May 2008

Novel PKC signaling is required for LPS-induced soluble Flt-1 expression in macrophages
Ming-Cheng Lee, Shu-Chen Wei, Jyy-Jih Tsai-Wu, C.H. Herbert Wu, and Po-Nien Tsao
J. Leukoc. Biol. published 29 May 2008, 10.1189/jlb.1007691  [Abstract]

Fluid flow induces mechanosensitive ATP release, calcium signalling and Cl– transport in biliary epithelial cells through a PKC{zeta}-dependent pathway
Kangmee Woo, Amal K. Dutta, Vishal Patel, Charles Kresge, and Andrew P. Feranchak
J. Physiol. 2008; 586:2779-2798.  [Abstract] [Full Text] [PDF]

Protein Kinase C{alpha}-Induced Derepression of the Human Luteinizing Hormone Receptor Gene Transcription through ERK-Mediated Release of HDAC1/Sin3A Repressor Complex from Sp1 Sites
Mingjuan Liao, Ying Zhang, and Maria L. Dufau
Mol. Endocrinol. 2008; 22:1449-1463.  [Abstract] [Full Text] [PDF]

Protein Kinase C{alpha}-Induced Derepression of the Human Luteinizing Hormone Receptor Gene Transcription through ERK-Mediated Release of HDAC1/Sin3A Repressor Complex from Sp1 Sites
Mingjuan Liao, Ying Zhang, and Maria L. Dufau
Mol. Endocrinol. 2008; 22:1449-1463.  [Abstract] [Full Text] [PDF]

Mechanisms related to the cardioprotective effects of protein kinase C epsilon (PKC varepsilon) peptide activator or inhibitor in rat ischemia/reperfusion injury.
Jane Chun-Wen Teng, Helen Kay, Qian Chen, Jovan S Adams, Christopher Grilli, Giuseppe Guglielmello, Christopher Zambrano, Samuel Krass, Adrian Bell, and Lindon H Young
Naunyn Schmiedebergs Arch Pharmacol. 2008. [MEDLINE Citation]

Diacylglycerol kinase-{varepsilon} restores cardiac dysfunction under chronic pressure overload: A new specific regulator of G{alpha}q signaling cascade.
Takeshi Niizeki, Yasuchika Takeishi, Tatsuro Kitahara, Takanori Arimoto, Mitsunori Ishino, Olga Bilim, Satoshi Suzuki, Toshiki Sasaki, Osamu Nakajima, Richard A Walsh, Kaoru Goto, and Isao Kubota
Am J Physiol Heart Circ Physiol. 2008. [MEDLINE Citation]

Activation of the spinal sigma-1 receptor enhances NMDA-induced pain via PKC- and PKA-dependent phosphorylation of the NR1 subunit in mice.
H-W Kim, D-H Roh, S-Y Yoon, H-S Seo, Y-B Kwon, H-J Han, K-W Kim, A J Beitz, and J-H Lee
Br J Pharmacol. 2008. [MEDLINE Citation]

Probable involvement of epsilon-isoform of protein kinase C in rat bronchial smooth muscle contraction induced by acetylcholine.
H Sakai, M Yamamoto, Y Chiba, and M Misawa
J Smooth Muscle Res. 2008; 44: 9. [MEDLINE Citation]

Counter Regulatory Effects of PKC{beta}II and PKC{delta} on Coronary Endothelial Permeability
Nathalie Gaudreault, Rachel M. Perrin, Mingzang Guo, Chase P. Clanton, Mack H. Wu, and Sarah Y. Yuan
Arterioscler. Thromb. Vasc. Biol. published 22 May 2008, 10.1161/ATVBAHA.108.166975  [Abstract] [PDF]

Protein Kinase C{theta} Is Required for Autophagy in Response to Stress in the Endoplasmic Reticulum
Kenjiro Sakaki, Jun Wu, and Randal J. Kaufman
J. Biol. Chem. 2008; 283:15370-15380.  [Abstract] [Full Text] [PDF]

Enzymological analysis of mutant protein kinase Cgamma causing spinocerebellar ataxia type 14 and dysfunction in Ca2+ homeostasis
Naoko Adachi, Takeshi Kobayashi, Hideyuki Takahashi, Takumi Kawasaki, Yasuhito Shirai, Takehiko Ueyama, Toshio Matsuda, Takahiro Seki, Norio Sakai, and Naoaki Saito
J. Biol. Chem. published 22 May 2008, 10.1074/jbc.M801492200  [Abstract] [PDF]

Demonstration of the Essential Role of Protein Kinase C Isoforms in Hyperglycemia-Induced Embryonic Malformations
Zhiyong Zhao, Ying-King Wu, and E. Albert Reece
Reproductive Sciences. 2008; 15:349-356.  [Abstract] [PDF]

