|
Substrates |
Year |
Title |
Web link |
|
14-3-3gamma |
1999 |
14-3-3Gamma interacts with and is phosphorylated by multiple protein
kinase C isoforms in PDGF-stimulated human vascular smooth muscle cells. |
http://www.ncbi.nlm.nih.gov/pubmed/10433554 |
|
5-HT2A receptors |
2002 |
Internalization and recycling of 5-HT2A receptors activated by serotonin
and protein kinase C-mediated mechanisms. |
http://www.ncbi.nlm.nih.gov/pubmed/12388782 |
|
Adducin |
1998 |
Adducin is an in vivo substrate for protein kinase C: phosphorylation in
the MARCKS-related domain inhibits activity in promoting spectrin-actin
complexes and occurs in many cells, including dendritic spines of
neurons. |
http://www.ncbi.nlm.nih.gov/pubmed/9679146 |
|
alpha4beta2 nicotinic receptor subunits |
2009 |
Cyclic AMP-dependent protein kinase A and protein kinase C phosphorylate
alpha4beta2 nicotinic receptor subunits at distinct stages of receptor
formation and maturation. |
http://www.ncbi.nlm.nih.gov/pubmed/19101612 |
|
Apoprotein A-1 |
1991 |
Apoprotein A-1 is a cofactor independent substrate of protein kinase C. |
http://www.ncbi.nlm.nih.gov/pubmed/1909124 |
|
Bcl-2 |
2009 |
PKC delta signaling: a dual role in regulating hypoxic stress-induced
autophagy and apoptosis. |
http://www.ncbi.nlm.nih.gov/pubmed/19098423 |
|
CAK |
2002 |
Human glioma PKC-iota and PKC-betaII phosphorylate cyclin-dependent
kinase activating kinase during the cell cycle. |
http://www.ncbi.nlm.nih.gov/pubmed/11856176 |
|
Caldesmon77, Vimentin |
1992 |
Protein kinase C phosphorylates caldesmon77 and vimentin and enhances
albumin permeability across cultured bovine pulmonary artery endothelial
cell monolayers |
http://www.ncbi.nlm.nih.gov/pubmed/1522136 |
|
CaM-kinase |
1993 |
Ca2+/calmodulin-dependent protein kinase II is phosphorylated by protein
kinase C in vitro |
http://www.ncbi.nlm.nih.gov/pubmed/8384482 |
|
Cbl-b |
2009 |
PKC-theta modulates the strength of T cell responses by targeting Cbl-b
for ubiquitination and degradation. |
http://www.ncbi.nlm.nih.gov/pubmed/19549985 |
|
CD34 antigen |
1990 |
Activated protein kinase C directly phosphorylates the CD34 antigen on
hematopoietic cells |
http://www.ncbi.nlm.nih.gov/pubmed/1283964 |
|
CD34 antigen |
1992 |
Activated protein kinase C directly phosphorylates the CD34 antigen in
acute lymphoblastic leukemia cells |
http://www.ncbi.nlm.nih.gov/pubmed/1694174 |
|
CD8 alpha |
1990 |
Murine T-cell differentiation antigen CD8 is a direct substrate of
protein kinase C |
http://www.ncbi.nlm.nih.gov/pubmed/2115328 |
|
Centaurin-alpha(1) |
2003 |
Centaurin-alpha(1) associates with and is phosphorylated by isoforms of
protein kinase C |
http://www.ncbi.nlm.nih.gov/pubmed/12893243 |
|
c-FLIP |
2009 |
PKC-mediated phosphorylation regulates c-FLIP ubiquitylation and
stability. |
http://www.ncbi.nlm.nih.gov/pubmed/19343040 |
|
Choline acetyltransferase (ChAT) |
2004 |
Protein kinase C isoforms differentially phosphorylate human choline
acetyltransferase regulating its catalytic activity |
http://www.ncbi.nlm.nih.gov/pubmed/15381704 |
|
Chromatin-associated proteins |
1992 |
Importance of substrate conformation in the phosphorylation of
chromatin-associated proteins by exogenous protein kinase C. |
http://www.ncbi.nlm.nih.gov/pubmed/1616821 |
|
Clone 72 |
1999 |
Developmental expression of the protein kinase C substrate/binding
protein (clone 72/SSeCKS) in rat testis identification as a scaffolding
protein containing an A-kinase-anchoring domain which is expressed
during late-stage spermatogenesis |
http://www.ncbi.nlm.nih.gov/pubmed/10469144 |
|
CREB |
2009 |
Morphine withdrawal regulates phosphorylation of cAMP response element
binding protein (CREB) through PKC in the nucleus tractus solitarius-A2
catecholaminergic neurons. |
http://www.ncbi.nlm.nih.gov/pubmed/19545278 |
|
CYP3A4 |
2009 |
A Role for Protein Phosphorylation in Cytochrome P450 3A4
Ubiquitin-dependent Proteasomal Degradation |
http://www.ncbi.nlm.nih.gov/pubmed/19095658 |
|
Cytokeratins 8 and18 (CK8, CK18) |
1992 |
PKC epsilon-related kinase associates with and phosphorylates
cytokeratin 8 and 18 |
http://www.ncbi.nlm.nih.gov/pubmed/1374067 |
|
DAG kinase |
1993 |
Diacylglycerol kinase is phosphorylated in vivo upon stimulation of the
epidermal growth factor receptor and serine/threonine kinases, including
protein kinase C-epsilon |
http://www.ncbi.nlm.nih.gov/pubmed/7679574 |
|
DAG kinase (DGK) zeta |
2003 |
Protein kinase C alpha phosphorylates and negatively regulates
diacylglycerol kinase zeta |
http://www.ncbi.nlm.nih.gov/pubmed/12890670 |
|
Deoxyhypusine synthase |
2002 |
Deoxyhypusine synthase is phosphorylated by protein kinase C in vivo as
well as in vitro |
http://www.ncbi.nlm.nih.gov/pubmed/12526092 |
|
DNA topoisomerase I |
1989 |
Protein kinase C phosphorylates DNA topoisomerase I |
http://www.ncbi.nlm.nih.gov/pubmed/2557245 |
|
DNA topoisomerase I |
2003 |
Pea DNA topoisomerase I is phosphorylated and stimulated by casein
kinase 2 and protein kinase C |
http://www.ncbi.nlm.nih.gov/pubmed/12913165 |
|
EBV membrane receptor (CR2) |
1993 |
EBV membrane receptor (CR2) is phosphorylated by protein kinase C (PKC)
in the early stages of virus entry into lymphoblastoid cells line (Raji) |
http://www.ncbi.nlm.nih.gov/pubmed/7694579 |
|
Endothelial nitric oxide synthase |
2009 |
Phosphorylation of endothelial nitric oxide synthase by atypical PKC
zeta contributes to angiopoietin-1-dependent inhibition of VEGF-induced
endothelial permeability in vitro. |
http://www.ncbi.nlm.nih.gov/pubmed/19564638 |
|
eNOS |
2009 |
Homocysteine decreases platelet NO level via protein kinase C activation |
http://www.ncbi.nlm.nih.gov/pubmed/19100855 |
|
EWS |
1997 |
The prooncoprotein EWS binds calmodulin and is phosphorylated by protein
kinase C through an IQ domain |
