December 2007

The phosphatase PHLPP controls the cellular levels of protein kinase C
Tianyan Gao, John Brognard, and Alexandra C. Newton
published 27 December 2007, 10.1074/jbc.M707319200  [Abstract] [PDF]

S-phase-specific activation of PKCalpha induces senescence in non-small cell lung cancer cells
Jose Luis Oliva, M. Cecilia Caino, Adrian M. Senderowicz, and Marcelo G. Kazanietz
published 26 December 2007, 10.1074/jbc.M707576200  [Abstract] [PDF]

Eucapnic Intermittent Hypoxia Augments Endothelin-1 Vasoconstriction in Rats: role of PKC{delta}
Kyan J Allahdadi, Laura C Duling, Benjimen R Walker, and Nancy L Kanagy
Am J Physiol Heart Circ Physiol. 2007. [MEDLINE Citation]

PKC-theta activation induces insulin-mediated constriction of muscle resistance arteries.
Wineke Bakker, Pieter Sipkema, Coen D A Stehouwer, Erik H Serne, Yvo M Smulders, Victor W M van Hinsbergh, and Etto C Eringa
Diabetes. 2007. [MEDLINE Citation]

Phosphorylation at S365 is a gatekeeper event that changes the structure of Cx43 and prevents down-regulation by PKC.
JL Solan, L Marquez-Rosado, PL Sorgen, PJ Thornton, PR Gafken, and PD Lampe
J Cell Biol. 2007; 179: 1301. [MEDLINE Citation]

Breviscapine alleviates hepatic injury and inhibits PKC-mRNA and its protein expression in brain-dead BA-Ma mini pigs.
SJ Zhang, Y Song, WL Zhai, JH Shi, LS Feng, YF Zhao, and S Chen
Hepatobiliary Pancreat Dis Int. 2007; 6: 604. [MEDLINE Citation]

Stretch Induction of Cyclooxygenase-2 Expression in Human Urothelial Cells Is Calcium- and Protein Kinase C {zeta}-Dependent.
TJ Jerde, WS Mellon, DE Bjorling, CM Checura, K Owusu-Ofori, JJ Parrish, and SY Nakada
Mol Pharmacol. 2008; 73: 18. [MEDLINE Citation]

Activation of bone morphogenetic protein signaling by a Gemini vitamin D3 analogue is mediated by Ras/protein kinase C alpha.
HJ Lee, Y Ji, S Paul, H Maehr, M Uskokovic, and N Suh
Cancer Res. 2007; 67: 11840. [MEDLINE Citation]

Phorbol ester up-regulates phospholipase D1 but not phospholipase D2 expression through a PKC/ras/ERK/NFkappaB-dependent pathway and enhances matrix metalloproteinase-9 secretion in colon cancer cells
Dong Woo Kang, Mi Hee Park, Young Jun Lee, Hyung Sik Kim, Taeg Kyu Kwon, Won-Sang Park, and Do Sik Min
published 15 December 2007, 10.1074/jbc.M707416200  [Abstract] [PDF]

Stretch Induction of Cyclooxygenase-2 Expression in Human Urothelial Cells Is Calcium- and Protein Kinase C zeta -Dependent

Travis J. Jerde, William S. Mellon, Dale E. Bjorling, Celina M. Checura, Kwadwo Owusu-Ofori, John J. Parrish, and Stephen Y. Nakada (1 January 2008)
Mol. Pharmacol. 73 (1), 18. [DOI: 10.1124/mol.108.035519]
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Bone Morphogenetic Protein Signaling by a Gemini Vitamin D₃ Analogue Is Mediated by Ras/Protein Kinase C alpha
Hong Jin Lee, Yan Ji, Shiby Paul, Hubert Maehr, Milan Uskokovic, and Nanjoo Suh
Cancer Res. 2007; 67:11840-11847.  [Abstract] [Full Text] [PDF]

RACK1, a PKC Targeting Protein, Is Exclusively Localized to Basal Airway Epithelial Cells

Rebecca E. Slager, Jane M. DeVasure, Jaqueline A. Pavlik, Joseph H. Sisson, and Todd A. Wyatt (1 January 2008)
J. Histochem. Cytochem. 56 (1), 7. [DOI: 10.1369/jhc.7A7249.2007]
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation at S365 is a gatekeeper event that changes the structure of Cx43 and prevents down-regulation by PKC
Joell L. Solan, Lucrecia Marquez-Rosado, Paul L. Sorgen, Perry J. Thornton, Philip R. Gafken, and Paul D. Lampe
J. Cell Biol. 2007; 179:1301-1309.  [Abstract] [Full Text] [PDF]