Protein Kinase C{theta} Is Required for Autophagy in Response to Stress in the Endoplasmic Reticulum
Kenjiro Sakaki, Jun Wu, and Randal J. Kaufman
J. Biol. Chem. 2008; 283:15370-15380.  [Abstract] [Full Text] [PDF]

Demonstration of the Essential Role of Protein Kinase C Isoforms in Hyperglycemia-Induced Embryonic Malformations
Zhiyong Zhao, Ying-King Wu, and E. Albert Reece
Reproductive Sciences. 2008; 15:349-356.  [Abstract] [PDF]

Hypoxia exposure induces the emergence of fibroblasts lacking replication repressor signals of PKC{zeta} in the pulmonary artery adventitia
Mita Das, Nana Burns, Shelly J. Wilson, Wojciech M. Zawada, and Kurt R. Stenmark
Cardiovasc Res. 2008; 78:440-448.  [Abstract] [Full Text] [PDF]

Plakophilin 2: a critical scaffold for PKC{alpha} that regulates intercellular junction assembly
Amanda E. Bass-Zubek, Ryan P. Hobbs, Evangeline V. Amargo, Nicholas J. Garcia, Sherry N. Hsieh, Xinyu Chen, James K. Wahl, III, Mitchell F. Denning, and Kathleen J. Green
J. Cell Biol. 2008; 181:605-613.  [Abstract] [Full Text] [PDF]

Pulmonary hyperplasia and the two sides of PKC{zeta}
Kristof Graf
Cardiovasc Res. 2008; 78:409-410.  [Extract] [Full Text] [PDF]

Protein Kinase D3 (PKD3) Contributes to Prostate Cancer Cell Growth and Survival Through a PKC{varepsilon}/PKD3 Pathway Downstream of Akt and ERK 1/2
Jun Chen, Fan Deng, Shivendra V. Singh, and Qiming J. Wang
Cancer Res. 2008; 68:3844-3853.  [Abstract] [Full Text] [PDF]

PKC enhances tight junction barrier function of human nasal epithelial cells in primary culture by transcriptional regulation
Jun-ichi Koizumi, Takashi Kojima, Noriko Ogasawara, Ryuta Kamekura, Makoto Kurose, Mitsuru Go, Atsushi Harimaya, Masaki Murata, Makoto Osanai, Hideki Chiba, Tetsuo Himi, and Norimasa Sawada
Mol. Pharmacol. published 13 May 2008, 10.1124/mol.107.043711  [Abstract] [PDF]

Plakophilin 2: a critical scaffold for PKC{alpha} that regulates intercellular junction assembly
Amanda E. Bass-Zubek, Ryan P. Hobbs, Evangeline V. Amargo, Nicholas J. Garcia, Sherry N. Hsieh, Xinyu Chen, James K. Wahl, III, Mitchell F. Denning, and Kathleen J. Green
J. Cell Biol. published 12 May 2008, 10.1083/jcb.200712133  [Abstract] [Full Text] [PDF]

Curcumin decreases 12-0-tetradecanoylphorbol-13-acetate-induced protein kinase C translocation to modulate downstream targets in mouse skin
Rachana Garg, Asha Ramchandani, and Girish Maru
Carcinogenesis. published 13 May 2008, 10.1093/carcin/bgn114  [Abstract] [PDF]

The scaffold MYD88 acts to couple protein kinase C epsilon (PKCepsilon ) to toll-like receptors.
Amir Faisal, Adrian Saurin, Bernard Gregory, Brian Foxwell, and Peter J Parker
J Biol Chem. 2008. [MEDLINE Citation]

Dual regulation of the cardiac L-type calcium channel in L6 cells by protein kinase C.
Bashir A Tafti and Basil M Hantash
Cell Calcium. 2008. [MEDLINE Citation]

Spike Timing-Dependent Long-Term Potentiation in Ventral Tegmental Area Dopamine Cells Requires PKC.
Percy Luu and Robert C Malenka
J Neurophysiol. 2008. [MEDLINE Citation]

Stimulation of the neurokinin 3 receptor activates protein kinase C{varepsilon} and protein kinase D in enteric neurons
D. P. Poole, S. Amadesi, E. Rozengurt, M. Thacker, N. W. Bunnett, and J. B. Furness
Am J Physiol Gastrointest Liver Physiol. 2008; 294:G1245-G1256.  [Abstract] [Full Text] [PDF]

Prolactin stimulates transepithelial calcium transport and modulates paracellular permselectivity in Caco-2 monolayer: mediation by PKC and ROCK pathways
Narongrit Thongon, La-iad Nakkrasae, Jirawan Thongbunchoo, Nateetip Krishnamra, and Narattaphol Charoenphandhu
Am J Physiol Cell Physiol. 2008; 294:C1158-C1168.  [Abstract] [Full Text] [PDF]