http://www.ncbi.nlm.nih.gov/pubmed/9341188 |
|
Filamin A |
2003 |
The F-actin cross-linking and focal adhesion protein filamin A is a
ligand and in vivo substrate for protein kinase C alpha |
http://www.ncbi.nlm.nih.gov/pubmed/12704190 |
|
FMIP |
2004 |
The M-CSF receptor substrate and interacting protein FMIP is governed in
its subcellular localization by protein kinase C-mediated
phosphorylation, and thereby potentiates M-CSF-mediated differentiation |
http://www.ncbi.nlm.nih.gov/pubmed/15221008 |
|
FOS |
1991 |
Fos is phosphorylated by p34cdc2, cAMP-dependent protein kinase and
protein kinase C at multiple sites clustered within regulatory regions |
http://www.ncbi.nlm.nih.gov/pubmed/1766667 |
|
GABA(A) receptor beta |
2002 |
Receptor for activated C kinase-1 facilitates protein kinase C-dependent
phosphorylation and functional modulation of GABA(A) receptors with the
activation of G-protein-coupled receptors |
http://www.ncbi.nlm.nih.gov/pubmed/12151513 |
|
GABAA-R |
1993 |
Ca2+/calmodulin-dependent protein kinase II and protein kinase C
phosphorylate a synthetic peptide corresponding to a sequence that is
specific for the gamma 2L subunit of the GABAA receptor |
http://www.ncbi.nlm.nih.gov/pubmed/8390566 |
|
GABAA-R |
1993 |
Phosphorylation of the GABAA receptor by cAMP-dependent protein kinase
and by protein kinase C: analysis of the substrate domain |
http://www.ncbi.nlm.nih.gov/pubmed/8385279 |
|
GAP |
1993 |
Protein kinase C forms a complex with and phosphorylates the GTPase
activating protein GAP: phosphorylation by PKC is dependent on tyrosine
phosphorylation of GAP and/or a GAP-associated protein |
http://www.ncbi.nlm.nih.gov/pubmed/7687440 |
|
GAP-43 |
1995 |
Protein kinase C substrates in corneal epithelium during wound healing:
the phosphorylation of growth associated protein-43 (GAP-43) |
http://www.ncbi.nlm.nih.gov/pubmed/8549686 |
|
GAP-43 |
2009 |
Electroconvulsive seizure increases phosphorylation of PKC substrates,
including GAP-43, MARCKS, and neurogranin, in rat brain. |
http://www.ncbi.nlm.nih.gov/pubmed/19837121 |
|
GBPI |
2004 |
GBPI, a novel gastrointestinal- and brain-specific PP1-inhibitory
protein, is activated by PKC and inactivated by PKA |
http://www.ncbi.nlm.nih.gov/pubmed/12974676 |
|
Glutamate receptor 5a (mGluR5a) |
2004 |
Isoform-specific phosphorylation of metabotropic glutamate receptor 5 by
protein kinase C (PKC) blocks Ca2+ oscillation and oscillatory
translocation of Ca2+-dependent PKC |
http://www.ncbi.nlm.nih.gov/pubmed/14561742 |
|
GMF |
1997 |
Protein kinase A (PKA)- and protein kinase C-phosphorylated glia
maturation factor promotes the catalytic activity of PKA |
http://www.ncbi.nlm.nih.gov/pubmed/9030586 |
|
hASIC1b |
2009 |
Two PKC consensus sites on human acid-sensing ion channel 1b
differentially regulate its function |
http://www.ncbi.nlm.nih.gov/pubmed/19091960 |
|
HCV(1487-1500) |
2000 |
A synthetic peptide derived from the non-structural protein 3 of
hepatitis C virus serves as a specific substrate for PKC |
http://www.ncbi.nlm.nih.gov/pubmed/10722046 |
|
Heat shock protein 25 |
2005 |
HSP25 inhibits protein kinase C delta-mediated cell death through direct
interaction |
http://www.ncbi.nlm.nih.gov/pubmed/15731106 |
|
Heat shock protein 27 |
2007 |
Inhibition of heat shock protein 27-mediated resistance to DNA damaging
agents by a novel PKC delta-V5 heptapeptide |
http://www.ncbi.nlm.nih.gov/pubmed/17616692 |
|
Heat-shock protein-25/28 |
1998 |
Heat-shock protein-25/27 phosphorylation by the delta isoform of protein
kinase C |
http://www.ncbi.nlm.nih.gov/pubmed/9620873 |
|
Hematoxylin-stainable protein (HSP) |
1991 |
Identification of hematoxylin-stainable protein in epidermal
keratohyalin granules as phosphorylated cystatin alpha by protein kinase
C |
http://www.ncbi.nlm.nih.gov/pubmed/1715284 |
|
Heme-modified CYP3A4 |
2001 |
Phosphorylation of native and heme-modified CYP3A4 by protein kinase C:
a mass spectrometric characterization of the phosphorylated peptides. |
http://www.ncbi.nlm.nih.gov/pubmed/11560479 |
|
Hepatitis B virus-X protein |
2001 |
Phosphorylation of purified recombinant hepatitis B virus-X protein by
mitogen-activated protein kinase and protein kinase C in vitro. |
http://www.ncbi.nlm.nih.gov/pubmed/11377708 |
|
hnRNPA1 |
1995 |
Identification of heterogeneous ribonucleoprotein A1 as a novel
substrate for protein kinase C zeta |
http://www.ncbi.nlm.nih.gov/pubmed/7541049 |
|
IP(3)R |
2004 |
Regulation of the phosphorylation of the inositol 1,4,5-trisphosphate
receptor by protein kinase C |
http://www.ncbi.nlm.nih.gov/pubmed/15184066 |
|
IRAK |
2004 |
Regulation of interleukin receptor-associated kinase (IRAK)
phosphorylation and signaling by iota protein kinase C |
http://www.ncbi.nlm.nih.gov/pubmed/14684752 |
|
IRAP |
2002 |
Protein kinase C-zeta phosphorylates insulin-responsive aminopeptidase
in vitro at Ser-80 and Ser-91 |
http://www.ncbi.nlm.nih.gov/pubmed/12061804 |
|
IRS-1 |
2001 |
Protein kinase C-zeta phosphorylates insulin receptor substrate-1 and
impairs its ability to activate phosphatidylinositol 3-kinase in
response to insulin. |
http://www.ncbi.nlm.nih.gov/pubmed/11063744 |
|
IRS-1 |
2004 |
In vitro phosphorylation of insulin receptor substrate 1 by protein
kinase C-zeta: functional analysis and identification of novel
phosphorylation sites |
http://www.ncbi.nlm.nih.gov/pubmed/15134463 |
|
IRS-1 |
2004 |
Protein kinase C (PKC) beta modulates serine phosphorylation of insulin
receptor substrate-1 (IRS-1)--effect of overexpression of PKCbeta on
insulin signal transduction |
http://www.ncbi.nlm.nih.gov/pubmed/15473137 |
|
IRS-1 |
2004 |
Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin
receptor substrate-1 (IRS-1) attenuates the interaction with the insulin
receptor and the tyrosine phosphorylation of IRS-1 |
