August 2007

N-Benzyladriamycin-14-valerate (AD 198): A non-cardiotoxic anthracycline that is cardioprotective through PKC-{epsilon} activation.
Polly A Hofmann, Mervyn Israel, Yoshihiro Koseki, Jeffrey Laskin, Joshua Gray, Aleksandra Janik, Trevor W Sweatman, and Leonard Lothstein
J Pharmacol Exp Ther. 2007. [MEDLINE Citation]

Direct PKC-dependent phosphorylation regulates the cell surface stability and activity of the potassium chloride cotransporter, KCC2.
Henry H C Lee, Joshua A Walker, Jeffery R Williams, Richard R Goodier, John A Payne, and Stephen J Moss
J Biol Chem. 2007.
 [MEDLINE Citation]

Role of PKC{zeta} and its adaptor protein p62 in KV channel modulation in pulmonary arteries.
Laura Moreno, Giovanna Frazziano, Angel Cogolludo, Laura Cobeno, Juan Tamargo, and Francisco Perez-Vizcaino
Mol Pharmacol.
2007. [MEDLINE Citation]

A critical role of Epac in switching protein kinase signaling in PGE2-induced potentiation of P2X3 receptor currents in inflamed rats.
Congying Wang, Yanping Gu, Guang-Wen Li, and Li-Yen M Huang
J Physiol. 2007. [MEDLINE Citation]

Protein kinase C regulates local synthesis and secretion of a neuropeptide required for activity-dependent long-term synaptic plasticity.
JY Hu, Y Chen, and S Schacher
J Neurosci.
2007; 27: 8927. [MEDLINE Citation]

Essential role for Rap1 GTPase and its guanine exchange factor CalDAG-GEFI in LFA-1 but not VLA-4 integrin-mediated human T cell adhesion.
Haifa Ghandour, Xavier Cullere, Francis W Luscinskas, and Tanya N Mayadas
Blood.
2007. [MEDLINE Citation]

Alpha-2 Noradrenergic Receptor Activation Enhances Excitability and Synaptic Integration in Prefrontal Cortex Pyramidal Neurons via Inhibition of HCN Currents.
David B Carr, Glenn D Andrews, William B Glen, and Antonieta Lavin
J Physiol. 2007.
 [MEDLINE Citation]

C-TYPE NATRIURETIC PEPTIDE ENHANCES AMYLASE RELEASE THROUGH NPR-C RECEPTORS IN THE EXOCRINE PANCREAS.
Maria Eugenia Sabbatini, Myrian Roxana Rodriguez, Maria Beatriz di Carlo, Carlos Alberto Davio, Marcelo Sergio Vatta, and Liliana G Bianciotti
Am J Physiol Gastrointest Liver Physiol. 2007. [MEDLINE Citation]

The Role of Glycogen Synthase Kinase 3{beta} in the Transformation of Epidermal Cells.
C Ma, J Wang, Y Gao, TW Gao, G Chen, KA Bower, M Odetallah, M Ding, Z Ke, and J Luo
Cancer Res. 2007; 67: 7756. [MEDLINE Citation]

A Novel Role for Protein Kinase C{delta}-Mediated Phosphorylation of Acid Sphingomyelinase in UV Light-Induced Mitochondrial Injury.
Youssef H Zeidan, Bill X Wu, Russell W Jenkins, Lina M Obeid, and Yusuf A Hannun
FASEB J. 2007.
 [MEDLINE Citation]

{alpha}- and {epsilon}-Protein Kinase C Activity during Smooth Muscle Cell Apoptosis in Response to {gamma}-Radiation

Sandra Claro, Celia Akemi Kanashiro, Maria Etsuko Miyamoto Oshiro, Alice Teixeira Ferreira, and Raouf Ali Khalil (1 September 2007)
J. Pharmacol. Exp. Ther. 322 (3), 964. [DOI: 10.1124/jpet.107.125930]
 |  Abstract »  |  Full Text »  |  PDF »
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Neuroprotective Effect of Protein Kinase C{delta} Inhibitor Rottlerin in Cell Culture and Animal Models of Parkinson's Disease