Stimulation of the neurokinin 3 receptor activates protein kinase C{varepsilon} and protein kinase D in enteric neurons
D. P. Poole, S. Amadesi, E. Rozengurt, M. Thacker, N. W. Bunnett, and J. B. Furness
Am J Physiol Gastrointest Liver Physiol. 2008; 294:G1245-G1256.  [Abstract] [Full Text] [PDF]

Regulation of H2O2-induced necrosis by Protein Kinase C and AMP-activated kinase signaling in primary cultured hepatocytes
Behnam Saberi, Mie Shinohara, Maria D Ybanez, Naoko Hanawa, William Gaarde, Neil Kaplowitz, and Derick Han, PhD
Am J Physiol Cell Physiol. published 7 May 2008, 10.1152/ajpcell.90654.2007  [Abstract] [PDF]

The scaffold MYD88 acts to couple protein kinase C epsilon (PKCepsilon ) to toll-like receptors
Amir Faisal, Adrian Saurin, Bernard Gregory, Brian Foxwell, and Peter J. Parker
J. Biol. Chem. published 5 May 2008, 10.1074/jbc.M710330200  [Abstract] [PDF]

Sequential Protein Kinase C (PKC)-dependent and PKC-independent Protein Kinase D Catalytic Activation via Gq-coupled Receptors: DIFFERENTIAL REGULATION OF ACTIVATION LOOP SER744 AND SER748 PHOSPHORYLATION
Rodrigo Jacamo, James Sinnett-Smith, Osvaldo Rey, Richard T. Waldron, and Enrique Rozengurt
J. Biol. Chem. 2008; 283:12877-12887.  [Abstract] [Full Text] [PDF]

Protein kinase C inhibits caveolae-mediated endocytosis of TRPV5
Seung-Kuy Cha, Tao Wu, and Chou-Long Huang
Am J Physiol Renal Physiol. 2008; 294:F1212-F1221.  [Abstract] [Full Text] [PDF]

Complex regulation of store-operated Ca2+ entry pathway by PKC{epsilon} in vascular SMC.
Tarik Smani, Tina Patel, and Victoria M Bolotina
Am J Physiol Cell Physiol. 2008. [MEDLINE Citation]

Protein kinase C {delta} mediates neuronal apoptosis in the retinas of diabetic rats via the Akt signaling pathway.
Young-Hee Kim, Yoon-Sook Kim, Chang-Hwan Park, In-Yong Chung, Ji-Myong Yoo, Jae-Geun Kim, Byung-Ju Lee, Sang-Soo Kang, Gyeong-Jae Cho, and Wan-Sung Choi
Diabetes. 2008. [MEDLINE Citation]

Epidermal growth factor receptor activation by protein kinase C is necessary for FSH-induced meiotic resumption in porcine cumulus-oocyte complexes.
X Chen, B Zhou, J Yan, B Xu, P Tai, J Li, S Peng, M Zhang, and G Xia
J Endocrinol. 2008; 197: 409. [MEDLINE Citation]

IGF-II/mannose-6-phosphate receptor signaling induced cell hypertrophy and atrial natriuretic peptide/BNP expression via Galphaq interaction and protein kinase C-alpha/CaMKII activation in H9c2 cardiomyoblast cells.
CH Chu, BS Tzang, LM Chen, CH Kuo, YC Cheng, LY Chen, FJ Tsai, CH Tsai, WW Kuo, and CY Huang
J Endocrinol. 2008; 197: 381. [MEDLINE Citation]

Deletion of toll-like receptor-4 downregulates protein kinase C-zeta and attenuates liver injury in experimental pancreatitis.
Y Peng, CA Sigua, D Rideout, and MM Murr
Surgery. 2008; 143: 679. [MEDLINE Citation]

Protein kinase C: a target for therapy in pancreatic cancer.
BF El-Rayes, S Ali, PA Philip, and FH Sarkar
Pancreas. 2008; 36: 346. [MEDLINE Citation]

Protein kinase C {delta} mediates neuronal apoptosis in the retinas of diabetic rats via the Akt signaling pathway.
Young-Hee Kim, Yoon-Sook Kim, Chang-Hwan Park, In-Yong Chung, Ji-Myong Yoo, Jae-Geun Kim, Byung-Ju Lee, Sang-Soo Kang, Gyeong-Jae Cho, and Wan-Sung Choi
Diabetes. 2008. [MEDLINE Citation]

Epidermal growth factor receptor activation by protein kinase C is necessary for FSH-induced meiotic resumption in porcine cumulus-oocyte complexes.
X Chen, B Zhou, J Yan, B Xu, P Tai, J Li, S Peng, M Zhang, and G Xia
J Endocrinol. 2008; 197: 409. [MEDLINE Citation]