http://www.ncbi.nlm.nih.gov/pubmed/15069075 |
|
IRS-1 |
2004 |
Modulation of human insulin receptor substrate-1 tyrosine
phosphorylation by protein kinase Cdelta |
http://www.ncbi.nlm.nih.gov/pubmed/14583092 |
|
JAM |
2000 |
Junctional adhesion molecule (JAM) is phosphorylated by protein kinase C
upon platelet activation |
http://www.ncbi.nlm.nih.gov/pubmed/11027562 |
|
KCIP-1 |
1992 |
Multiple isoforms of a protein kinase C inhibitor (KCIP-1/14-3-3) from
sheep brain. Amino acid sequence of phosphorylated forms |
http://www.ncbi.nlm.nih.gov/pubmed/1317796 |
|
KIBRA |
2004 |
KIBRA is a novel substrate for protein kinase Czeta |
http://www.ncbi.nlm.nih.gov/pubmed/15081397 |
|
KP-10 |
1994 |
KP-10, a novel protein kinase C substrate in intact mouse epidermal
cells, is phosphorylated by novel protein kinase C eta and/or zeta |
http://www.ncbi.nlm.nih.gov/pubmed/7818986 |
|
LAT |
2003 |
Modulation of the electrophoretic mobility of the linker for activation
of T cells (LAT) by the calcineurin inhibitors CsA and FK506: LAT is a
potential substrate for PKC and calcineurin signaling pathways |
http://www.ncbi.nlm.nih.gov/pubmed/12401523 |
|
Lipocortins |
1990 |
Lipocortins are major substrates for protein kinase C in extracts of
human neutrophils |
http://www.ncbi.nlm.nih.gov/pubmed/1692066 |
|
MacMARCKS |
1992 |
MacMARCKS, a novel member of the MARCKS family of protein kinase C
substrates |
http://www.ncbi.nlm.nih.gov/pubmed/1516135 |
|
MacMARCKS |
2000 |
Protein kinase C-regulated dynamitin-macrophage-enriched myristoylated
alanine-rice C kinase substrate interaction is involved in macrophage
cell spreading |
http://www.ncbi.nlm.nih.gov/pubmed/10827182 |
|
MAPK |
1993 |
PKC-mediated redistribution of mitogen-activated protein kinase during
smooth muscle cell activation |
http://www.ncbi.nlm.nih.gov/pubmed/8368270 |
|
MAPK |
1994 |
Regulation of mitogen-activated protein kinase activation by protein
kinases A and C in a cell-free system |
http://www.ncbi.nlm.nih.gov/pubmed/7929138 |
|
MAPK |
1995 |
Activation of mitogen-activated protein kinase by arachidonic acid in
rat liver epithelial WB cells by a protein kinase C-dependent mechanism |
http://www.ncbi.nlm.nih.gov/pubmed/7876176 |
|
MAPK |
1995 |
Epidermal growth factor stimulates mitogen-activated protein kinase by a
PKC-dependent pathway in human keratinocytes |
http://www.ncbi.nlm.nih.gov/pubmed/7534073 |
|
MAPK |
1995 |
Overexpression of epsilon-protein kinase C enhances nerve growth
factor-induced phosphorylation of mitogen-activated protein kinases and
neurite outgrowth |
http://www.ncbi.nlm.nih.gov/pubmed/8530420 |
|
MAPK |
1997 |
Activation of mitogen-activated protein kinase in freshly isolated rat
hepatocytes by both a calcium- and a protein kinase C-dependent pathway |
http://www.ncbi.nlm.nih.gov/pubmed/9160823 |
|
MAPK |
1997 |
Antigen activation of mitogen-activated protein kinase in mast cells
through protein kinase C-dependent and independent pathways |
http://www.ncbi.nlm.nih.gov/pubmed/9144516 |
|
MAPK |
1997 |
CGP 41251 and tamoxifen selectively inhibit mitogen-activated protein
kinase activation and c-Fos phosphoprotein induction by substance P in
human astrocytoma cells |
http://www.ncbi.nlm.nih.gov/pubmed/9372245 |
|
MAPK |
1997 |
Growth hormone and phorbol esters require specific protein kinase C
isoforms to activate mitogen-activated protein kinases in 3T3-F442A
cells |
http://www.ncbi.nlm.nih.gov/pubmed/9164852 |
|
MAPK |
1998 |
Bombesin stimulates cholecystokinin secretion through mitogen-activated
protein-kinase-dependent and -independent mechanisms in the
enteroendocrine STC-1 cell line |
http://www.ncbi.nlm.nih.gov/pubmed/9512470 |
|
MAPK |
1998 |
Involvement of tyrosine kinases, Ca2+ and PKC in activation of
mitogen-activated protein (MAP) kinase in human polymorphonuclear
neutrophils |
http://www.ncbi.nlm.nih.gov/pubmed/9806988 |
|
MAPK |
1998 |
Mitogen-activated protein kinase is activated during IgG-mediated
phagocytosis, but is not required for target ingestion |
http://www.ncbi.nlm.nih.gov/pubmed/9484651 |
|
MAPK |
1999 |
Mechanisms of mitogen-activated protein kinase activation in
experimental diabete |
http://www.ncbi.nlm.nih.gov/pubmed/10203357 |
|
MAPK |
2001 |
Respiratory syncytial virus infection results in activation of multiple
protein kinase C isoforms leading to activation of mitogen-activated
protein kinase. |
http://www.ncbi.nlm.nih.gov/pubmed/11160332 |
|
MAPK |
2001 |
Differential activation of mitogen-activated protein kinase cascades and
apoptosis by protein kinase C epsilon and delta in neonatal rat
ventricular myocytes. |
http://www.ncbi.nlm.nih.gov/pubmed/11701615 |
|
MAPK |
2001 |
Glycated serum albumin-induced vascular smooth muscle cell proliferation
through activation of the mitogen-activated protein kinase/extracellular
signal-regulated kinase pathway by protein kinase C. |
http://www.ncbi.nlm.nih.gov/pubmed/11237743 |
|
MAPK |
2001 |
Lovastatin blocks basic fibroblast growth factor-induced
mitogen-activated protein kinase signaling in coronary smooth muscle
cells via phosphatase inhibition |
http://www.ncbi.nlm.nih.gov/pubmed/11322384 |
|
MAPK |
2001 |
Phosphorylation of mitogen-activated protein kinase is regulated by
protein kinase C, cyclic 3',5'-adenosine monophosphate, and protein
phosphatase modulators during meiosis resumption in rat oocytes. |
http://www.ncbi.nlm.nih.gov/pubmed/11319150 |
|
MAPK |
2001 |
Protein kinase C mu selectively activates the mitogen-activated protein
kinase (MAPK) p42 pathway. |
http://www.ncbi.nlm.nih.gov/pubmed/11248233 |
|
MAPK |
2001 |
Stimulation of endothelin B receptors in astrocytes induces cAMP
response element-binding protein phosphorylation and c-fos expression
via multiple mitogen-activated protein kinase signaling pathways |
http://www.ncbi.nlm.nih.gov/pubmed/11698596 |
|