Danhui Zhang, Vellareddy Anantharam, Arthi Kanthasamy, and Anumantha G. Kanthasamy (1 September 2007)
J. Pharmacol. Exp. Ther. 322 (3), 913. [DOI: 10.1124/jpet.107.124669]
 |  Abstract »  |  Full Text »  |  PDF »
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Regulation of {alpha}1-Adrenoceptor-Mediated Contractions of the Uterine Artery by Protein Kinase C: Role of the Thick- and Thin-Filament Regulatory Pathways

Hongying Zhang and Lubo Zhang (1 September 2007)
J. Pharmacol. Exp. Ther. 322 (3), 1253. [DOI: 10.1124/jpet.107.124313]
 |  Abstract »  |  Full Text »  |  PDF »

Direct PKC-dependent phosphorylation regulates the cell surface stability and activity of the potassium chloride cotransporter, KCC2
Henry H. C. Lee, Joshua A. Walker, Jeffery R. Williams, Richard R. Goodier, John A. Payne, and Stephen J. Moss
published 10 August 2007, 10.1074/jbc.M705053200  [Abstract] [PDF]

Cyclical mechanical stretch modulates expression of collagen I and collagen III by PKC and tyrosine kinase in cardiac fibroblasts.
Britta Husse, Wilfried Briest, Lars Homagk, Gerrit Isenberg, and Michael Gekle
Am J Physiol Regul Integr Comp Physiol. 2007. [MEDLINE Citation]

Local Delivery of PKC{epsilon}-Activating Peptide Mimics Ischemic Preconditioning in Aged Hearts Through GSK3{beta} but not F1ATPase Inactivation.
Donna H Korzick, John C Kostyak, James Craig Hunter, and Kurt W Saupe
Am J Physiol Heart Circ Physiol. 2007.
 [MEDLINE Citation]

Protein Kinase C in the Nucleus Tractus Solitarii is critically involved in the acute hypoxic ventilatory response, but is not required for intermittent hypoxia-induced phrenic long-term facilitation in adult rats.
Stephen R Reeves and David Gozal
Exp Physiol. 2007.
 [MEDLINE Citation]

Effects of protein kinase C activation on cardiac repolarization and arrhythmogenesis in Langendorff-perfused rabbit hearts.
Oezguer Aydin, Ruediger Becker, Patricia Kraft, Frederik Voss, Martin Koch, Kamilla Kelemen, Hugo A Katus, and Alexander Bauer
Europace.
2007. [MEDLINE Citation]

PKC-mediated modulation of Factor Inhibiting HIF-1 (FIH-1) expression by the homoedomain protein CDP/Cut/Cux
Jinping Li, Enfeng Wang, Shamit Dutta, Julie S. Lau, Shi-wen Jiang, Kaustubh Datta, and Debabrata Mukhopadhyay
published 6 August 2007, 10.1128/MCB.02201-06  [Abstract] [PDF]

Protein Kinase C{epsilon} (PKC{epsilon}) and Src Control PKC{delta} Activation Loop Phosphorylation in Cardiomyocytes
Vitalyi O. Rybin, Jianfen Guo, Zoya Gertsberg, Hasnae Elouardighi, and Susan F. Steinberg
J. Biol. Chem. 2007; 282:23631-23638.  [Abstract] [Full Text] [PDF]

Identification of acidic amino acid residues in the PKCalpha V5 domain that contribute to its insensitivity to diacylglycerol
Helena Stensman and Christer Larsson
published 2 August 2007, 10.1074/jbc.M702248200  [Abstract] [PDF]

Decrease in PIP2–channel interactions is the final common mechanism involved in PKC- and arachidonic acid-mediated inhibitions of GABAB-activated K+ current

Jong-Woo Sohn, Ajin Lim, Suk-Ho Lee, and Won-Kyung Ho (1 August 2007)
J. Physiol. 582 (3), 1037. [DOI: 10.1113/jphysiol.2007.137265]
 |  Abstract »  |  Full Text »  |  PDF »  |  Supplemental data »
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Vasoconstrictor effect of endothelin-1 on hypertensive pulmonary arterial smooth muscle involves Rho-kinase and protein kinase C

Scott A. Barman (1 August 2007)
Am J Physiol Lung Cell Mol Physiol 293 (2), L472. [DOI: 10.1152/ajplung.00101.2006]
 |  Abstract »  |  Full Text »  |  PDF »
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