IGF-II/mannose-6-phosphate receptor signaling induced cell hypertrophy and atrial natriuretic peptide/BNP expression via Galphaq interaction and protein kinase C-alpha/CaMKII activation in H9c2 cardiomyoblast cells.
CH Chu, BS Tzang, LM Chen, CH Kuo, YC Cheng, LY Chen, FJ Tsai, CH Tsai, WW Kuo, and CY Huang
J Endocrinol. 2008; 197: 381. [MEDLINE Citation]

Protein kinase C: a target for therapy in pancreatic cancer.
BF El-Rayes, S Ali, PA Philip, and FH Sarkar
Pancreas. 2008; 36: 346. [MEDLINE Citation]

CaM kinase II and protein kinase C activations mediate enhancement of long-term potentiation by nefiracetam in the rat hippocampal CA1 region.
Shigeki Moriguchi, Norifumi Shioda, Feng Han, Toshio Narahashi, and Kohji Fukunaga
J Neurochem. 2008. [MEDLINE Citation]

Deletion of toll-like receptor-4 downregulates protein kinase C-zeta and attenuates liver injury in experimental pancreatitis.
Y Peng, CA Sigua, D Rideout, and MM Murr
Surgery. 2008; 143: 679. [MEDLINE Citation]

The angiotensin receptor type 1–Gq protein–phosphatidyl inositol phospholipase C¥â–protein kinase C pathway is involved in activation of proximal tubule Na+-ATPase activity by angiotensin(1–7) in pig kidneys
Lucienne S. Lara, Juliana S. Correa, Anouchka B. Lavelle, Anibal G. Lopes, and Celso Caruso-Neves
Exp Physiol. 2008; 93:639-647.  [Abstract] [Full Text] [PDF]

Protein kinase C inhibits caveolae-mediated endocytosis of TRPV5
Seung-Kuy Cha, Tao Wu, and Chou-Long Huang
Am J Physiol Renal Physiol. 2008; 294:F1212-F1221.  [Abstract] [Full Text] [PDF]

Spike Timing-Dependent Long-Term Potentiation in Ventral Tegmental Area Dopamine Cells Requires PKC
Percy Luu and Robert C Malenka
J Neurophysiol. published 30 April 2008, 10.1152/jn.01384.2007  [Abstract] [PDF]

The angiotensin receptor type 1–Gq protein–phosphatidyl inositol phospholipase C¥â–protein kinase C pathway is involved in activation of proximal tubule Na+-ATPase activity by angiotensin(1–7) in pig kidneys
Lucienne S. Lara, Juliana S. Correa, Anouchka B. Lavelle, Anibal G. Lopes, and Celso Caruso-Neves
Exp Physiol. 2008; 93:639-647.  [Abstract] [Full Text] [PDF]

Protein kinase C {delta}mediates neuronal apoptosis in the retinas of diabetic rats via the Akt signaling pathway
Young-Hee Kim, Yoon-Sook Kim, Chang-Hwan Park, In-Yong Chung, Ji-Myong Yoo, Jae-Geun Kim, Byung-Ju Lee, Sang-Soo Kang, Gyeong-Jae Cho, and Wan-Sung Choi
Diabetes. published 28 April 2008, 10.2337/db07-1431  [Abstract] [PDF]

Loss of ischaemic pre-conditioning in ovariectomized rat hearts: possible involvement of impaired protein kinase C {varepsilon}phosphorylation
Ken Shinmura, Maiko Nagai, Kayoko Tamaki, and Roberto Bolli
Cardiovasc Res. published 25 April 2008, 10.1093/cvr/cvn086  [Abstract] [Full Text] [PDF]

Pulmonary hyperplasia and the two sides of PKC{zeta}
Kristof Graf
Cardiovasc Res. published 24 April 2008, 10.1093/cvr/cvn089  [Extract] [Full Text] [PDF]

Natural killer cells from protein kinase C {theta}–/– mice stimulated with interleukin-12 are deficient in production of interferon-{gamma}
Karen M. Page, Divya Chaudhary, Samuel J. Goldman, and Marion T. Kasaian
J. Leukoc. Biol. 2008; 83:1267-1276.  [Abstract] [Full Text] [PDF]

Protein Kinase C{zeta}-dependent LKB1 Serine 428 Phosphorylation Increases LKB1 Nucleus Export and Apoptosis in Endothelial Cells
Ping Song, Zhonglin Xie, Yong Wu, Jian Xu, Yunzhou Dong, and Ming-Hui Zou
J. Biol. Chem. 2008; 283:12446-12455.  [Abstract] [Full Text] [PDF]