MAPK |
2002 |
Enhancement of anchorage-independent growth of human pancreatic
carcinoma MIA PaCa-2 cells by signaling from protein kinase C to
mitogen-activated protein kinase |
http://www.ncbi.nlm.nih.gov/pubmed/12203369 |
|
MAPK |
2002 |
Novel protein kinase C isoforms and mitogen-activated kinase kinase
mediate phorbol ester-induced osteopontin expression |
http://www.ncbi.nlm.nih.gov/pubmed/12009309 |
|
MAPK |
1995 |
Forskolin inhibits protein kinase C-induced mitogen activated protein
kinase activity in MC3T3-E1 osteoblasts |
http://www.ncbi.nlm.nih.gov/pubmed/7588214 |
|
MAPK |
1996 |
Mitogen-activated protein kinase activation in hepatocyte growth
factor-stimulated rat hepatocytes: involvement of protein tyrosine
kinase and protein kinase C |
http://www.ncbi.nlm.nih.gov/pubmed/8621160 |
|
MARC, (GAP)-43/B-50 |
1999 |
Differential changes in the phosphorylation of the protein kinase C
substrates myristoylated alanine-rich C kinase substrate and
growth-associated protein-43/B-50 following Schaffer collateral
long-term potentiation and long-term depression |
http://www.ncbi.nlm.nih.gov/pubmed/10537078 |
|
MARCKS |
1990 |
Activation of protein kinase C results in the displacement of its
myristoylated, alanine-rich substrate from punctate structures in
macrophage filopodia |
http://www.ncbi.nlm.nih.gov/pubmed/2212950 |
|
MARCKS |
1990 |
Protein kinase C and its 80-kilodalton substrate protein in
neuroblastoma cell neurite outgrowth |
http://www.ncbi.nlm.nih.gov/pubmed/2293618 |
|
MARCKS |
1991 |
Phosphorylation of MARCKS (80-kDa) protein, a major substrate for
protein kinase C in oligodendroglial progenitors |
http://www.ncbi.nlm.nih.gov/pubmed/1798060 |
|
MARCKS |
1991 |
Transformed 3T3 cells have reduced levels and altered subcellular
distribution of the major PKC substrate protein MARCKS |
http://www.ncbi.nlm.nih.gov/pubmed/1838487 |
|
MARCKS |
1992 |
Phosphorylation of the MARCKS protein (P87), a major protein kinase C
substrate, is not an obligatory step in the mitogenic signaling pathway
of basic fibroblast growth factor in rat oligodendrocytes |
http://www.ncbi.nlm.nih.gov/pubmed/1309563 |
|
MARCKS |
1992 |
Relationship between the major protein kinase C substrates acidic 80-kDa
protein-kinase-C substrate (80K) and myristoylated alanine-rich C-kinase
substrate (MARCKS). Members of a gene family or equivalent genes in
different species |
http://www.ncbi.nlm.nih.gov/pubmed/1396720 |
|
MARCKS |
1992 |
The expression of 80K/MARCKS, a major substrate of protein kinase C
(PKC), is down-regulated through both PKC-dependent and -independent
pathways. Effects of bombesin, platelet-derived growth factor, and cAMP |
http://www.ncbi.nlm.nih.gov/pubmed/1378435 |
|
MARCKS |
1992 |
Thrombin and histamine rapidly stimulate the phosphorylation of the
myristoylated alanine-rich C-kinase substrate in human umbilical vein
endothelial cells: evidence for distinct patterns of protein kinase
activation |
http://www.ncbi.nlm.nih.gov/pubmed/1320036 |
|
MARCKS |
1992 |
Transforming growth factor-beta (TGF-b) induced phosphorylation of the
myristoylated alanine rich C kinase substrate (MARCKS) protein in
ovarian granulosa cells is modulated by follicle stimulating hormone
(FSH) |
http://www.ncbi.nlm.nih.gov/pubmed/1335598 |
|
MARCKS |
1993 |
A myristoylated pseudosubstrate peptide, a novel protein kinase C
inhibitor |
http://www.ncbi.nlm.nih.gov/pubmed/8420972 |
|
MARCKS |
1993 |
Brain protein kinase C assay using MARCKS substrate reveals no
translocation due to profound insulin-induced hypoglycemia |
http://www.ncbi.nlm.nih.gov/pubmed/8490715 |
|
MARCKS |
1993 |
Effects of insulin and phorbol esters on MARCKS (myristoylated
alanine-rich C-kinase substrate) phosphorylation (and other parameters
of protein kinase C activation) in rat adipocytes, rat soleus muscle and
BC3H-1 myocytes |
http://www.ncbi.nlm.nih.gov/pubmed/8216211 |
|
MARCKS |
1993 |
Enhancement by protein kinase C of prostacyclin receptor-mediated
activation of adenylate cyclase through a calmodulin/myristoylated
alanine-rich C kinase substrate (MARCKS) system in IC2 mast cells |
http://www.ncbi.nlm.nih.gov/pubmed/8380584 |
|
MARCKS |
1993 |
Expression of the major protein kinase C substrate, the acidic
80-kilodalton myristoylated alanine-rich C kinase substrate, increases
sharply when Swiss 3T3 cells move out of cycle and enter G0 |
http://www.ncbi.nlm.nih.gov/pubmed/8464911 |
|
MARCKS |
1993 |
Protein kinase C phosphorylates Ser152, Ser156 and Ser163 but not Ser160
of MARCKS in rat brain |
http://www.ncbi.nlm.nih.gov/pubmed/8422248 |
|
MARCKS |
1993 |
Whole-cell recording of neuroblastoma x glioma cells during
downregulation of a major substrate, 80K/MARCKS, of protein kinase C |
http://www.ncbi.nlm.nih.gov/pubmed/8320719 |
|
MARCKS |
1994 |
Arginine vasopressin (AVP) causes the reversible phosphorylation of the
myristoylated alanine-rich C kinase substrate (MARCKS) protein in the
ovine anterior pituitary: evidence that MARCKS phosphorylation is
associated with adrenocorticotropin (ACTH) secretion |
http://www.ncbi.nlm.nih.gov/pubmed/9397959 |
|
MARCKS |
1994 |
Glutamate exocytosis and MARCKS phosphorylation are enhanced by a
metabotropic glutamate receptor coupled to a protein kinase C
synergistically activated by diacylglycerol and arachidonic acid |
http://www.ncbi.nlm.nih.gov/pubmed/7931282 |
|
MARCKS |
1994 |
Phorbol ester- and retinoic acid-induced regulation of the protein
kinase C substrate MARCKS in immortalized hippocampal cells |
http://www.ncbi.nlm.nih.gov/pubmed/7931322 |
|
MARCKS |
1994 |
Protein kinase C-mediated phosphorylation and calmodulin binding of
recombinant myristoylated alanine-rich C kinase substrate (MARCKS) and
MARCKS-related protein |
http://www.ncbi.nlm.nih.gov/pubmed/8132675 |
|
MARCKS |
1994 |
Specificity of the high affinity interaction of protein kinase C with a
