April 2008
Effects
of protein kinase C modulation by PEP005, a novel ingenol angelate, on
mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling in
cancer cells.
M Serova, A Ghoul, KA Benhadji, S Faivre, C Le Tourneau, E Cvitkovic, F Lokiec,
J Lord, SM Ogbourne, F Calvo, and E Raymond
Mol Cancer Ther. 2008; 7:
915. [MEDLINE
Citation]
Pharmacological
Inhibition of {epsilon}-Protein Kinase C Attenuates Cardiac Fibrosis and
Dysfunction in Hypertension-Induced Heart Failure.
Koichi Inagaki, Tomoyoshi Koyanagi, Natalia C Berry, Lihan Sun, and Daria
Mochly-Rosen
Hypertension. 2008. [MEDLINE
Citation]
Down-regulation
of caspase-2 by rottlerin via protein kinase C-delta-independent pathway.
A Basu, B Adkins, and C Basu
Cancer Res. 2008; 68: 2795. [MEDLINE
Citation]
Protein
kinase C isozymes as potential therapeutic targets in immune disorders.
MR Lee, W Duan, and SL Tan
Expert Opin Ther Targets.
2008; 12: 535. [MEDLINE
Citation]
Protein
kinase C in the pancreatic acinar cell.
F Gorelick, S Pandol, and E Thrower
J Gastroenterol Hepatol.
2008; 23 Suppl 1: S37. [MEDLINE
Citation]
Protein
Kinase C and Exocytosis in Mammalian Spermatozoa.
Eduardo R S Roldan and Lynn R Fraser
Trends Endocrinol Metab.
1998; 9: 296. [MEDLINE
Citation]
Protein
kinase C and exocytosis in Mammalian spermatozoa.
Z Naor and H Breitbart
Trends Endocrinol Metab.
1998; 9: 297. [MEDLINE
Citation]
Protein
kinase C and Mammalian spermatozoa acrosome reaction.
Z Naor and H Breitbart
Trends Endocrinol Metab.
1997; 8: 337. [MEDLINE
Citation]
Lack
of evidence for direct phosphorylation of recombinantly expressed P2X(2) and
P2X (3) receptors by protein kinase C.
C Franklin, U Braam, T Eisele, G Schmalzing, and R Hausmann
Purinergic Signal. 2007; 3:
377. [MEDLINE Citation]
Protein
Kinase C-{theta} Critically Regulates the Proliferation and Survival of
Pathogen-Specific T Cells in Murine Listeriosis.
M Sakowicz-Burkiewicz, G Nishanth, U Helmuth, K Drogemuller, DH Busch, O
Utermohlen, M Naumann, M Deckert, and D Schluter
J Immunol. 2008; 180:
5601. [MEDLINE Citation]
THE
NOVEL PROTEIN KINASE C ISOFORMS -{delta} AND -{epsilon} MODULATE
CAERULEIN-INDUCED ZYMOGEN ACTIVATION IN PANCREATIC ACINAR CELLS.
Edwin C Thrower, Sara Osgood, Christine A Shugrue, Thomas R Kolodecik, Anamika
M Chaudhuri, Joseph R Reeve Jr, Stephen J Pandol, and Fred S Gorelick
Am J Physiol Gastrointest Liver Physiol.
2008. [MEDLINE Citation]
ZSET1446
(ST101) treatment rescues olfactory bulbectomy-induced memory impairment by
activating CaM kinase II and protein kinase C in mouse hippocampus.
Feng Han, Norifumi Shioda, Shigeki Moriguchi, Yui Yamamoto, Alisa Ali Raie,
Yoshimasa Yamaguchi, Masataka Hino, and Kohji Fukunaga
J Pharmacol Exp Ther.
2008. [MEDLINE Citation]
Protein
kinase C in the pancreatic acinar cell.
F Gorelick, S Pandol, and E Thrower
J Gastroenterol Hepatol.
