|
PKC Inhibitor |
Year |
Title |
Web link |
|
13-HODE |
1999 |
The lipoxygenase product 13-hydroxyoctadecadienoic acid (13-HODE) is a
selective inhibitor of classical PKC isoenzymes |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10079174 |
|
Annexin V |
1995 |
Inhibitory effect of annexin V on protein kinase C activity in mesangial
cell lysates |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7588728 |
|
Aprinocarsen |
2004 |
The role of protein kinase C-alpha in malignancies of the nervous system
and implications for the clinical development of the specific PKC-alpha
inhibitor aprinocarsen (Review) |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14719093 |
|
Bisindolylmaleimide GF 109203X |
1991 |
The bisindolylmaleimide GF 109203X is a potent and selective inhibitor
of protein kinase C |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1874734 |
|
Bryostatin-1 |
2003 |
Bryostatin-1: a novel PKC inhibitor in clinical development |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14735696 |
|
BSP-A1/-A2 |
2003 |
The inhibitory effect of BSP-A1/-A2 on protein kinase C and tyrosine
protein kinase |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12736909 |
|
Butein |
1998 |
Butein, a specific protein tyrosine kinase inhibitor |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9571170 |
|
Calphostin C |
1992 |
Irreversible oxidative inactivation of protein kinase C by
photosensitive inhibitor calphostin C |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1281116 |
|
Calphostin C |
1997 |
Isoform specificity of activators and inhibitors of protein kinase C
gamma and delta |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9326378 |
|
Chelerythrine |
1990 |
Chelerythrine is a potent and specific inhibitor of protein kinase C |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2244923 |
|
Chelerythrine chloride |
2001 |
Investigation of the inhibitory effects of chelerythrine chloride on the
translocation of the protein kinase C betaI, betaII, zeta in human
neutrophils |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11765038 |
|
Curcumin |
1993 |
Inhibitory effects of curcumin on protein kinase C activity induced by
12-O-tetradecanoyl-phorbol-13-acetate in NIH 3T3 cells |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8504477 |
|
Daphnetin |
1999 |
Daphnetin, one of coumarin derivatives, is a protein kinase inhibitor |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10403826 |
|
Erbstatin |
1990 |
Inhibition of protein kinase C by the tyrosine kinase inhibitor
erbstatin |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2242040 |
|
H-7 |
1992 |
The structure and biological activities of the widely used protein
kinase inhibitor, H7, differ depending on the commercial source |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1530623 |
|
Hispidin |
1997 |
Synthetic hispidin, a PKC inhibitor, is more cytotoxic toward cancer
cells than normal cells in vitro |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9088624 |
|
Hypocrellin A |
2003 |
Inhibitory effect of hypocrellin A on protein kinase C in liver and
skeletal muscle of obese Zucker rats |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14992539 |
|
LY333531 |
2003 |
Selective protein kinase C inhibitors and their applications |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14683472 |
|
Midostaurin |
2001 |
Protein kinase C inhibitors as novel anticancer drugs |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11772309 |
|
N-myristyl-Lys-Arg-Thr-Leu-Arg |
1990 |
N-myristyl-Lys-Arg-Thr-Leu-Arg: a novel protein kinase C inhibitor |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2153382 |
|
NPC 15437 |
1991 |
2,6-Diamino-N-([1-oxotridecyl)-2-piperidinyl]methyl)hexanamide (NPC
15437): a selective inhibitor of protein kinase C |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1793019 |
|
PAP |
1996 |
Phenylamino-pyrimidine (PAP) derivatives: a new class of potent and
selective inhibitors of protein kinase C (PKC) |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8764886 |
|
PKC412 |
2000 |
PKC412--a protein kinase inhibitor with a broad therapeutic potential |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8764886 |
|
PKC412 |
2008 |
Inhibition of PKCalpha activation in human bone and soft tissue sarcoma
cells by the selective PKC inhibitor PKC412 |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18507025; |
|
R8605 |
1991 |
[The inhibitory effect of a third generation retinoid, R8605, on protein
kinase C activity in vitro] |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1839520 |
|
RK-286C |
1990 |
A new inhibitor of protein kinase C, RK-286C (4'-demethylamino-4'-hydroxystaurosporine).
I. Screening, taxonomy, fermentation and biological activity |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2312404 |
|
Ro 31-8220 |
1996 |
Atypical isoforms of pKc and insulin secretion from pancreatic
beta-cells: evidence using Go 6976 and Ro 31-8220 as Pkc inhibitors |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8885992 |
|
Rottlerin |
1994 |
Rottlerin, a novel protein kinase inhibitor |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8123051 |
|
Rottlerin |
2003 |
Isoform-selectivity of PKC inhibitors acting at the regulatory and
catalytic domain of mammalian PKC-alpha, -betaI, -delta, -eta and -zeta |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15008511 |
|
Staurosporine |
1989 |
The protein kinase inhibitor staurosporine, like phorbol esters, induces
the association of protein kinase C with membranes |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3408497 |
|
Staurosporine |
1992 |
Protein kinase C-dependent and -independent actions of a potent protein
kinase C inhibitor, staurosporine |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1426027 |
|
UCN-01 |
1995 |
UCN-01, an anti-tumor drug, is a selective inhibitor of the conventional
PKC subfamily |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7867810 |
|
UCN-01 and UCN-02 |
1989 |
UCN-01 and UCN-02, new selective inhibitors of protein kinase C. I.
Screening, producing organism and fermentation |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2722672 |
|
UCN-01 and UCN-02 |
1989 |
UCN-01 and UCN-02, new selective inhibitors of protein kinase C. II.
Purification, physico-chemical properties, structural determination and
biological activities |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2656615 |
|
Vanicosides A and B |
1994 |
Vanicosides A and B, protein kinase C inhibitors from Polygonum
pensylvanicum |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8176400 |
|
Verbascoside |
1991 |
Verbascoside isolated from Lantana camara, an inhibitor of protein
kinase C |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1812212 |