physiological substrate, myristoylated alanine-rich protein kinase C
substrate |
http://www.ncbi.nlm.nih.gov/pubmed/7989336 |
|
MARCKS |
1995 |
The myristoylated alanine-rich C-kinase substrate (MARCKS) is not
required for mitogenic signalling via protein kinase C in cultured rat
intestinal epithelial (RIE-1) cells |
http://www.ncbi.nlm.nih.gov/pubmed/7549920 |
|
MARCKS |
1995 |
The myristoylated alanine-rich C-kinase substrate (MARCKS) is
sequentially phosphorylated by conventional, novel and atypical isotypes
of protein kinase C |
http://www.ncbi.nlm.nih.gov/pubmed/7588787 |
|
MARCKS |
1996 |
PRK1 phosphorylates MARCKS at the PKC sites: serine 152, serine 156 and
serine 163 |
http://www.ncbi.nlm.nih.gov/pubmed/8557118 |
|
MARCKS |
1996 |
Thrombin-induced phosphorylation of the myristoylated alanine-rich C
kinase substrate (MARCKS) protein in bovine pulmonary artery endothelial
cells |
http://www.ncbi.nlm.nih.gov/pubmed/8908202 |
|
MARCKS |
1997 |
Activation of protein kinase C-alpha and translocation of the
myristoylated alanine-rich C-kinase substrate correlate with phorbol
ester-enhanced noradrenaline release from SH-SY5Y human neuroblastoma
cells |
http://www.ncbi.nlm.nih.gov/pubmed/8978751 |
|
MARCKS |
1997 |
Expression and regulation of 80K/MARCKS, a major substrate of protein
kinase C, in the developing rat heart |
http://www.ncbi.nlm.nih.gov/pubmed/9205551 |
|
MARCKS |
1997 |
The major myristoylated PKC substrate (MARCKS) is involved in cell
spreading, tyrosine phosphorylation of paxillin, and focal contact
formation |
http://www.ncbi.nlm.nih.gov/pubmed/9426227 |
|
MARCKS |
1998 |
Overexpression of myristoylated alanine-rich C-kinase substrate enhances
activation of phospholipase D by protein kinase C in SK-N-MC human
neuroblastoma cells |
http://www.ncbi.nlm.nih.gov/pubmed/9601059 |
|
MARCKS |
1999 |
Expression of the myristoylated alanine-rich C kinase substrate (MARCKS)
and MARCKS-related protein (MRP) in the prefrontal cortex and
hippocampus of suicide victims |
http://www.ncbi.nlm.nih.gov/pubmed/10073384 |
|
MARCKS |
1999 |
Myristoylated alanine-rich C-kinase substrate is phosphorylated and
translocated by a phorbol ester-insensitive and calcium-independent
protein kinase C isoform in C6 glioma cell membranes |
http://www.ncbi.nlm.nih.gov/pubmed/9990296 |
|
MARCKS |
1999 |
Phosphorylation of the myristoylated protein kinase C substrate MARCKS
by the cyclin E-cyclin-dependent kinase 2 complex in vitro |
http://www.ncbi.nlm.nih.gov/pubmed/10359664 |
|
MARCKS |
2000 |
Importance of protein kinase C targeting for the phosphorylation of its
substrate, myristoylated alanine-rich C-kinase substrate |
http://www.ncbi.nlm.nih.gov/pubmed/10840037 |
|
MARCKS |
2000 |
Involvement of protein kinase C epsilon in thyrotropin-releasing
hormone-stimulated phosphorylation of the myristoylated alanine-rich C
kinase substrate in rat pituitary clonal cells |
http://www.ncbi.nlm.nih.gov/pubmed/10675027 |
|
MARCKS |
2000 |
Involvement of the theta-type protein kinase C in translocation of
myristoylated alanine-rich C kinase substrate (MARCKS) during myogenesis
of chick embryonic myoblasts |
http://www.ncbi.nlm.nih.gov/pubmed/10727412 |
|
MARCKS |
2001 |
Microglial signaling by amyloid beta protein through mitogen-activated
protein kinase mediating phosphorylation of MARCKS. |
http://www.ncbi.nlm.nih.gov/pubmed/11496150 |
|
MARCKS |
2001 |
Prostaglandin F2alpha-activated protein kinase Calpha phosphorylates
myristoylated alanine-rich C kinase substrate protein in bovine luteal
cells |
http://www.ncbi.nlm.nih.gov/pubmed/11887938 |
|
MARCKS |
2003 |
Neuroanatomical development in the absence of PKC phosphorylation of the
myristoylated alanine-rich C-kinase substrate (MARCKS) protein |
http://www.ncbi.nlm.nih.gov/pubmed/12888215 |
|
MARCKS |
2003 |
The 3'-UTR of the mRNA coding for the major protein kinase C substrate
MARCKS contains a novel CU-rich element interacting with the mRNA
stabilizing factors HuD and HuR |
http://www.ncbi.nlm.nih.gov/pubmed/12605686 |
|
MARCKS |
2004 |
Myristoylated alanine-rich C kinase substrate (MARCKS) is involved in
myoblast fusion through its regulation by protein kinase Calpha and
calpain proteolytic cleavage |
http://www.ncbi.nlm.nih.gov/pubmed/15239673 |
|
MARCKS |
2005 |
Myristoylated alanine-rich C kinase substrate-mediated neurotensin
release via protein kinase C-delta downstream of the Rho/ROK pathway |
http://www.ncbi.nlm.nih.gov/pubmed/15623535 |
|
MARCKS |
1996 |
Binding of myristoylated alanine-rich protein kinase C substrate to
phosphoinositides attenuates the phosphorylation by protein kinase C |
http://www.ncbi.nlm.nih.gov/pubmed/8611023 |
|
MARCKS, B-50, dephosphin |
1991 |
The role of protein kinase C and its neuronal substrates dephosphin,
B-50, and MARCKS in neurotransmitter release |
http://www.ncbi.nlm.nih.gov/pubmed/1688057 |
|
MARCKS, MLP, GAP-43, RC3 |
2000 |
Differential regulation of primary protein kinase C substrate (MARCKS,
MLP, GAP-43, RC3) mRNAs in the hippocampus during kainic acid-induced
seizures and synaptic reorganization |
http://www.ncbi.nlm.nih.gov/pubmed/11054811 |
|
MARCKS, MRP |
1997 |
Calcium binding and conformational properties of calmodulin complexed
with peptides derived from myristoylated alanine-rich C kinase substrate
(MARCKS) and MARCKS-related protein (MRP) |
http://www.ncbi.nlm.nih.gov/pubmed/9112755 |
|
MARCKS, neuromodulin, and neurogranin |
1995 |
Differential responses of protein kinase C substrates (MARCKS,
neuromodulin, and neurogranin) phosphorylation to calmodulin and S100 |
http://www.ncbi.nlm.nih.gov/pubmed/7840634 |
|
MARCKS, neuromodulin, neurogranin |
1998 |
Phosphorylation of protein kinase C substrate proteins in rat
hippocampal slices--effect of calpain inhibition |
http://www.ncbi.nlm.nih.gov/pubmed/9949550 |