2008; 23 Suppl 1: S37. [MEDLINE
Citation]
Inhibition
of Protein Kinase c-Src as a Therapeutic Approach for Cancer and Bone
Metastases.
N Rucci, M Susa, and A Teti
Anticancer Agents Med Chem.
2008; 8: 342. [MEDLINE
Citation]
Loss
of Ischemic Preconditioning in Ovariectomized Rat Hearts: Possible Involvement
of Impaired PKC{varepsilon} Phosphorylation.
Ken Shinmura, Maiko Nagai, Kayoko Tamaki, and Roberto Bolli
Cardiovasc Res. 2008. [MEDLINE
Citation]
Pulmonary
Hyperplasia and the two sides of PKC{zeta}
Kristof Graf
Cardiovasc Res. 2008. [MEDLINE
Citation]
Fluid-flow
induces mechanosensitive ATP release, calcium signalling, and Cl- transport in
biliary epithelial cells through a PKC{zeta}-dependent pathway.
Kangmee Woo, Amal K Dutta, Vishal Patel, Charles Kresge, and Andrew P Feranchak
J Physiol. 2008. [MEDLINE
Citation]
Various
Molecular Species of Diacylglycerol Hydroperoxide Activate Human Neutrophils
via PKC Activation.
Y Kambayashi, S Takekoshi, Y Tanino, K Watanabe, M Nakano, Y Hitomi, T
Takigawa, K Ogino, and Y Yamamoto
J Clin Biochem Nutr. 2007;
41: 68. [MEDLINE Citation]
ZSET1446
(ST101) treatment rescues olfactory bulbectomy-induced memory impairment by
activating CaM kinase II and protein kinase C in mouse hippocampus.
Feng Han, Norifumi Shioda, Shigeki Moriguchi, Yui Yamamoto, Alisa Ali Raie,
Yoshimasa Yamaguchi, Masataka Hino, and Kohji Fukunaga
J Pharmacol Exp Ther.
2008. [MEDLINE Citation]
PMA-dependent
PKCdelta -Y311 phosphorylation in cardiomyocyte caveolae.
Vitalyi O Rybin, Jianfen Guo, Zoya Gertsberg, Steven J Feinmark, and Susan F
Steinberg
J Biol Chem. 2008. [MEDLINE
Citation]
Protein
kinase C 
promotes angiogenic
activity of human endothelial cells via induction of vascular endothelial
growth factor
Hui Xu, Petra Czerwinski, Marcus Hortmann, Hae-Young Sohn, Ulrich Förstermann,
and Huige Li
Cardiovasc Res. 2008;
78:349-355. [Abstract] [Full Text] [PDF]
Protein
kinase C epsilon translocates to the Receptor for Activated C-Kinase upon
adenosine A1 receptor stimulation of the rat myocardium
James G. Dobson, Jr., Lynne G. Shea, Satoshi Komatsu, Mitsuo Ikebe, and Richard
A. Fenton
FASEB J. 2008;
22:748.5.
Protein
Kinase C-dependent Manganese Superoxide Dismutase (MnSOD) Regulation in A549
cells
Youn Wook Chung, Moon Bin Yim, and P. Boon Chock
FASEB J. 2008;
22:645.10.
Protein
kinase C 
-dependent LKB1 phosphorylation at serine 428 induces LKB1 nuclear
export and apoptosis in endothelial cells
Ping Song, Zhonglin Xie, Yong Wu, Jian Xu, Yunzhou Dong, and Ming-Hui Zou
FASEB J. 2008;
22:648.12.
Protein
Kinase C Activity and Cell Proliferation in Polycystic Kidney Disease
Jennifer von der Heiden, Brian Siroky, Monika Gooz, Peter Komlosi, and Phillip
Darwin Bell
FASEB J. 2008;
22:1177.4.
Autophosphorylation
of Protein Kinase C Facilitates its Ubiquitination and Down-regulation
Christine Gould and Alexandra Newton
FASEB J. 2008;
22:1048.4.
