modulate transmitter release at the rat neuromuscular synapse.
M M Santafe, N Garcia, M A Lanuza, M Tomas, and J Tomas
J Neurosci Res. 2008. [MEDLINE Citation]

Prostaglandin E₂ Signals Monocyte/Macrophage Survival to Peroxynitrite via Protein Kinase A Converging in Bad Phosphorylation with the Protein Kinase C ${alpha}$ -Dependent Pathway Driven by 5-Hydroxyeicosatetraenoic Acid
Ilaria Tommasini, Liana Cerioni, Letizia Palomba, and Orazio Cantoni
J. Immunol. 2008; 181:5637-5645. [Abstract] [Full Text] [PDF]

Visualizing the temporal effects of vasoconstrictors on PKC translocation and Ca²⁺ signaling in single resistance arterial smooth muscle cells
Carl P. Nelson, Jonathon M. Willets, Noel Wyn Davies, R.A. John Challiss, and Nicholas B. Standen
Am J Physiol Cell Physiol. published 1 October 2008, 10.1152/ajpcell.00365.2008 [Abstract] [PDF]

CD28 stimulation triggers NF- ${kappa}$ B activation through the CARMA1–PKC ${theta}$ –Grb2/Gads axis
Kei Takeda, Yohsuke Harada, Ryosuke Watanabe, Yuu Inutake, Shuhei Ogawa, Kazunobu Onuki, Saori Kagaya, Kazunari Tanabe, Hidehiro Kishimoto, and Ryo Abe
Int. Immunol. published 1 October 2008, 10.1093/intimm/dxn108 [Abstract] [Full Text] [PDF]

EGF Stimulates Goblet Cell Proliferation Using cPKC ${alpha}$ and nPKC ${epsilon}$
Marie A. Shatos, Robin R. Hodges, Yoshia Oshi, Jeffrey A. Bair, Driss Zoukhri, Claire L Kublin, Kameran Lashkari, and Darlene A. Dartt
Invest. Ophthalmol. Vis. Sci. published 29 September 2008, 10.1167/iovs.08-2467 [Abstract