|
MARCKS-PSD |
2000 |
Characterization of a selective protein kinase C substrate derived from
the MARCKS phosphorylation site domain for use in brain tissue
homogenates |
http://www.ncbi.nlm.nih.gov/pubmed/10660461 |
|
MEK/ERK |
1996 |
Protein kinase C activates the MEK-ERK pathway in a manner independent
of Ras and dependent on Raf |
http://www.ncbi.nlm.nih.gov/pubmed/8798560 |
|
Mlgl |
2003 |
A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and
regulates mammalian Lgl |
http://www.ncbi.nlm.nih.gov/pubmed/12629547 |
|
MPF [p34(cdc2) and cyclin B] |
2004 |
Effects of protein kinase C on M-phase promoting factor in early
development of fertilized mouse eggs |
http://www.ncbi.nlm.nih.gov/pubmed/15338468 |
|
myosin II-B |
2008 |
Protein kinase C-dependent {alpha}-secretory processing of the amyloid
precursor protein is mediated by phosphorylation of myosin II-B |
http://www.ncbi.nlm.nih.gov/pubmed/19103644 |
|
Na,K-ATPase (alpha 1 subunit) |
1996 |
alpha 1 but not alpha 2 or alpha 3 isoforms of Na,K-ATPase are
efficiently phosphorylated in a novel protein kinase C motif |
http://www.ncbi.nlm.nih.gov/pubmed/8916895 |
|
Na,K-ATPase (alpha 1 subunit) |
2000 |
Is phosphorylation of the alpha1 subunit at Ser-16 involved in the
control of Na,K-ATPase activity by phorbol ester-activated protein
kinase C? |
http://www.ncbi.nlm.nih.gov/pubmed/10637289 |
|
NADPH oxidase |
1993 |
Inhibition of neutrophil NADPH oxidase assembly by a myristoylated
pseudosubstrate of protein kinase C |
http://www.ncbi.nlm.nih.gov/pubmed/8360154 |
|
Nef |
1995 |
The human immunodeficiency virus type 1 Nef protein functions as a
protein kinase C substrate in vitro |
http://www.ncbi.nlm.nih.gov/pubmed/9049329 |
|
Neurogranin |
1990 |
Neurogranin: immunocytochemical localization of a brain-specific protein
kinase C substrate |
http://www.ncbi.nlm.nih.gov/pubmed/2269883 |
|
Neurogranin |
1991 |
A rapid purification method for neurogranin, a brain specific
calmodulin-binding protein kinase C substrate |
http://www.ncbi.nlm.nih.gov/pubmed/2026258 |
|
Neurogranin |
1993 |
Characterization of a 7.5-kDa protein kinase C substrate (RC3 protein,
neurogranin) from rat brain |
http://www.ncbi.nlm.nih.gov/pubmed/8080473 |
|
Neurogranin |
1993 |
Functional consequences of expression of the neuron-specific, protein
kinase C substrate RC3 (neurogranin) in Xenopus oocytes |
http://www.ncbi.nlm.nih.gov/pubmed/8293295 |
|
Neurogranin |
1993 |
Mechanism of protein kinase C activation during the induction and
maintenance of long-term potentiation probed using a selective peptide
substrate |
http://www.ncbi.nlm.nih.gov/pubmed/8378303 |
|
Neurogranin |
1993 |
Studies with synthetic peptide substrates derived from the neuronal
protein neurogranin reveal structural determinants of potency and
selectivity for protein kinase C |
http://www.ncbi.nlm.nih.gov/pubmed/8424932 |
|
Neurogranin |
1995 |
Antibodies to postsynaptic PKC substrate neurogranin prevent long-term
potentiation in hippocampal CA1 neurons |
http://www.ncbi.nlm.nih.gov/pubmed/7620629 |
|
Neurogranin |
1995 |
Structure and regulation of the gene encoding the neuron-specific
protein kinase C substrate neurogranin (RC3 protein) |
http://www.ncbi.nlm.nih.gov/pubmed/7730337 |
|
Neurogranin |
1997 |
Enhanced phosphorylation of the postsynaptic protein kinase C substrate
RC3/neurogranin during long-term potentiation |
http://www.ncbi.nlm.nih.gov/pubmed/9138717 |
|
Neurogranin |
2003 |
Structural and dynamic characterization of a neuron-specific protein
kinase C substrate, neurogranin |
http://www.ncbi.nlm.nih.gov/pubmed/12718558 |
|
Neurogranin |
2009 |
Electroconvulsive seizure increases phosphorylation of PKC substrates,
including GAP-43, MARCKS, and neurogranin, in rat brain. |
http://www.ncbi.nlm.nih.gov/pubmed/19837121 |
|
Neurogranin, neuromodulin |
1993 |
Use of the synthetic peptide neurogranin(28-43) as a selective protein
kinase C substrate in assays of tissue homogenates |
http://www.ncbi.nlm.nih.gov/pubmed/8122777 |
|
Neurogranin, neuromodulin, MARCKS |
1995 |
Dephosphorylation of protein kinase C substrates, neurogranin,
neuromodulin, and MARCKS, by calcineurin and protein phosphatases 1 and
2A |
http://www.ncbi.nlm.nih.gov/pubmed/7864622 |
|
Neuromodulin |
1990 |
Neuron-specific protein F1/GAP-43 shows substrate specificity for the
beta subtype of protein kinase C |
http://www.ncbi.nlm.nih.gov/pubmed/2145833 |
|
Neuromodulin |
1991 |
Microencephaly reduces the phosphorylation of the PKC substrate
B-50/GAP43 in rat cortex and hippocampus |
http://www.ncbi.nlm.nih.gov/pubmed/1826859 |
|
Neuromodulin |
1991 |
The interactions of the brain-specific calmodulin-binding protein kinase
C substrate, neuromodulin (GAP 43), with membrane phospholipids |
http://www.ncbi.nlm.nih.gov/pubmed/1826685 |
|
Neuromodulin |
1993 |
Evidence for a role of protein kinase C substrate B-50 (GAP-43) in
Ca(2+)-induced neuropeptide cholecystokinin-8 release from permeated
synaptosomes |
http://www.ncbi.nlm.nih.gov/pubmed/8336144 |
|
Neuromodulin |
1994 |
Presynaptic PKC substrate B-50 (GAP-43) and neurotransmitter release:
studies with permeated synaptosomes |
http://www.ncbi.nlm.nih.gov/pubmed/7916446 |
|
Neuromodulin |
1995 |
Changes in protein kinase C and its presynaptic substrate B-50/GAP-43
after intrauterine exposure to methylazoxy-methanol, a treatment
inducing cortical and hippocampal damage and cognitive deficit in rats |
http://www.ncbi.nlm.nih.gov/pubmed/7613626 |
|
Neuromodulin |
1999 |
1,2-dioctanoyl-s,n-glycerol-induced activation of protein kinase C
results in striking, but reversible growth cone shape changes and an
accumulation of f-actin and serine 41-phosphorylated GAP-43 in the
axonal process |
http://www.ncbi.nlm.nih.gov/pubmed/10569242 |
|
Neuromodulin |
1999 |