Activation
of protein kinase C disrupts epithelial apical junctions via ROCK-dependent
stimulation of myosin II contractility
Andrei I Ivanov, Stanislav N Samarin, Moshe Bachar, Charles A Parkos, and Asma
Nusrat
FASEB J. 2008;
22:464.6.
Effect
of Protein Kinase C inhibitor on angiogenesis in diabetic mice
Reiko Kenmochi, Shonosuke Matsushita, Haruhiko Sugimori, Fujio Sato, and Yuzuru
Sakakibara
FASEB J. 2008;
22:746.13.
Calcium-dependent
protein kinase C alpha and the frequency-dependent increase in phosphorylation
of troponin I in failing hearts
Regis R. Lamberts, Nazha Hamdani, Lori A. Walker, Pieter P. de Tombe, Jolanda
van der Velden, and Ger J. M. Stienen
FASEB J. 2008;
22:751.14.
Role
of protein kinase C (PKC) 
in angiotensin II induced collagen expression in cardiac
myofibroblasts
Laxmansa C Katwa and Vishnu Chintalgattu
FASEB J. 2008;
22:1155.22.
The
role of PKC 
in
T cell development and activation
Guo Fu, Nathalie Niederberger, and Nicholas RJ Gascoigne
FASEB J. 2008;
22:661.12.
Imaging
PKC activity at MAGUK protein scaffolds
Lisa L Gallegos, Erin Garcia, Randy Hall, and Alexandra C Newton
FASEB J. 2008;
22:1048.9.
A
critical role for PKC-theta-mediated T cell survival in cardiac allograft
rejection
Zuoming Sun, Santhkumar Manicassamy, Dengping Yin, Luciana L Molinero, and
Marisa-Luisa Alegre Alegre
FASEB J. 2008;
22:662.8.
The
mechanisms related to the cardioprotective effects of protein kinase C epsilon
(PKC 
-) peptide
inhibitor in ischemia/reperfusion (I/R) injury when given at reperfusion
Qian Chen, Helen Young Kay, Jane Teng, Samantha Burkhart, Christopher Zambrano,
Samuel Krass, Jovan Adams, Christopher Grilli, Giuseppe Guglielmello, Richard
Brue, and Lindon Howard Young
FASEB J. 2008;
22:730.27.
ISOFORM-SPECIFIC
SUBCELLULAR DISTRIBUTION AND ACTIVATION OF PKC MODULATE ENDOTHELIAL BARRIER
INTEGRITY
Nathalie Gaudreault, Rachel M Perrin, Michael Guo, Chase Clanton, Mack H Wu,
and Sarah Y Yuan
FASEB J. 2008;
22:964.14.
PKC
and PKA inhibitors reverse acute tolerance to low- and moderate- but not
high-efficacy mu-opioid agonists
Lynn C Hull, Bichoy H. Gabra, Forrest L. Smith, and William L. Dewey
FASEB J. 2008;
22:1125.9.
Evidence
of calpain and PKC cosignaling in diabetic endothelial dysfunction
Amanda R Smolock and Rosario Scalia
FASEB J. 2008;
22:1128.11.
Integrin-Fibronectin
(FN) Mediated Mechanotransduction of Microvascular Smooth Muscle Cells (VSMC)
Involves Activation of RhoA and PKC-
Zhe Sun, Shaoxing Huang, and Gerald A. Meininger
FASEB J. 2008;
22:744.18.
Role
of protein kinase C (PKC) in angiotensin II induced collagen expression in cardiac myofibroblasts
Laxmansa C Katwa and Vishnu Chintalgattu
FASEB J. 2008;
22:1155.22.
The
expression of cofilin-1 via PKC pathway induced by hyperglycemia in endothelial
cells
Yongming Liu, Yinfang Wang, Fengjie Wang, Juan Deng, Dehong Wu, Hui Su, Yemin
Zhang, Nian Wang, Deling Zhang, and Jingping Ouyang
FASEB J. 2008;
22:964.11.