Stromal cell-derived factor 1-{alpha} (SDF)-induced human T cell chemotaxis becomes phosphoinositide 3-kinase (PI3K)-independent: role of PKC-{theta}
Nahid A Shahabi, K McAllen, and Burt M Sharp
J Leukoc Biol. 2007. [MEDLINE Citation]

Protein kinase C {alpha} promotes angiogenic activity of human endothelial cells via induction of vascular endothelial growth factor.
Hui Xu, Petra Czerwinski, Marcus Hortmann, Hae-Young Sohn, Ulrich Forstermann, and Huige Li
Cardiovasc Res. 2007. [MEDLINE Citation]

PKC inhibition and diabetic microvascular complications.
M Clarke and PM Dodson
Best Pract Res Clin Endocrinol Metab. 2007; 21: 573. [MEDLINE Citation]

Protein Kinase C{delta} Regulates Airway Mucin Secretion via Phosphorylation of MARCKS Protein.
JA Park, AL Crews, WR Lampe, S Fang, J Park, and KB Adler
Am J Pathol. 2007; 171: 1822. [MEDLINE Citation]

A triterpene saponin from Tribulus terrestris attenuates apoptosis in cardiocyte via activating PKC signalling transduction pathway.
W Sun, H Li, and SJ Yang
J Asian Nat Prod Res. 2008; 10: 39. [MEDLINE Citation]

Increase in Nitric Oxide and Reductions in Blood Pressure, Protein Kinase C beta II and Oxidative Stress by L-Carnitine: A Study in the Fructose-Fed Hypertensive Rat.
P Rajasekar, N Palanisamy, and CV Anuradha
Clin Exp Hypertens. 2007; 29: 517. [MEDLINE Citation]

Role of protein kinase C-delta in the age-dependent secretagogue action of bile acids in mammalian colon

Jainuch Kanchanapoo, Mei Ao, Roli Prasad, Christopher Moore, Cynthia Kay, Pawinee Piyachaturawat, and Mrinalini C. Rao (1 December 2007)
Am J Physiol Cell Physiol 293 (6), C1851. [DOI: 10.1152/ajpcell.00194.2007]
 |  Abstract »  |  Full Text »  |  PDF »

Phorbol ester stimulation of RasGRP1 regulates the sodium-chloride cotransporter by a PKC-independent pathway
Benjamin Ko, Leena M. Joshi, Leslie L. Cooke, Norma Vazquez, Mark W. Musch, Steven C. Hebert, Gerardo Gamba, and Robert S. Hoover
published 5 December 2007, 10.1073/pnas.0709506104  [Abstract] [PDF]

A structural basis for enhancement of long-term associative memory in single dendritic spines regulated by PKC
Jarin Hongpaisan and Daniel L. Alkon
Proc. Natl. Acad. Sci. USA. 2007; 104:19571-19576. [Abstract] [Full Text] [PDF]

Acrolein Induces Heme Oxygenase-1 Through PKC-{delta} and PI3K in Human Bronchial Epithelial Cells.
Hongqiao Zhang and Henry Jay Forman
Am J Respir Cell Mol Biol. 2007. [MEDLINE Citation]

Immunogold Electron Microscopic Demonstration of Distinct Submembranous Localization of the Activated {gamma}PKC Depending on the Stimulation.
Miho Oyasu, Mineko Fujimiya, Kaori Kashiwagi, Shiho Ohmori, Hirotsugu Imaeda, and Naoaki Saito
J Histochem Cytochem. 2007. [MEDLINE Citation]

A short motif in Kir6.1 consisting of 4 phosphorylation repeats underlies the vascular KATP channel inhibition by protein kinase C.
Yun Shi, Ningren Cui, Weiwei Shi, and Chun Jiang
J Biol Chem. 2007. [MEDLINE Citation]

Modulation of LPS stimulated NF-kappaB mediated Nitric Oxide production by PKC-epsilon and JAK2 in RAW macrophages.
Edward Jones, Ian M Adcock, Bushra Y Ahmed, and Neville A Punchard
J Inflamm (Lond). 2007; 4: 23. [MEDLINE Citation]

Involvement of protein kinase Czeta in interleukin-1beta induction of ADAMTS-4 and type 2 nitric oxide synthase via NF-kappaB signaling in primary human osteoarthritic chondrocytes.
Priya S Chockalingam, Usha Varadarajan, Richard Sheldon, Eric Fortier, Edward R Lavallie, Elisabeth A Morris, Paul J Yaworsky, and Manas K Majumdar
Arthritis Rheum. 2007; 56: 4074. [MEDLINE Citation]

A short motif in Kir6.1 consisting of 4 phosphorylation repeats underlies the vascular KATP channel inhibition by protein kinase C
Yun Shi, Ningren Cui, Weiwei Shi, and Chun Jiang
published 29 November 2007, 10.1074/jbc.M708769200  [Abstract] [PDF]