The protein kinase C (PKC) substrate GAP-43 is already expressed in
neural precursor cells, colocalizes with PKCeta and binds calmodulin |
http://www.ncbi.nlm.nih.gov/pubmed/10051751 |
|
NFAT |
2002 |
Protein kinase Czeta phosphorylates nuclear factor of activated T cells
and regulates its transactivating activity |
http://www.ncbi.nlm.nih.gov/pubmed/12021260 |
|
NG(28-43) |
1997 |
Conformation of a protein kinase C substrate NG(28-43), and its analog
in aqueous and sodium dodecyl sulfate micelle solutions |
http://www.ncbi.nlm.nih.gov/pubmed/9017186 |
|
NMDA receptor |
1994 |
Protein kinase C transiently activated heteromeric N-methyl-D-aspartate
receptor channels independent of the phosphorylatable C-terminal splice
domain and of consensus phosphorylation sites |
http://www.ncbi.nlm.nih.gov/pubmed/7510681 |
|
NMDA receptor |
1997 |
Cyclic AMP-dependent protein kinase and protein kinase C phosphorylate
N-methyl-D-aspartate receptors at different sites |
http://www.ncbi.nlm.nih.gov/pubmed/9115280 |
|
Nonmuscle myosin-II heavy chain |
2001 |
Protein kinase C phosphorylates nonmuscle myosin-II heavy chain from
Drosophila but regulation of myosin function by this enzyme is not
required for viability in flies. |
http://www.ncbi.nlm.nih.gov/pubmed/11297427 |
|
Nucleolin |
1997 |
Nucleolin is a protein kinase C-zeta substrate. Connection between cell
surface signaling and nucleus in PC12 cells |
http://www.ncbi.nlm.nih.gov/pubmed/9388266 |
|
occludin |
2009 |
PKC eta regulates occludin phosphorylation and epithelial tight junction
integrity |
http://www.ncbi.nlm.nih.gov/pubmed/19114660 |
|
P2 protamines |
1994 |
P2 protamines are phosphorylated in vitro by protein kinase C, whereas
P1 protamines prefer cAMP-dependent protein kinase. A comparative study
of five mammalian species |
http://www.ncbi.nlm.nih.gov/pubmed/8033890 |
|
p21ras proteins |
1993 |
p21ras function is important for T cell antigen receptor and protein
kinase C regulation of nuclear factor of activated T cells |
http://www.ncbi.nlm.nih.gov/pubmed/8473736 |
|
p21WAF-1 |
1997 |
Up-regulation of p21WAF1 expression in myeloid cells is activated by the
protein kinase C pathway |
http://www.ncbi.nlm.nih.gov/pubmed/9413940 |
|
p22(phox), NADPH oxidase |
1999 |
A phosphatidic acid-activated protein kinase and conventional protein
kinase C isoforms phosphorylate p22(phox), an NADPH oxidase component |
http://www.ncbi.nlm.nih.gov/pubmed/10593961 |
|
p42 MAPK |
1992 |
Selective activation of p42 mitogen-activated protein (MAP) kinase in
murine B lymphoma cell lines by membrane immunoglobulin cross-linking.
Evidence for protein kinase C-independent and -dependent mechanisms of
activation |
http://www.ncbi.nlm.nih.gov/pubmed/1384467 |
|
p47(phox) |
2004 |
Superoxide production at phagosomal cup/phagosome through beta I protein
kinase C during Fc gamma R-mediated phagocytosis in microglia |
http://www.ncbi.nlm.nih.gov/pubmed/15383592 |
|
p47phox |
2004 |
Protein kinase C delta is required for p47phox phosphorylation and
translocation in activated human monocytes |
http://www.ncbi.nlm.nih.gov/pubmed/15494525 |
|
p47phox |
2001 |
Protein kinase C zeta phosphorylates a subset of selective sites of the
NADPH oxidase component p47phox and participates in formyl
peptide-mediated neutrophil respiratory burst. |
http://www.ncbi.nlm.nih.gov/pubmed/11145703 |
|
p50 LSP1 |
1995 |
Protein kinase C phosphorylates p50 LSP1 and induces translocation of
p50 LSP1 in T lymphocytes |
http://www.ncbi.nlm.nih.gov/pubmed/7775393 |
|
p53 |
1996 |
Murine p53 is phosphorylated within the PAb421 epitope by protein kinase
C in vitro, but not in vivo, even after stimulation with the phorbol
ester o-tetradecanoylphorbol 13-acetate |
http://www.ncbi.nlm.nih.gov/pubmed/8700548 |
|
p57 MAP kinase |
1996 |
Protein kinase C beta 1 and protein kinase C beta 2 activate p57
mitogen-activated protein kinase and block differentiation in colon
carcinoma cells |
http://www.ncbi.nlm.nih.gov/pubmed/8732668 |
|
p60TNFR |
2000 |
Serine phosphorylation of p60 tumor necrosis factor receptor by
PKC-delta in TNF-alpha-activated neutrophils |
http://www.ncbi.nlm.nih.gov/pubmed/11078718 |
|
PAR-1 |
2004 |
Atypical PKC phosphorylates PAR-1 kinases to regulate localization and
activity |
http://www.ncbi.nlm.nih.gov/pubmed/15084291 |
|
PB1-F2 |
2009 |
Phosphorylation of the influenza A virus protein PB1-F2 by PKC is
crucial for apoptosis promoting functions in monocytes. |
http://www.ncbi.nlm.nih.gov/pubmed/19523156 |
|
PEA-15 |
1993 |
Characterization of PEA-15, a major substrate for protein kinase C in
astrocytes |
http://www.ncbi.nlm.nih.gov/pubmed/8449955 |
|
P-glycoprotein |
1990 |
Protein kinase C phosphorylates P-glycoprotein in multidrug resistant
human KB carcinoma cells |
http://www.ncbi.nlm.nih.gov/pubmed/1970571 |
|
P-glycoprotein |
1996 |
Partial reversal of multidrug resistance in human breast cancer cells by
an N-myristoylated protein kinase C-alpha pseudosubstrate peptide |
http://www.ncbi.nlm.nih.gov/pubmed/8567666 |
|
P-glycoprotein |
1997 |
An N-myristoylated protein kinase C-alpha pseudosubstrate peptide that
functions as a multidrug resistance reversal agent in human breast
cancer cells is not a P-glycoprotein substrate |
http://www.ncbi.nlm.nih.gov/pubmed/9272125 |
|
P-glycoprotein |
1994 |
Regulation of volume activated chloride channels by protein kinase
C-mediated phosphorylation of P-glycoprotein |
http://www.ncbi.nlm.nih.gov/pubmed/7752561 |
|
P-glycoprotein |
1995 |
Protein kinase C-mediated phosphorylation of the human multidrug
resistance P-glycoprotein regulates cell volume-activated chloride
channels |
http://www.ncbi.nlm.nih.gov/pubmed/7828597 |
|
Phospholipase D |
1992 |
Calcium rather than protein kinase C is the major factor to activate
phospholipase D in FMLP-stimulated rabbit peritoneal neutrophils.