Protein
Kinase C-
Critically Regulates the Proliferation and Survival of
Pathogen-Specific T Cells in Murine Listeriosis
Monika Sakowicz-Burkiewicz, Gopala Nishanth, Ulrike Helmuth, Katrin
Drögemüller, Dirk H. Busch, Olaf Utermöhlen, Michael Naumann, Martina Deckert,
and Dirk Schlüter
J. Immunol. 2008;
180:5601-5612. [Abstract] [Full Text] [PDF]
A
direct redox regulation of protein kinae C isoenzymes mediates oxidant-induced
neuritogenesis in PC12 cells.
Rayudu Gopalakrishna, Usha Gundimeda, Jason Eric Schiffman, and Thomas H
McNeill
J Biol Chem. 2008. [MEDLINE Citation]
Protein
kinase C alpha modulates liver X receptor alpha transactivation.
CJ Delvecchio and JP Capone
J Endocrinol. 2008; 197:
121. [MEDLINE Citation]
Phosphatidylinositol-3-kinase-atypical
protein kinase C signaling is required for Wnt attraction and
anterior-posterior axon guidance.
AM Wolf, AI Lyuksyutova, AG Fenstermaker, B Shafer, CG Lo, and Y Zou
J Neurosci. 2008; 28:
3456. [MEDLINE Citation]
THE NOVEL
PROTEIN KINASE C ISOFORMS -
AND -
MODULATE CAERULEIN-INDUCED ZYMOGEN ACTIVATION IN
PANCREATIC ACINAR CELLS
Edwin C Thrower, Sara Osgood, Christine A. Shugrue, Thomas R. Kolodecik,
Anamika M. Chaudhuri, Joseph R. Reeve, Jr., Stephen J. Pandol, and Fred S.
Gorelick
Am J Physiol
Gastrointest Liver Physiol.
published 3 April 2008, 10.1152/ajpgi.00020.2008 [Abstract] [PDF]
ZSET1446
(ST101) treatment rescues olfactory bulbectomy-induced memory impairment by
activating CaM kinase II and protein kinase C in mouse hippocampus
Feng Han, Norifumi Shioda, Shigeki Moriguchi, Yui Yamamoto, Alisa Ali Raie,
Yoshimasa Yamaguchi, Masataka Hino, and Kohji Fukunaga
J. Pharmacol. Exp. Ther. published 3 April 2008,
10.1124/jpet.108.137471 [Abstract] [PDF]
PKC¥â
modulates ischemia-reperfusion injury in the heart
Linghua Kong, Martin Andrassy, Jong Sun Chang, Chun Huang, Tomohiro Asai,
Matthias J. Szabolcs, Shunichi Homma, Rui Liu, Yu Shan Zou, Michael Leitges,
Shi Du Yan, Ravichandran Ramasamy, Ann Marie Schmidt, and Shi-Fang Yan
Am J Physiol Heart Circ Physiol.
2008; 294:H1862-H1870. [Abstract] [Full Text] [PDF]
Differential
regulation of Moraxella catarrhalis-induced interleukin-8 response by
protein kinase C isoforms
H. Slevogt, L. Maqami, K. Vardarowa, W. Beermann, A. C. Hocke, J. Eitel, B.
Schmeck, A. Weimann, B. Opitz, S. Hippenstiel, N. Suttorp, and P. D. N'Guessan
Eur. Respir. J. 2008;
31:725-735. [Abstract] [Full Text] [PDF]
Differential
regulation of Moraxella catarrhalis-induced interleukin-8 response by
protein kinase C isoforms
H. Slevogt, L. Maqami, K. Vardarowa, W. Beermann, A. C. Hocke, J. Eitel, B.
Schmeck, A. Weimann, B. Opitz, S. Hippenstiel, N. Suttorp, and P. D. N'Guessan
Eur. Respir. J. 2008;
31:725-735. [Abstract] [Full Text] [PDF]