Possible involvement of calmodulin/myosin L chain kinase pathway |
http://www.ncbi.nlm.nih.gov/pubmed/1624805 |
|
Phospholipase D |
1995 |
Genistein inhibits potentiation by wortmannin of protein kinase
C-activated phospholipase D in osteoblast-like cells |
http://www.ncbi.nlm.nih.gov/pubmed/7662510 |
|
Phospholipase D |
1995 |
Regulation of phospholipase D by protein kinase C in human neutrophils.
Conventional isoforms of protein kinase C phosphorylate a phospholipase
D-related component in the plasma membrane |
http://www.ncbi.nlm.nih.gov/pubmed/7642630 |
|
Phospholipase D |
2004 |
Isoenzyme-specific translocation of protein kinase C (PKC)betaII and not
PKCbetaI to a juxtanuclear subset of recycling endosomes: involvement of
phospholipase D |
http://www.ncbi.nlm.nih.gov/pubmed/15067001 |
|
Phospholipase D1 |
1999 |
Phospholipase D1 is located and activated by protein kinase C alpha in
the plasma membrane in 3Y1 fibroblast cell |
http://www.ncbi.nlm.nih.gov/pubmed/9989263 |
|
Phospholipase D1 |
2000 |
Phospholipase D1 is phosphorylated and activated by protein kinase C in
caveolin-enriched microdomains within the plasma membrane |
http://www.ncbi.nlm.nih.gov/pubmed/10788479 |
|
Phospholipase D1 |
2002 |
Phospholipase D1 is threonine-phosphorylated in human-airway epithelial
cells stimulated by sphingosine-1-phosphate by a mechanism involving Src
tyrosine kinase and protein kinase Cdelta |
http://www.ncbi.nlm.nih.gov/pubmed/12014986 |
|
Phospholipase D1 |
2004 |
Protein kinase Calpha translocates to the perinuclear region to activate
phospholipase D1 |
http://www.ncbi.nlm.nih.gov/pubmed/15187091 |
|
PICK1 |
1995 |
PICK1: a perinuclear binding protein and substrate for protein kinase C
isolated by the yeast two-hybrid system |
http://www.ncbi.nlm.nih.gov/pubmed/7844141 |
|
PKD |
2003 |
Protein kinase C phosphorylates protein kinase D activation loop Ser744
and Ser748 and releases autoinhibition by the pleckstrin homology domain |
http://www.ncbi.nlm.nih.gov/pubmed/12407104 |
|
PKD1 |
2005 |
Dual phospholipase C/diacylglycerol requirement for protein kinase D1
activation in lymphocytes |
http://www.ncbi.nlm.nih.gov/pubmed/15590638 |
|
Pleckstrin |
1989 |
Molecular analysis of pleckstrin: the major protein kinase C substrate
of platelets |
http://www.ncbi.nlm.nih.gov/pubmed/2768345 |
|
Pleckstrin |
1999 |
Expression of the protein kinase C substrate pleckstrin in macrophages:
association with phagosomal membranes |
http://www.ncbi.nlm.nih.gov/pubmed/10477609 |
|
Pleckstrin |
2004 |
Association of CBFA2 mutation with decreased platelet PKC-theta and
impaired receptor-mediated activation of GPIIb-IIIa and pleckstrin
phosphorylation: proteins regulated by CBFA2 play a role in GPIIb-IIIa
activation |
http://www.ncbi.nlm.nih.gov/pubmed/14525764 |
|
PPARalpha |
2001 |
The transcription of the peroxisome proliferator-activated receptor
alpha gene is regulated by protein kinase C |
http://www.ncbi.nlm.nih.gov/pubmed/11701232 |
|
PPARalpha |
2004 |
The protein kinase C signaling pathway regulates a molecular switch
between transactivation and transrepression activity of the peroxisome
proliferator-activated receptor alpha |
http://www.ncbi.nlm.nih.gov/pubmed/15131257 |
|
PRKX |
2002 |
PRKX, a phylogenetically and functionally distinct cAMP-dependent
protein kinase, activates renal epithelial cell migration and
morphogenesis |
http://www.ncbi.nlm.nih.gov/pubmed/12082174 |
|
Proinsulin C-peptide |
2001 |
Proinsulin C-peptide rapidly stimulates mitogen-activated protein
kinases in Swiss 3T3 fibroblasts: requirement of protein kinase C,
phosphoinositide 3-kinase and pertussis toxin-sensitive G-protein. |
http://www.ncbi.nlm.nih.gov/pubmed/11256956 |
|
PU.1 |
2004 |
IFN-gamma induces gp91phox expression in human monocytes via protein
kinase C-dependent phosphorylation of PU.1 |
http://www.ncbi.nlm.nih.gov/pubmed/15067074 |
|
pVHL |
2001 |
The von Hippel-Lindau tumor suppressor protein mediates ubiquitination
of activated atypical protein kinase C |
http://www.ncbi.nlm.nih.gov/pubmed/11574546 |
|
Pyk2 |
1998 |
Differential stimulation of proline-rich tyrosine kinase 2 and
mitogen-activated protein kinase by sphingosine 1-phosphate |
http://www.ncbi.nlm.nih.gov/pubmed/9826186 |
|
Rab6C |
1999 |
Rab6 is phosphorylated in thrombin-activated platelets by a protein
kinase C-dependent mechanism: effects on GTP/GDP binding and cellular
distribution |
http://www.ncbi.nlm.nih.gov/pubmed/10455022 |
|
RACK1 |
2000 |
The influenza A virus M1 protein interacts with the cellular receptor of
activated C kinase (RACK) 1 and can be phosphorylated by protein kinase
C |
http://www.ncbi.nlm.nih.gov/pubmed/10799781 |
|
RACK1 |
2001 |
Increased association of brain protein kinase C with the receptor for
activated C kinase-1 (RACK1) in bipolar affective disorder. |
http://www.ncbi.nlm.nih.gov/pubmed/11543740 |
|
RACKs |
2002 |
RACK1: a novel substrate for the Src protein-tyrosine kinase |
http://www.ncbi.nlm.nih.gov/pubmed/12400005 |
|
Raf-1 |
1993 |
Protein kinase C alpha activates RAF-1 by direct phosphorylation |
http://www.ncbi.nlm.nih.gov/pubmed/8321321 |
|
Raf-1 |
1994 |
Protein kinase C-mediated serine phosphorylation directly activates
Raf-1 in murine hematopoietic cells |
|
